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Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes

Diabetes, obesity & metabolism, 2013-09, Vol.15 (9), p.853-862

2013

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A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus

Diabetologia, 2013-02, Vol.56 (2), p.259-267

2013

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Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with Type 2 diabetes mellitus

Diabetic medicine, 2014-09, Vol.31 (9), p.1138-1147

2014

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Effects of Direct Renin Blockade on Renal & Systemic Hemodynamics and on RAAS Activity, in Weight Excess and Hypertension: A Randomized Clinical Trial

PloS one, 2017-01, Vol.12 (1), p.e0169258-e0169258

2017

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Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial

Diabetologia, 2011-01, Vol.54 (1), p.44-50

2011

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Predictors of mortality in hospital survivors with type 2 diabetes mellitus and acute coronary syndromes

Diabetes & vascular disease research, 2018-01, Vol.15 (1), p.14-23

2018

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Early renin-angiotensin system intervention is more beneficial than late intervention in delaying end-stage renal disease in patients with type 2 diabetes

Diabetes, obesity & metabolism, 2016-01, Vol.18 (1), p.64-71

2016

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A prediction of the renal and cardiovascular efficacy of aliskiren in ALTITUDE using short-term changes in multiple risk markers

European journal of preventive cardiology, 2014-04, Vol.21 (4), p.434-441

2014

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Predictors of response in initial users of metformin and sulphonylurea derivatives: a systematic review

Diabetic medicine, 2015-07, Vol.32 (7), p.853-864

2015

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Validity of biomarkers predicting onset or progression of nephropathy in patients with Type 2 diabetes: a systematic review

Diabetic medicine, 2012-05, Vol.29 (5), p.567-577

2012

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Modeling and simulation for medical product development and evaluation: highlights from the FDA-C-Path-ISOP 2013 workshop

Journal of pharmacokinetics and pharmacodynamics, 2014-12, Vol.41 (6), p.545-552

2014

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High serum potassium levels after losartan can reflect more severe renal disease. Reply to Gonçalves AR, El Nahas AM [letter]

Diabetologia, 2011-11, Vol.54 (11), p.2965-2967

2011

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Dual RAS Therapy Not on Target, but Fully Alive

Nephron, 2010-09, Vol.116 (2), p.c137-c142

2010

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Alkalinization of urine samples preserves albumin concentrations during prolonged frozen storage in patients with diabetes mellitus

Diabetic medicine, 2009-05, Vol.26 (5), p.556-559

2009

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Rationale for and study design of the sulodexide trials in Type 2 diabetic, hypertensive patients with microalbuminuria or overt nephropathy

Diabetic medicine, 2007-11, Vol.24 (11), p.1290-1295

2007

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Is Doubling of Serum Creatinine a Valid Clinical ‘Hard’ Endpoint in Clinical Nephrology Trials?

Nephron, 2011-10, Vol.119 (3), p.c195-c199

2011

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Erratum to: Abstracts of the 51st Annual Meeting of the EASD, Stockholm 2015. ‘Dapagliflozin reduces albuminuria on top of renin-angiotensin system blockade in hypertensive patients with diabetes’

Diabetologia, 2015-12, Vol.58 (12), p.2901-2901

2015

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The Importance of Short-Term Off-Target Effects in Estimating the Long-Term Renal and Cardiovascular Protection of Angiotensin Receptor Blockers

Clinical pharmacology and therapeutics, 2014-02, Vol.95 (2), p.208-215

2014

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Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis

The Lancet (British edition), 2012, Vol.380 (9854), p.1662-1673

2012

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Inhibition of the Renin-Angiotensin-Aldosterone System for Cerebrorenal Protection

Brain, Stroke and Kidney, 2013, Vol.179, p.7-14

2013

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Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial

BMJ (British Medical Journal), 2011-07, Vol.343 (7818), p.d4366-298

International edition, 2011

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The Selective Vitamin D Receptor Activator for Albuminuria Lowering (VITAL) Study: Study Design and Baseline Characteristics

American journal of nephrology, 2009-01, Vol.30 (3), p.280-286

2009

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Albuminuria Assessed From First-Morning-Void Urine Samples Versus 24-Hour Urine Collections as a Predictor of Cardiovascular Morbidity and Mortality

American journal of epidemiology, 2008-10, Vol.168 (8), p.897-905

2008

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Salt intake in kidney disease—a missed therapeutic opportunity?

Nephrology, dialysis, transplantation, 2012-09, Vol.27 (9), p.3435-3442

2012

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Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts

Kidney international, 2011-06, Vol.79 (12), p.1331-1340

2011

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Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes

A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus

Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with Type 2 diabetes mellitus

Effects of Direct Renin Blockade on Renal & Systemic Hemodynamics and on RAAS Activity, in Weight Excess and Hypertension: A Randomized Clinical Trial

Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial

Predictors of mortality in hospital survivors with type 2 diabetes mellitus and acute coronary syndromes

Early renin-angiotensin system intervention is more beneficial than late intervention in delaying end-stage renal disease in patients with type 2 diabetes

A prediction of the renal and cardiovascular efficacy of aliskiren in ALTITUDE using short-term changes in multiple risk markers

Predictors of response in initial users of metformin and sulphonylurea derivatives: a systematic review

Validity of biomarkers predicting onset or progression of nephropathy in patients with Type 2 diabetes: a systematic review

Modeling and simulation for medical product development and evaluation: highlights from the FDA-C-Path-ISOP 2013 workshop

High serum potassium levels after losartan can reflect more severe renal disease. Reply to Gonçalves AR, El Nahas AM [letter]

Dual RAS Therapy Not on Target, but Fully Alive

Alkalinization of urine samples preserves albumin concentrations during prolonged frozen storage in patients with diabetes mellitus

Rationale for and study design of the sulodexide trials in Type 2 diabetic, hypertensive patients with microalbuminuria or overt nephropathy

Is Doubling of Serum Creatinine a Valid Clinical ‘Hard’ Endpoint in Clinical Nephrology Trials?

Erratum to: Abstracts of the 51st Annual Meeting of the EASD, Stockholm 2015. ‘Dapagliflozin reduces albuminuria on top of renin-angiotensin system blockade in hypertensive patients with diabetes’

The Importance of Short-Term Off-Target Effects in Estimating the Long-Term Renal and Cardiovascular Protection of Angiotensin Receptor Blockers

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis

Inhibition of the Renin-Angiotensin-Aldosterone System for Cerebrorenal Protection

Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial

The Selective Vitamin D Receptor Activator for Albuminuria Lowering (VITAL) Study: Study Design and Baseline Characteristics

Albuminuria Assessed From First-Morning-Void Urine Samples Versus 24-Hour Urine Collections as a Predictor of Cardiovascular Morbidity and Mortality

Salt intake in kidney disease—a missed therapeutic opportunity?

Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts

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