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Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental Lymphangiogenesis

Cell reports (Cambridge), 2019-08, Vol.28 (8), p.2023-2036.e4

2019

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Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach

Molecules (Basel, Switzerland), 2023-03, Vol.28 (7), p.3103

2023

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Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1

PloS one, 2017-03, Vol.12 (3), p.e0173436-e0173436

2017

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Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids

Molecular pharmaceutics, 2017-03, Vol.14 (3), p.566-579

2017

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Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA

Angewandte Chemie (International ed.), 2015-02, Vol.54 (7), p.2179-2184

International ed. in English, 2015

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Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (23), p.10424-10429

2010

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Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (22), p.6979-6984

2015

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Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?

Journal of biomolecular screening, 2013-02, Vol.18 (2), p.147-159

2013

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Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction

Antibiotics (Basel), 2018-02, Vol.7 (1), p.14

2018

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Rapid Elaboration of Fragments into Leads Applied to Bromodomain‑3 Extra-Terminal Domain

Journal of medicinal chemistry, 2023-04, Vol.66 (8), p.5859-5872

2023

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Δ‐Myrtoxin‐Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane‐Disrupting, and Nociceptive Activities

Angewandte Chemie International Edition, 2017-07, Vol.56 (29), p.8495-8499

2017

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Ligand-enhanced expression and in-cell assay of human peroxisome proliferator-activated receptor alpha ligand binding domain

Protein expression and purification, 2010-04, Vol.70 (2), p.260-269

2010

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Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens

The Journal of biological chemistry, 2018-10, Vol.293 (43), p.16559-16571

2018

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IGF-binding proteins – the pieces are falling into place

Trends in endocrinology and metabolism, 2005-07, Vol.16 (5), p.228-234

2005

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Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module

Scientific reports, 2015-08, Vol.5 (1), p.12905-12905, Article 12905

2015

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A ligand-induced structural change in fatty acid–binding protein 1 is associated with potentiation of peroxisome proliferator–activated receptor α agonists

The Journal of biological chemistry, 2019-03, Vol.294 (10), p.3720-3734

2019

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Structure of the Chicken CD3ϵδ/γ Heterodimer and Its Assembly with the αβT Cell Receptor

The Journal of biological chemistry, 2014-03, Vol.289 (12), p.8240-8251

2014

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The Structure of Integrin α1I Domain in Complex with a Collagen-mimetic Peptide

The Journal of biological chemistry, 2013-12, Vol.288 (52), p.36796-36809

2013

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Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site

FEBS letters, 2010-04, Vol.584 (8), p.1455-1462

2010

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Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV‐1 Integrase

ChemMedChem, 2018-08, Vol.13 (15), p.1555-1565

2018

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Binding site for the C-domain of insulin-like growth factor (IGF) binding protein-6 on IGF-II; implications for inhibition of IGF actions

FEBS letters, 2004-06, Vol.568 (1), p.19-22

2004

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Characterization of Two Distinct Modes of Drug Binding to Human Intestinal Fatty Acid Binding Protein

ACS chemical biology, 2014-11, Vol.9 (11), p.2526-2534

2014

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Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding

Journal of molecular endocrinology, 2004-10, Vol.33 (2), p.377-386

2004

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Protein unfolding is essential for cleavage within the α-helix of a model protein substrate by the serine protease, thrombin

Biochimie, 2016-03, Vol.122, p.227-234

2016

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Distinct binding properties of TIAR RRMs and linker region

RNA biology, 2013-04, Vol.10 (4), p.579-589

2013

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Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental Lymphangiogenesis

Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1

Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids

Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA

Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation

Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening

Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?

Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction

Rapid Elaboration of Fragments into Leads Applied to Bromodomain‑3 Extra-Terminal Domain

Δ‐Myrtoxin‐Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane‐Disrupting, and Nociceptive Activities

Ligand-enhanced expression and in-cell assay of human peroxisome proliferator-activated receptor alpha ligand binding domain

Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens

IGF-binding proteins – the pieces are falling into place

Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module

A ligand-induced structural change in fatty acid–binding protein 1 is associated with potentiation of peroxisome proliferator–activated receptor α agonists

Structure of the Chicken CD3ϵδ/γ Heterodimer and Its Assembly with the αβT Cell Receptor

The Structure of Integrin α1I Domain in Complex with a Collagen-mimetic Peptide

Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site

Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV‐1 Integrase

Binding site for the C-domain of insulin-like growth factor (IGF) binding protein-6 on IGF-II; implications for inhibition of IGF actions

Characterization of Two Distinct Modes of Drug Binding to Human Intestinal Fatty Acid Binding Protein

Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding

Protein unfolding is essential for cleavage within the α-helix of a model protein substrate by the serine protease, thrombin

Distinct binding properties of TIAR RRMs and linker region

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