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Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack

Angewandte Chemie (International ed.), 2013-03, Vol.52 (10), p.2744-2792

International ed. in English, 2013

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Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b

Nature communications, 2023-04, Vol.14 (1), p.2245-2245, Article 2245

2023

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Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1

Nature communications, 2021-01, Vol.12 (1), p.460-460, Article 460

2021

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Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion‐Dominated Canalicular and Flow‐Augmented Ductular Bile Flux

Hepatology (Baltimore, Md.), 2021-04, Vol.73 (4), p.1531-1550

2021

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Small-molecule inhibition of APT1 affects Ras localization and signaling

Nature chemical biology, 2010-06, Vol.6 (6), p.449

2010

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Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD

Nature communications, 2021-04, Vol.12 (1), p.2426-2426, Article 2426

2021

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Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3

Biochemistry (Easton), 2020-09, Vol.59 (38), p.3570-3581

2020

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Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway

PLoS pathogens, 2015-12, Vol.11 (12), p.e1005307-e1005307

2015

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Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

Angewandte Chemie (International ed.), 2011-10, Vol.50 (42), p.9838-9842

2011

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Synthesis and Spectroscopic Properties of Fluorinated Coumarin Lysine Derivatives

Journal of organic chemistry, 2018-04, Vol.83 (8), p.4792-4799

2018

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Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (21), p.8155-8160

2012

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The Mechanism of Caseinolytic Protease (ClpP) Inhibition

Angewandte Chemie (International ed.), 2013-03, Vol.52 (10), p.3009-3014

International ed. in English, 2013

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Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design

Angewandte Chemie (International ed.), 2011-10, Vol.50 (42), p.9832-9837

International ed. in English, 2011

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Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation

iScience, 2020-12, Vol.23 (12), p.101800-101800, Article 101800

2020

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Biology-Oriented Synthesis of a Tetrahydroisoquinoline-Based Compound Collection Targeting Microtubule Polymerization

Chembiochem : a European journal of chemical biology, 2013-02, Vol.14 (3), p.295-300

2013

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Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation

iScience, 2021-07, Vol.24 (7), p.102731, Article 102731

2021

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Enantioselective Synthesis of the C10–C20 Fragment of Fusicoccin A

Journal of organic chemistry, 2011-08, Vol.76 (16), p.6694-6702

2011

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Exploring anti-bacterial compounds against intracellular Legionella

PloS one, 2013-09, Vol.8 (9), p.e74813

2013

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Modulating effects of acyl-CoA synthetase 5-derived mitochondrial Wnt2B palmitoylation on intestinal Wnt activity

World journal of gastroenterology : WJG, 2014-10, Vol.20 (40), p.14855-14864

2014

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Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern

Molecular and Cellular Biology, 2011-10, Vol.31 (19), p.3938-3952

2011

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Amino Acid Building Blocks for Efficient Fmoc Solid-Phase Synthesis of Peptides Adenylylated at Serine or Threonine

Organic letters, 2011-11, Vol.13 (22), p.6014-6017

2011

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Identifizierung der Zielproteine bioaktiver Verbindungen: Die Suche nach der Nadel im Heuhaufen

Angewandte Chemie, 2013-03, Vol.125 (10), p.2808-2859

2013

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In Vivo Imaging of the Macrophage Migration Inhibitory Factor in Liver Cancer with an Activity-Based Probe

Analytical chemistry (Washington), 2021-02, Vol.93 (4), p.2152-2159

2021

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Boron-Based Inhibitors of Acyl Protein Thioesterases 1 and 2

Chembiochem : a European journal of chemical biology, 2013-01, Vol.14 (1), p.115-122

2013

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Molecular Perspectives on Protein Adenylylation

ACS chemical biology, 2015-01, Vol.10 (1), p.12-21

2015

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Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack

Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b

Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1

Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion‐Dominated Canalicular and Flow‐Augmented Ductular Bile Flux

Small-molecule inhibition of APT1 affects Ras localization and signaling

Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD

Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3

Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

Synthesis and Spectroscopic Properties of Fluorinated Coumarin Lysine Derivatives

Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis

The Mechanism of Caseinolytic Protease (ClpP) Inhibition

Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design

Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation

Biology-Oriented Synthesis of a Tetrahydroisoquinoline-Based Compound Collection Targeting Microtubule Polymerization

Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation

Enantioselective Synthesis of the C10–C20 Fragment of Fusicoccin A

Exploring anti-bacterial compounds against intracellular Legionella

Modulating effects of acyl-CoA synthetase 5-derived mitochondrial Wnt2B palmitoylation on intestinal Wnt activity

Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern

Amino Acid Building Blocks for Efficient Fmoc Solid-Phase Synthesis of Peptides Adenylylated at Serine or Threonine

Identifizierung der Zielproteine bioaktiver Verbindungen: Die Suche nach der Nadel im Heuhaufen

In Vivo Imaging of the Macrophage Migration Inhibitory Factor in Liver Cancer with an Activity-Based Probe

Boron-Based Inhibitors of Acyl Protein Thioesterases 1 and 2

Molecular Perspectives on Protein Adenylylation

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