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Functional Significance of Genetic Polymorphisms in P-glycoprotein (MDR1, ABCB1) and Breast Cancer Resistance Protein (BCRP, ABCG2)

DRUG METABOLISM AND PHARMACOKINETICS, 2012, Vol.27 (1), p.85-105

Ieiri, Ichiro

2012

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An updated review of pharmacokinetic drug interactions and pharmacogenetics of statins

Expert opinion on drug metabolism & toxicology, 2020-09, Vol.16 (9), p.809-822

2020

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Impact of Genetic Polymorphisms in CYP2C9 and CYP2C19 on the Pharmacokinetics of Clinically Used Drugs

DRUG METABOLISM AND PHARMACOKINETICS, 2013, Vol.28 (1), p.28-37

2013

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Clinical Pharmacokinetics and Pharmacodynamics of Fostamatinib and Its Active Moiety R406

Clinical pharmacokinetics, 2022-07, Vol.61 (7), p.955-972

2022

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Clinical Pharmacokinetics of Anaplastic Lymphoma Kinase Inhibitors in Non-Small-Cell Lung Cancer

Clinical pharmacokinetics, 2019-04, Vol.58 (4), p.403-420

2019

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Identification of drug transporters contributing to oxaliplatin‐induced peripheral neuropathy

Journal of neurochemistry, 2019-02, Vol.148 (3), p.373-385

2019

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Prognostic significance of pre-treatment ALBI grade in advanced non-small cell lung cancer receiving immune checkpoint therapy

Scientific reports, 2021-07, Vol.11 (1), p.15057-15057, Article 15057

2021

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Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs

Expert opinion on drug metabolism & toxicology, 2009-07, Vol.5 (7), p.703-729

2009

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Development and Full Validation of a Bioanalytical Method for Quantifying Letermovir in Human Plasma Using Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry

Chemical and Pharmaceutical Bulletin, 2021/07/01, Vol.69(7), pp.646-651

2021

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Nucleosome Positioning and Gene Regulation of the SGLT2 Gene in the Renal Proximal Tubular Epithelial Cells

Molecular pharmacology, 2018-09, Vol.94 (3), p.953-962

2018

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Detection of overdose and underdose prescriptions-An unsupervised machine learning approach

PloS one, 2021-11, Vol.16 (11), p.e0260315-e0260315

2021

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Optimal Teicoplanin Dosing Regimen in Neonates and Children Developed by Leveraging Real-World Clinical Information

Therapeutic drug monitoring, 2022-06, Vol.44 (3), p.404

2022

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Development and Validation of A Liquid Chromatography-Tandem Mass Spectrometry Method to Simultaneously Measure Tacrolimus and Everolimus Concentrations in Kidney Allograft Biopsies After Kidney Transplantation

Therapeutic drug monitoring, 2022-04, Vol.44 (2), p.275

2022

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The mTOR inhibitor everolimus attenuates tacrolimus-induced renal interstitial fibrosis in rats

Life sciences (1973), 2022-01, Vol.288, p.120150, Article 120150

2022

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Risk Factors of Cetuximab-Induced Hypomagnesemia and the Effect of Magnesium Prophylaxis in Patients with Head and Neck Cancer: A Retrospective Study

Biological and Pharmaceutical Bulletin, 2024/03/29, Vol.47(3), pp.732-738

2024

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Neuroprotective effects of ibudilast against tacrolimus induced neurotoxicity

Toxicology and applied pharmacology, 2022-08, Vol.449, p.116112-116112, Article 116112

2022

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Reduced theophylline clearance due to hepatic congestion secondary to right heart failure - A population pharmacokinetic study

Drug metabolism and pharmacokinetics, 2021-12, Vol.41, p.100403-100403, Article 100403

2021

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Human organic cation transporter ( and ) gene polymorphisms and therapeutic effects of metformin

Journal of human genetics, 2007-02, Vol.52 (2), p.117-122

2007

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Establishment of an experimental rat model of tacrolimus-induced kidney injury accompanied by interstitial fibrosis

Toxicology letters, 2021-05, Vol.341, p.43-50

2021

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Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP

British journal of pharmacology, 2012-07, Vol.166 (6), p.1793-1803

2012

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Involvement of Organic Cation Transporters in the Kinetics of Trimethylamine N-oxide

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2542-2550

2017

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What Are Barriers to Pharmacogenomics (PGx) Clinical Uptake?

Drug metabolism and pharmacokinetics, 2012, Vol.27 (3), p.279-279

Ieiri, Ichiro

2012

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Population Pharmacokinetic and Pharmacodynamic Analysis of Linezolid and a Hematologic Side Effect, Thrombocytopenia, in Japanese Patients

Antimicrobial Agents and Chemotherapy, 2011-05, Vol.55 (5), p.1867-1873

2011

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Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers

Drug metabolism and pharmacokinetics, 2019-02, Vol.34 (1), p.78-86

2019

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Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2688-2694

2017

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Functional Significance of Genetic Polymorphisms in P-glycoprotein (MDR1, ABCB1) and Breast Cancer Resistance Protein (BCRP, ABCG2)

An updated review of pharmacokinetic drug interactions and pharmacogenetics of statins

Impact of Genetic Polymorphisms in CYP2C9 and CYP2C19 on the Pharmacokinetics of Clinically Used Drugs

Clinical Pharmacokinetics and Pharmacodynamics of Fostamatinib and Its Active Moiety R406

Clinical Pharmacokinetics of Anaplastic Lymphoma Kinase Inhibitors in Non-Small-Cell Lung Cancer

Identification of drug transporters contributing to oxaliplatin‐induced peripheral neuropathy

Prognostic significance of pre-treatment ALBI grade in advanced non-small cell lung cancer receiving immune checkpoint therapy

Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs

Development and Full Validation of a Bioanalytical Method for Quantifying Letermovir in Human Plasma Using Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry

Nucleosome Positioning and Gene Regulation of the SGLT2 Gene in the Renal Proximal Tubular Epithelial Cells

Detection of overdose and underdose prescriptions-An unsupervised machine learning approach

Optimal Teicoplanin Dosing Regimen in Neonates and Children Developed by Leveraging Real-World Clinical Information

Development and Validation of A Liquid Chromatography-Tandem Mass Spectrometry Method to Simultaneously Measure Tacrolimus and Everolimus Concentrations in Kidney Allograft Biopsies After Kidney Transplantation

The mTOR inhibitor everolimus attenuates tacrolimus-induced renal interstitial fibrosis in rats

Risk Factors of Cetuximab-Induced Hypomagnesemia and the Effect of Magnesium Prophylaxis in Patients with Head and Neck Cancer: A Retrospective Study

Neuroprotective effects of ibudilast against tacrolimus induced neurotoxicity

Reduced theophylline clearance due to hepatic congestion secondary to right heart failure - A population pharmacokinetic study

Human organic cation transporter ( and ) gene polymorphisms and therapeutic effects of metformin

Establishment of an experimental rat model of tacrolimus-induced kidney injury accompanied by interstitial fibrosis

Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP

Involvement of Organic Cation Transporters in the Kinetics of Trimethylamine N-oxide

What Are Barriers to Pharmacogenomics (PGx) Clinical Uptake?

Population Pharmacokinetic and Pharmacodynamic Analysis of Linezolid and a Hematologic Side Effect, Thrombocytopenia, in Japanese Patients

Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers

Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP

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