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Pharmacological brake-release of mRNA translation enhances cognitive memory

eLife, 2013-05, Vol.2, p.e00498-e00498

2013

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Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response

eLife, 2015-04, Vol.4, p.e07314-e07314

2015

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Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch

eLife, 2016-07, Vol.5

2016

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Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6

PloS one, 2012-12, Vol.7 (12), p.e50864-e50864

2012

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USP7 small-molecule inhibitors interfere with ubiquitin binding

Nature (London), 2017-10, Vol.550 (7677), p.534-538

2017

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Biodegradable Tetra-PEG Hydrogels as Carriers for a Releasable Drug Delivery System

Bioconjugate chemistry, 2015-02, Vol.26 (2), p.270-278

2015

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In Vitro-In Vivo Correlation for the Degradation of Tetra-PEG Hydrogel Microspheres with Tunable β-Eliminative Crosslink Cleavage Rates

International journal of polymer science, 2019-01, Vol.2019 (2019), p.1-7

2019

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Predicting and Improving the Membrane Permeability of Peptidic Small Molecules

Journal of medicinal chemistry, 2012-04, Vol.55 (7), p.3163-3169

2012

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PET Imaging of the EPR Effect in Tumor Xenografts Using Small 15 nm Diameter Polyethylene Glycols Labeled with Zirconium-89

Molecular cancer therapeutics, 2020-02, Vol.19 (2), p.673-679

2020

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Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine

ACS chemical biology, 2020-06, Vol.15 (6), p.1392-1400

2020

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Attenuation of the Reaction of Michael Acceptors with Biologically Important Nucleophiles

Bioconjugate chemistry, 2021-04, Vol.32 (4), p.794-800

2021

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Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation

Structure (London), 2018-01, Vol.26 (1), p.72-84.e7

2018

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Primary deuterium kinetic isotope effects prolong drug release and polymer biodegradation in a drug delivery system

Journal of controlled release, 2018-05, Vol.278, p.74-79

2018

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A Hydrogel-Microsphere Drug Delivery System That Supports Once-Monthly Administration of a GLP‑1 Receptor Agonist

ACS chemical biology, 2017-08, Vol.12 (8), p.2107-2116

2017

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Semisynthesis and Cytotoxicity of Hypothemycin Analogues

ChemMedChem, 2007-11, Vol.2 (11), p.1598-1600

2007

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Approach for Half-Life Extension of Small Antibody Fragments That Does Not Affect Tissue Uptake

Bioconjugate chemistry, 2016-10, Vol.27 (10), p.2534-2539

2016

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Broad-Spectrum Allosteric Inhibition of Herpesvirus Proteases

Biochemistry (Easton), 2014-07, Vol.53 (28), p.4648-4660

2014

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Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response

ChemMedChem, 2016-04, Vol.11 (8), p.870-880

2016

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High‐throughput, aseptic production of injectable Tetra‐PEG hydrogel microspheres for delivery of releasable covalently bound drugs

Engineering reports (Hoboken, N.J.), 2020-08, Vol.2 (8), p.n/a

2020

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Tailoring Small Molecules for an Allosteric Site on Procaspase-6

ChemMedChem, 2014-01, Vol.9 (1), p.73-77

2014

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Intramolecular cyclization reactions of unsaturated amino Fischer chromium carbenes forming indoles and quinolines

Tetrahedron, 2003-10, Vol.59 (44), p.8775-8791

2003

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C-15 Thiazol-4-yl Analogues of (E)-9,10-Didehydroepothilone D: Synthesis and Cytotoxicity

Organic letters, 2006-07, Vol.8 (14), p.3057-3059

2006

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Inside Cover: Tailoring Small Molecules for an Allosteric Site on Procaspase-6 (ChemMedChem 1/2014)

ChemMedChem, 2014-01, Vol.9 (1), p.2-2

2014

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A Divergent Approach to the Myriaporones and Tedanolide: Completion of the Carbon Skeleton of Myriaporone 1

Organic letters, 2002-08, Vol.4 (17), p.2953-2955

2002

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Methanolysis Products of Disorazole A1

Journal of natural products (Washington, D.C.), 2006-01, Vol.69 (1), p.148-150

2006

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Pharmacological brake-release of mRNA translation enhances cognitive memory

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response

Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch

Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6

USP7 small-molecule inhibitors interfere with ubiquitin binding

Biodegradable Tetra-PEG Hydrogels as Carriers for a Releasable Drug Delivery System

In Vitro-In Vivo Correlation for the Degradation of Tetra-PEG Hydrogel Microspheres with Tunable β-Eliminative Crosslink Cleavage Rates

Predicting and Improving the Membrane Permeability of Peptidic Small Molecules

PET Imaging of the EPR Effect in Tumor Xenografts Using Small 15 nm Diameter Polyethylene Glycols Labeled with Zirconium-89

Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine

Attenuation of the Reaction of Michael Acceptors with Biologically Important Nucleophiles

Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation

Primary deuterium kinetic isotope effects prolong drug release and polymer biodegradation in a drug delivery system

A Hydrogel-Microsphere Drug Delivery System That Supports Once-Monthly Administration of a GLP‑1 Receptor Agonist

Semisynthesis and Cytotoxicity of Hypothemycin Analogues

Approach for Half-Life Extension of Small Antibody Fragments That Does Not Affect Tissue Uptake

Broad-Spectrum Allosteric Inhibition of Herpesvirus Proteases

Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response

High‐throughput, aseptic production of injectable Tetra‐PEG hydrogel microspheres for delivery of releasable covalently bound drugs

Tailoring Small Molecules for an Allosteric Site on Procaspase-6

Intramolecular cyclization reactions of unsaturated amino Fischer chromium carbenes forming indoles and quinolines

C-15 Thiazol-4-yl Analogues of (E)-9,10-Didehydroepothilone D: Synthesis and Cytotoxicity

Inside Cover: Tailoring Small Molecules for an Allosteric Site on Procaspase-6 (ChemMedChem 1/2014)

A Divergent Approach to the Myriaporones and Tedanolide: Completion of the Carbon Skeleton of Myriaporone 1

Methanolysis Products of Disorazole A1

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