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Efficient variance components analysis across millions of genomes

Nature communications, 2020-08, Vol.11 (1), p.4020-4020, Article 4020

2020

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Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification

Nature genetics, 2022-01, Vol.54 (1), p.30-39

2022

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Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization

Nature communications, 2021-07, Vol.12 (1), p.4569-11, Article 4569

2021

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Optimized design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis

Nature communications, 2020-10, Vol.11 (1), p.5504-5504, Article 5504

2020

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Estimation of regional polygenicity from GWAS provides insights into the genetic architecture of complex traits

PLoS computational biology, 2021-10, Vol.17 (10), p.e1009483-e1009483

2021

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Additional impact of genetic ancestry over race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer

HGG advances, 2024-07, Vol.5 (3), p.100320, Article 100320

2024

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Powerful eQTL mapping through low-coverage RNA sequencing

HGG advances, 2022-07, Vol.3 (3), p.100103, Article 100103

2022

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Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture

Nature genetics, 2019-08, Vol.51 (8), p.1244-1251

2019

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Genetic Mapping, Inference and Prediction Across Diverse Human Populations

Hou, Kangcheng

2024

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Polygenic scoring accuracy varies across the genetic ancestry continuum

Nature (London), 2023-06, Vol.618 (7966), p.774-781

2023

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Calibrated prediction intervals for polygenic scores across diverse contexts

Nature genetics, 2024-07, Vol.56 (7), p.1386-1396

2024

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Genotype error due to low-coverage sequencing induces uncertainty in polygenic scoring

American journal of human genetics, 2023-08, Vol.110 (8), p.1319-1329

2023

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On powerful GWAS in admixed populations

Nature genetics, 2021-12, Vol.53 (12), p.1631-1633

2021

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CaricatureShop: Personalized and Photorealistic Caricature Sketching

IEEE transactions on visualization and computer graphics, 2020-07, Vol.26 (7), p.2349-2361

2020

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Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data

Nature genetics, 2022-10, Vol.54 (10), p.1572-1580

2022

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Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes

American journal of human genetics, 2022-04, Vol.109 (4), p.692-709

2022

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A multi-dimensional integrative scoring framework for predicting functional variants in the human genome

American journal of human genetics, 2022-03, Vol.109 (3), p.446-456

2022

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Impact of cross-ancestry genetic architecture on GWASs in admixed populations

American journal of human genetics, 2023-06, Vol.110 (6), p.927-939

2023

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Cell-type deconvolution of bulk-blood RNA-seq reveals biological insights into neuropsychiatric disorders

American journal of human genetics, 2024-02, Vol.111 (2), p.323-337

2024

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Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms

Science (American Association for the Advancement of Science), 2024-05, Vol.384 (6698), p.eadh7688

2024

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Integrative analyses identify genes and their functional consequences underlying COVID-19 hospitalization

Molecular genetics and metabolism, 2021-04, Vol.132, p.S215-S215

2021

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OP335 - Integrative analyses identify genes and their functional consequences underlying COVID-19 hospitalization

Molecular genetics and metabolism, 2021-04, Vol.132, p.S215-S215

2021

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Additional impact of genetic ancestry over self-reported race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer

HGG advances, 2024-06, p.100320

2024

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Abstract 2151: Additional impact of genetic ancestry over self-reported race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.2151-2151

2024

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Efficient variance components analysis across millions of genomes

Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification

Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization

Optimized design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis

Estimation of regional polygenicity from GWAS provides insights into the genetic architecture of complex traits

Additional impact of genetic ancestry over race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer

Powerful eQTL mapping through low-coverage RNA sequencing

Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture

Genetic Mapping, Inference and Prediction Across Diverse Human Populations

Polygenic scoring accuracy varies across the genetic ancestry continuum

Calibrated prediction intervals for polygenic scores across diverse contexts

Genotype error due to low-coverage sequencing induces uncertainty in polygenic scoring

On powerful GWAS in admixed populations

CaricatureShop: Personalized and Photorealistic Caricature Sketching

Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data

Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes

A multi-dimensional integrative scoring framework for predicting functional variants in the human genome

Impact of cross-ancestry genetic architecture on GWASs in admixed populations

Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals

Cell-type deconvolution of bulk-blood RNA-seq reveals biological insights into neuropsychiatric disorders

Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms

Integrative analyses identify genes and their functional consequences underlying COVID-19 hospitalization

OP335 - Integrative analyses identify genes and their functional consequences underlying COVID-19 hospitalization

Additional impact of genetic ancestry over self-reported race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer

Abstract 2151: Additional impact of genetic ancestry over self-reported race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer

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