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Development of UHPLC/Q-TOF Analysis Method to Screen Glycerin for Direct Detection of Process Contaminants 3-Monochloropropane-1,2-diol Esters (3-MCPDEs) and Glycidyl Esters (GEs)

Molecules (Basel, Switzerland), 2021-04, Vol.26 (9), p.2449

2021

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Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad-Spectrum Antibiotic Activity

Angewandte Chemie (International ed.), 2007-01, Vol.46 (25), p.4684-4688

2007

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Ketohexokinase knockout mice, a model for essential fructosuria, exhibit altered fructose metabolism and are protected from diet-induced metabolic defects

American journal of physiology: endocrinology and metabolism, 2018-09, Vol.315 (3), p.E386-E393

2018

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Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy

Journal of the American Chemical Society, 2006-09, Vol.128 (36), p.11916-11920

2006

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Rapid, Selective, and Sensitive Method for Semitargeted Discovery of Congeneric Natural Products by Liquid Chromatography Tandem Mass Spectrometry

Journal of natural products (Washington, D.C.), 2021-03, Vol.84 (3), p.814-823

2021

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Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (18), p.7612-7616

2007

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Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey[S]

Journal of lipid research, 2016-12, Vol.57 (12), p.2150-2162

2016

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Enhanced data-independent analysis of lipids using ion mobility-TOFMSE to unravel quantitative and qualitative information in human plasma

Rapid communications in mass spectrometry, 2013-10, Vol.27 (19), p.2195-2200

2013

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Glucagon receptor antagonism induces increased cholesterol absorption[S]

Journal of lipid research, 2015-11, Vol.56 (11), p.2183-2195

2015

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Discovery of a Small Molecule That Inhibits Cell Division by Blocking FtsZ, a Novel Therapeutic Target of Antibiotics

The Journal of biological chemistry, 2003-11, Vol.278 (45), p.44424-44428

2003

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Biosynthetic Studies of Platensimycin

Journal of the American Chemical Society, 2007-12, Vol.129 (50), p.15422-15423

2007

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The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

PloS one, 2016-10, Vol.11 (10), p.e0164133-e0164133

2016

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Circumambulatory Movement of Negative Charge (“Ring Walk”) during Gas-Phase Dissociation of 2,3,4-Trimethoxybenzoate Anion

Journal of organic chemistry, 2014-05, Vol.79 (10), p.4378-4389

2014

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Discovery of FabH/FabF Inhibitors from Natural Products

Antimicrobial Agents and Chemotherapy, 2006-02, Vol.50 (2), p.519-526

2006

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Chemistry of platensimycin

Tetrahedron letters, 2007-07, Vol.48 (31), p.5429-5433

2007

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Determination of Selectivity and Efficacy of Fatty Acid Synthesis Inhibitors

The Journal of biological chemistry, 2005-01, Vol.280 (2), p.1669-1677

2005

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Platensimycin and Platencin Congeners from Streptomyces platensis

Journal of natural products (Washington, D.C.), 2011-03, Vol.74 (3), p.329-340

2011

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Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice[S]

Journal of lipid research, 2013-10, Vol.54 (10), p.2615-2622

2013

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Structure and Semisynthesis of Platensimide A, Produced by Streptomyces platensis

Organic letters, 2008-05, Vol.10 (9), p.1699-1702

2008

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Correction: The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

PloS one, 2017-01, Vol.12 (1), p.e0170721-e0170721

2017

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Isolation, enzyme-bound structure and antibacterial activity of platencin from Streptomyces platensis

Bioorganic & medicinal chemistry letters, 2010-09, Vol.19 (16), p.4756-4759

2010

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In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS[S]

Journal of lipid research, 2011-01, Vol.52 (1), p.159-169

2011

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Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (16), p.4756-4759

2009

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Structure of homoplatensimide A: a potential key biosynthetic intermediate of platensimycin isolated from Streptomyces platensis

Tetrahedron letters, 2008-05, Vol.49 (22), p.3648-3651

2008

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Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water

Journal of lipid research, 2012-06, Vol.53 (6), p.1223-1231

2012

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Development of UHPLC/Q-TOF Analysis Method to Screen Glycerin for Direct Detection of Process Contaminants 3-Monochloropropane-1,2-diol Esters (3-MCPDEs) and Glycidyl Esters (GEs)

Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad-Spectrum Antibiotic Activity

Ketohexokinase knockout mice, a model for essential fructosuria, exhibit altered fructose metabolism and are protected from diet-induced metabolic defects

Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy

Rapid, Selective, and Sensitive Method for Semitargeted Discovery of Congeneric Natural Products by Liquid Chromatography Tandem Mass Spectrometry

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey[S]

Enhanced data-independent analysis of lipids using ion mobility-TOFMSE to unravel quantitative and qualitative information in human plasma

Glucagon receptor antagonism induces increased cholesterol absorption[S]

Discovery of a Small Molecule That Inhibits Cell Division by Blocking FtsZ, a Novel Therapeutic Target of Antibiotics

Biosynthetic Studies of Platensimycin

The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

Circumambulatory Movement of Negative Charge (“Ring Walk”) during Gas-Phase Dissociation of 2,3,4-Trimethoxybenzoate Anion

Discovery of FabH/FabF Inhibitors from Natural Products

Chemistry of platensimycin

Determination of Selectivity and Efficacy of Fatty Acid Synthesis Inhibitors

Platensimycin and Platencin Congeners from Streptomyces platensis

Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice[S]

Structure and Semisynthesis of Platensimide A, Produced by Streptomyces platensis

Correction: The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

Isolation, enzyme-bound structure and antibacterial activity of platencin from Streptomyces platensis

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS[S]

Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis

Structure of homoplatensimide A: a potential key biosynthetic intermediate of platensimycin isolated from Streptomyces platensis

Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water

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