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Immunogenicity and toxicity of AAV gene therapy

Frontiers in immunology, 2022-08, Vol.13

Ertl, Hildegund C. J.

2022

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The Natural Stilbenoid (–)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants

Antimicrobial agents and chemotherapy, 2021-11, Vol.65 (12), p.e0077221-e0077221

2021

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The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver

Blood, 2011-06, Vol.117 (24), p.6459-6468

2011

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T Cell-Mediated Immune Responses to AAV and AAV Vectors

Frontiers in immunology, 2021-04, Vol.12, p.666666-666666

Ertl, Hildegund C J

2021

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Effect of Preexisting Immunity to Adenovirus Human Serotype 5 Antigens on the Immune Responses of Nonhuman Primates to Vaccine Regimens Based on Human- or Chimpanzee-Derived Adenovirus Vectors

Journal of Virology, 2007-06, Vol.81 (12), p.6594-6604

2007

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Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

Cancer cell, 2017-09, Vol.32 (3), p.377-391.e9

2017

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Immune response to influenza vaccination in the elderly is altered by chronic medication use

Immunity & ageing, 2018-08, Vol.15 (1), p.19-19, Article 19

2018

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Preclinical Immunogenicity and Efficacy Studies for Therapeutic Vaccines for Human Papillomavirus-Type-16-Associated Cancer

Vaccines (Basel), 2024-06, Vol.12 (6), p.616

2024

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Hepatitis B virus polymerase-specific T cell epitopes shift in a mouse model of chronic infection

Virology journal, 2021-12, Vol.18 (1), p.242-242, Article 242

2021

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COVID-19 Vaccines Based on Adenovirus Vectors

Trends in biochemical sciences (Amsterdam. Regular ed.), 2021-05, Vol.46 (5), p.429-430

2021

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Activated CD4⁺CCR5⁺ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques

Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (2), p.518-523

2015

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Adenovirus-specific human T cells are pervasive, polyfunctional, and cross-reactive

Vaccine, 2010-02, Vol.28 (8), p.1932-1941

2010

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Considerations for the Clinical Application of Chimeric Antigen Receptor T Cells: Observations from a Recombinant DNA Advisory Committee Symposium Held June 15, 2010

Cancer research (Chicago, Ill.), 2011-05, Vol.71 (9), p.3175-3181

2011

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Impact of AAV Capsid-Specific T-Cell Responses on Design and Outcome of Clinical Gene Transfer Trials with Recombinant Adeno-Associated Viral Vectors: An Evolving Controversy

Human gene therapy, 2017-04, Vol.28 (4), p.328-337

2017

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Novel vaccines to human rabies

PLoS neglected tropical diseases, 2009-09, Vol.3 (9), p.e515-e515

2009

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Structure-Based Identification of a Major Neutralizing Site in an Adenovirus Hexon

Journal of Virology, 2007-02, Vol.81 (4), p.1680-1689

2007

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New Insights on Adenovirus as Vaccine Vectors

Molecular therapy, 2009-08, Vol.17 (8), p.1333-1339

2009

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New human rabies vaccines in the pipeline

Vaccine, 2019-10, Vol.37 (Suppl 1), p.A140-A145

2019

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Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B

Journal of translational medicine, 2014-01, Vol.12 (1), p.25-25, Article 25

2014

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Effect of Preexisting Immunity on an Adenovirus Vaccine Vector: In Vitro Neutralization Assays Fail To Predict Inhibition by Antiviral Antibody In Vivo

Journal of Virology, 2009-06, Vol.83 (11), p.5567-5573

2009

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Impact of the Underlying Mutation and the Route of Vector Administration on Immune Responses to Factor IX in Gene Therapy for Hemophilia B

Molecular therapy, 2009-10, Vol.17 (10), p.1733-1742

2009

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New Rabies Vaccines for Use in Humans

Vaccines (Basel), 2019-06, Vol.7 (2), p.54

Ertl, Hildegund C J

2019

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Management of Rabies in Humans

Clinical infectious diseases, 2003-01, Vol.36 (1), p.60-63

2003

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Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors

Vaccine, 2009-09, Vol.27 (42), p.5837-5845

2009

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Immunogenicity and toxicity of AAV gene therapy

The Natural Stilbenoid (–)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants

The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver

T Cell-Mediated Immune Responses to AAV and AAV Vectors

Effect of Preexisting Immunity to Adenovirus Human Serotype 5 Antigens on the Immune Responses of Nonhuman Primates to Vaccine Regimens Based on Human- or Chimpanzee-Derived Adenovirus Vectors

Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

Immune response to influenza vaccination in the elderly is altered by chronic medication use

Preclinical Immunogenicity and Efficacy Studies for Therapeutic Vaccines for Human Papillomavirus-Type-16-Associated Cancer

Hepatitis B virus polymerase-specific T cell epitopes shift in a mouse model of chronic infection

COVID-19 Vaccines Based on Adenovirus Vectors

Activated CD4⁺CCR5⁺ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques

Adenovirus-specific human T cells are pervasive, polyfunctional, and cross-reactive

Considerations for the Clinical Application of Chimeric Antigen Receptor T Cells: Observations from a Recombinant DNA Advisory Committee Symposium Held June 15, 2010

Impact of AAV Capsid-Specific T-Cell Responses on Design and Outcome of Clinical Gene Transfer Trials with Recombinant Adeno-Associated Viral Vectors: An Evolving Controversy

Novel vaccines to human rabies

Structure-Based Identification of a Major Neutralizing Site in an Adenovirus Hexon

PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine

New Insights on Adenovirus as Vaccine Vectors

New human rabies vaccines in the pipeline

Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B

Effect of Preexisting Immunity on an Adenovirus Vaccine Vector: In Vitro Neutralization Assays Fail To Predict Inhibition by Antiviral Antibody In Vivo

Impact of the Underlying Mutation and the Route of Vector Administration on Immune Responses to Factor IX in Gene Therapy for Hemophilia B

New Rabies Vaccines for Use in Humans

Management of Rabies in Humans

Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors

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