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A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

Nature communications, 2017-11, Vol.8 (1), p.1741-13, Article 1741

2017

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TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition

eLife, 2018-01, Vol.7

2018

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Structural studies of the TGF-βs and their receptors – insights into evolution of the TGF-β superfamily

FEBS letters, 2012-07, Vol.586 (14), p.1860-1870

Hinck, Andrew P.

2012

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Ternary Complex of Transforming Growth Factor-β1 Reveals Isoform-specific Ligand Recognition and Receptor Recruitment in the Superfamily

The Journal of biological chemistry, 2010-05, Vol.285 (19), p.14806-14814

2010

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Structural basis for potency differences between GDF8 and GDF11

BMC biology, 2017-03, Vol.15 (1), p.19-19, Article 19

2017

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On ‘Deuterium exchange of poly-dl-alanine in aqueous solution’ by Arieh Berger and K. Linderstrøm-Lang

Archives of biochemistry and biophysics, 2022-09, Vol.726, p.109185-109185, Article 109185

Hinck, Andrew P.

2022

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Shear Stress and Sub-Femtomolar Levels of Ligand Synergize to Activate ALK1 Signaling in Endothelial Cells

Cells (Basel, Switzerland), 2024-02, Vol.13 (3), p.285

2024

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Betaglycan sustains HGF/Met signaling in lung cancer and endothelial cells promoting cell migration and tumor growth

Heliyon, 2024-05, Vol.10 (9), p.e30520-e30520, Article e30520

2024

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Structure and Role of BCOR PUFD in Noncanonical PRC1 Assembly and Disease

Biochemistry (Easton), 2020-07, Vol.59 (29), p.2718-2728

2020

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Structural Basis of J Cochaperone Binding and Regulation of Hsp70

Molecular cell, 2007-11, Vol.28 (3), p.422-433

2007

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Structural Biology and Evolution of the TGF-β Family

Cold Spring Harbor perspectives in biology, 2016-12, Vol.8 (12), p.a022103

2016

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TGFβ+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro‐angiogenic phenotype

Journal of extracellular vesicles, 2022-12, Vol.11 (12), p.e12294-n/a

2022

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ALK1 signaling in development and disease: new paradigms

Cellular and molecular life sciences : CMLS, 2017-12, Vol.74 (24), p.4539-4560

2017

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Synthesis of 13 C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells

Organic & biomolecular chemistry, 2023-11, Vol.21 (46), p.9216-9229

2023

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Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family

Experimental Biology and Medicine, 2019-12, Vol.244 (17), p.1547-1558

2019

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Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED

Nature methods, 2017-02, Vol.14 (4), p.399

2017

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Structure-guided engineering of TGF-βs for the development of novel inhibitors and probing mechanism

Bioorganic & medicinal chemistry, 2018-10, Vol.26 (19), p.5239-5246

Hinck, Andrew P.

2018

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TGF-β Antagonists: Same Knot, but Different Hold

Structure (London), 2013-08, Vol.21 (8), p.1269-1270

2013

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Synthesis of C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells

Organic & biomolecular chemistry, 2023-11, Vol.21 (46), p.9216-9229

2023

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Synthesis of 13C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells

Organic & biomolecular chemistry, 2023-11, Vol.21 (46), p.9216-9229

2023

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Computational modeling of TGF-β2:TβRI:TβRII receptor complex assembly as mediated by the TGF-β coreceptor betaglycan

Biophysical journal, 2023-04, Vol.122 (7), p.1342-1354

2023

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Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain

Structure (London), 2010-08, Vol.18 (8), p.966-975

2010

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Structures of TGF-β receptor complexes: implications for function and therapeutic intervention using ligand traps

Current pharmaceutical biotechnology, 2011-12, Vol.12 (12), p.2081

2011

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The Growth-Suppressive Function of the Polycomb Group Protein Polyhomeotic Is Mediated by Polymerization of Its Sterile Alpha Motif (SAM) Domain

The Journal of biological chemistry, 2012-03, Vol.287 (12), p.8702-8713

2012

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Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-β to its receptors, TβRI and TβRII

The Journal of biological chemistry, 2022-06, Vol.298 (6), p.101994-101994, Article 101994

2022

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A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition

Structural studies of the TGF-βs and their receptors – insights into evolution of the TGF-β superfamily

Ternary Complex of Transforming Growth Factor-β1 Reveals Isoform-specific Ligand Recognition and Receptor Recruitment in the Superfamily

Structural basis for potency differences between GDF8 and GDF11

On ‘Deuterium exchange of poly-dl-alanine in aqueous solution’ by Arieh Berger and K. Linderstrøm-Lang

Shear Stress and Sub-Femtomolar Levels of Ligand Synergize to Activate ALK1 Signaling in Endothelial Cells

Betaglycan sustains HGF/Met signaling in lung cancer and endothelial cells promoting cell migration and tumor growth

Structure and Role of BCOR PUFD in Noncanonical PRC1 Assembly and Disease

Structural Basis of J Cochaperone Binding and Regulation of Hsp70

Structural Biology and Evolution of the TGF-β Family

TGFβ+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro‐angiogenic phenotype

ALK1 signaling in development and disease: new paradigms

Synthesis of 13 C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells

Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family

Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED

Structure-guided engineering of TGF-βs for the development of novel inhibitors and probing mechanism

TGF-β Antagonists: Same Knot, but Different Hold

Synthesis of C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells

Synthesis of 13C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells

Computational modeling of TGF-β2:TβRI:TβRII receptor complex assembly as mediated by the TGF-β coreceptor betaglycan

Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain

Structures of TGF-β receptor complexes: implications for function and therapeutic intervention using ligand traps

The Growth-Suppressive Function of the Polycomb Group Protein Polyhomeotic Is Mediated by Polymerization of Its Sterile Alpha Motif (SAM) Domain

Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-β to its receptors, TβRI and TβRII

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