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Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy

PloS one, 2013-12, Vol.8 (12), p.e82562-e82562

2013

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The antimicrobial potential of Streptomyces from insect microbiomes

Nature communications, 2019-01, Vol.10 (1), p.516-516, Article 516

2019

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Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening

Journal of chemical information and modeling, 2017-07, Vol.57 (7), p.1579-1590

2017

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Smad3 Induces Atrogin-1, Inhibits mTOR and Protein Synthesis, and Promotes Muscle Atrophy In Vivo

Molecular endocrinology (Baltimore, Md.), 2013-11, Vol.27 (11), p.1946-1957

2013

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The Transformer database: biotransformation of xenobiotics

Nucleic acids research, 2014-01, Vol.42 (Database issue), p.D1113-D1117

2014

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Predicting kinase inhibitors using bioactivity matrix derived informer sets

PLoS computational biology, 2019-08, Vol.15 (8), p.e1006813-e1006813

2019

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Enhancing the Anticancer Properties of Cardiac Glycosides by Neoglycorandomization

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (35), p.12305-12310

2005

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Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1

PloS one, 2010-11, Vol.5 (11), p.e15511

2010

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A cell-based screening system for influenza A viral RNA transcription/replication inhibitors

Scientific reports, 2013-01, Vol.3 (1), p.1106-1106, Article 1106

2013

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Lactimidomycin, Iso-migrastatin and Related Glutarimide-Containing 12-Membered Macrolides Are Extremely Potent Inhibitors of Cell Migration

Journal of the American Chemical Society, 2009-02, Vol.131 (4), p.1370-1371

2009

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High-throughput screening identifies idarubicin as a preferential inhibitor of smooth muscle versus endothelial cell proliferation

PloS one, 2014-02, Vol.9 (2), p.e89349-e89349

2014

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Drug cocktail optimization in chemotherapy of cancer

PloS one, 2012-12, Vol.7 (12), p.e51020

2012

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Smad4 Cooperates with Lymphoid Enhancer-Binding Factor 1/T Cell-Specific Factor to Increase c-myc Expression in the Absence of TGF-β Signaling

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (49), p.18580-18585

2006

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Androgen Receptor Requires JunD as a Coactivator to Switch on an Oxidative Stress Generation Pathway in Prostate Cancer Cells

Cancer research (Chicago, Ill.), 2010-06, Vol.70 (11), p.4560-4568

2010

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Quantitative microtiter fibronectin fibrillogenesis assay: use in high throughput screening for identification of inhibitor compounds

Matrix biology, 2012-07, Vol.31 (6), p.360-367

2012

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Practical Model Selection for Prospective Virtual Screening

Journal of chemical information and modeling, 2019-01, Vol.59 (1), p.282-293

2019

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Identification and characterization of a novel estrogenic ligand actinopolymorphol A

Biochemical pharmacology, 2010-10, Vol.80 (8), p.1221-1229

2010

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Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression

PloS one, 2011-09, Vol.6 (9), p.e25021-e25021

2011

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A High-Throughput Method to Identify Novel Senescence-Inducing Compounds

Journal of biomolecular screening, 2009-08, Vol.14 (7), p.853-858

2009

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Evaluating Scalable Supervised Learning for Synthesize-on-Demand Chemical Libraries

Journal of chemical information and modeling, 2023-09, Vol.63 (17), p.5513-5528

2023

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Thalassosamide, a Siderophore Discovered from the Marine-Derived Bacterium Thalassospira profundimaris

Journal of natural products (Washington, D.C.), 2017-09, Vol.80 (9), p.2551-2555

2017

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Identification of idarubicin in high throughput screen as a drug that selectively inhibits the proliferation of human smooth muscle cells versus endothelial cells

Journal of the American College of Surgeons, 2013-09, Vol.217 (3), p.S160-S161

2013

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Biemamides A–E, Inhibitors of the TGF‑β Pathway That Block the Epithelial to Mesenchymal Transition

Organic letters, 2018-09, Vol.20 (18), p.5529-5532

2018

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MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (20), p.9954-9962

2007

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Inhibition of Transforming Growth Factor-β1–induced Signaling and Epithelial-to-Mesenchymal Transition by the Smad-binding Peptide Aptamer Trx-SARA

Molecular biology of the cell, 2006-09, Vol.17 (9), p.3819-3831

2006

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Polymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapy

The antimicrobial potential of Streptomyces from insect microbiomes

Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening

Smad3 Induces Atrogin-1, Inhibits mTOR and Protein Synthesis, and Promotes Muscle Atrophy In Vivo

The Transformer database: biotransformation of xenobiotics

Predicting kinase inhibitors using bioactivity matrix derived informer sets

Enhancing the Anticancer Properties of Cardiac Glycosides by Neoglycorandomization

Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1

A cell-based screening system for influenza A viral RNA transcription/replication inhibitors

Lactimidomycin, Iso-migrastatin and Related Glutarimide-Containing 12-Membered Macrolides Are Extremely Potent Inhibitors of Cell Migration

High-throughput screening identifies idarubicin as a preferential inhibitor of smooth muscle versus endothelial cell proliferation

Drug cocktail optimization in chemotherapy of cancer

Smad4 Cooperates with Lymphoid Enhancer-Binding Factor 1/T Cell-Specific Factor to Increase c-myc Expression in the Absence of TGF-β Signaling

Androgen Receptor Requires JunD as a Coactivator to Switch on an Oxidative Stress Generation Pathway in Prostate Cancer Cells

Quantitative microtiter fibronectin fibrillogenesis assay: use in high throughput screening for identification of inhibitor compounds

Practical Model Selection for Prospective Virtual Screening

Identification and characterization of a novel estrogenic ligand actinopolymorphol A

Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression

A High-Throughput Method to Identify Novel Senescence-Inducing Compounds

Evaluating Scalable Supervised Learning for Synthesize-on-Demand Chemical Libraries

Thalassosamide, a Siderophore Discovered from the Marine-Derived Bacterium Thalassospira profundimaris

Identification of idarubicin in high throughput screen as a drug that selectively inhibits the proliferation of human smooth muscle cells versus endothelial cells

Biemamides A–E, Inhibitors of the TGF‑β Pathway That Block the Epithelial to Mesenchymal Transition

MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines

Inhibition of Transforming Growth Factor-β1–induced Signaling and Epithelial-to-Mesenchymal Transition by the Smad-binding Peptide Aptamer Trx-SARA

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