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The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways

Endocrinology (Philadelphia), 2000-12, Vol.141 (12), p.4524-4532

2000

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Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells

British journal of pharmacology, 2008-12, Vol.155 (7), p.1056-1065

2008

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Cellular actions of nociceptin: transduction mechanisms

Peptides (New York, N.Y. : 1980), 2000-07, Vol.21 (7), p.961-967

2000

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Mitogenic signaling via G protein-coupled receptors

Endocrine reviews, 1996-12, Vol.17 (6), p.698-714

1996

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Tetrahydroisoquinolines as MCH-R1 antagonists

Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (18), p.4917-4921

2006

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G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein

Proceedings of the National Academy of Sciences - PNAS, 1995-09, Vol.92 (20), p.9284-9287

1995

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Differential Intracellular Signaling of the GalR1 and GalR2 Galanin Receptor Subtypes

Biochemistry (Easton), 1998-05, Vol.37 (19), p.6711-6717

1998

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Discovery of Orally Efficacious Melanin-Concentrating Hormone Receptor-1 Antagonists as Antiobesity Agents. Synthesis, SAR, and Biological Evaluation of Bicyclo[3.1.0]hexyl Ureas

Journal of medicinal chemistry, 2006-04, Vol.49 (7), p.2294-2310

2006

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Discovery of Bicycloalkyl Urea Melanin Concentrating Hormone Receptor Antagonists: Orally Efficacious Antiobesity Therapeutics

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2274-2277

2005

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Role of c-Src tyrosine kinase in G protein-coupled receptor- and G beta gamma subunit-mediated activation of mitogen-activated protein kinases

The Journal of biological chemistry, 1996-08, Vol.271 (32), p.19443-19450

1996

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Identification and Pharmacological Characterization of a Novel Human Melanin-concentrating Hormone Receptor, MCH-R2

The Journal of biological chemistry, 2001-09, Vol.276 (37), p.34664-34670

2001

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Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor

The Journal of biological chemistry, 1994-06, Vol.269 (22), p.15776-15785

1994

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Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway

The Journal of biological chemistry, 1996-05, Vol.271 (21), p.12133-12136

1996

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Determination of the G beta gamma-binding domain of phosducin. A regulatable modulator of G beta gamma signaling

The Journal of biological chemistry, 1994-11, Vol.269 (47), p.29825-29830

1994

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Diagnosis and Management of Endometrial Polyps: A Critical Review of the Literature

Journal of minimally invasive gynecology, 2011-09, Vol.18 (5), p.569-581

2011

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Cholera toxin and pertussis toxin provoke differential effects of luteinizing hormone release, inositol phosphate production, and gonadotropin-releasing hormone (GnRH) receptor binding in the gonadotrope : evidence for multiple guanyl nucleotide binding proteins in GnRH action

Endocrinology (Philadelphia), 1993-05, Vol.132 (5), p.2124-2130

1993

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G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism

The Journal of biological chemistry, 1996-01, Vol.271 (3), p.1266

1996

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G Subunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor

The Journal of biological chemistry, 1995-07, Vol.270 (28), p.16495

1995

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Protein Kinase C-mediated Gonadotropin-releasing Hormone Receptor Sequestration Is Associated with Uncoupling of Phosphoinositide Hydrolysis

The Journal of biological chemistry, 1989-05, Vol.264 (15), p.8619-8626

1989

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Development of gonadotrope desensitization to gonadotropin-releasing hormone (GnRH) and recovery are not coupled to inositol phosphate production or GnRH receptor number

Endocrinology (Philadelphia), 1992-12, Vol.131 (6), p.2681-2689

1992

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Gonadotropin-releasing hormone-stimulated intracellular Ca2+ fluctuations and luteinizing hormone release can be uncoupled from inositol phosphate production

Endocrinology (Philadelphia), 1992-06, Vol.130 (6), p.3475-3483

1992

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Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway

Nature (London), 1995-08, Vol.376 (6543), p.781-784

1995

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Distinct Pathways of Gi- and Gq-mediated Mitogen-activated Protein Kinase Activation (∗)

The Journal of biological chemistry, 1995-07, Vol.270 (29), p.17148-17153

1995

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Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates Gβγ-mediated signaling

The Journal of biological chemistry, 1994-02, Vol.269 (8), p.6193-6197

1994

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Selection of models for the study of GnRH stimulated gonadotropin release prejudices the assignment of roles for mediators and modulators of hormone action

Molecular and cellular endocrinology, 1992-04, Vol.84 (3), p.C33-C37

1992

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The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways

Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells

Cellular actions of nociceptin: transduction mechanisms

Mitogenic signaling via G protein-coupled receptors

Tetrahydroisoquinolines as MCH-R1 antagonists

G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein

Differential Intracellular Signaling of the GalR1 and GalR2 Galanin Receptor Subtypes

Discovery of Orally Efficacious Melanin-Concentrating Hormone Receptor-1 Antagonists as Antiobesity Agents. Synthesis, SAR, and Biological Evaluation of Bicyclo[3.1.0]hexyl Ureas

Discovery of Bicycloalkyl Urea Melanin Concentrating Hormone Receptor Antagonists: Orally Efficacious Antiobesity Therapeutics

Role of c-Src tyrosine kinase in G protein-coupled receptor- and G beta gamma subunit-mediated activation of mitogen-activated protein kinases

Identification and Pharmacological Characterization of a Novel Human Melanin-concentrating Hormone Receptor, MCH-R2

Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor

Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway

Determination of the G beta gamma-binding domain of phosducin. A regulatable modulator of G beta gamma signaling

Diagnosis and Management of Endometrial Polyps: A Critical Review of the Literature

Cholera toxin and pertussis toxin provoke differential effects of luteinizing hormone release, inositol phosphate production, and gonadotropin-releasing hormone (GnRH) receptor binding in the gonadotrope : evidence for multiple guanyl nucleotide binding proteins in GnRH action

G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism

G Subunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor

Protein Kinase C-mediated Gonadotropin-releasing Hormone Receptor Sequestration Is Associated with Uncoupling of Phosphoinositide Hydrolysis

Development of gonadotrope desensitization to gonadotropin-releasing hormone (GnRH) and recovery are not coupled to inositol phosphate production or GnRH receptor number

Gonadotropin-releasing hormone-stimulated intracellular Ca2+ fluctuations and luteinizing hormone release can be uncoupled from inositol phosphate production

Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway

Distinct Pathways of Gi- and Gq-mediated Mitogen-activated Protein Kinase Activation (∗)

Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates Gβγ-mediated signaling

Selection of models for the study of GnRH stimulated gonadotropin release prejudices the assignment of roles for mediators and modulators of hormone action

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