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Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis

Frontiers in pharmacology, 2017-07, Vol.8, p.461-461

2017

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Elevated expression of activins promotes muscle wasting and cachexia

The FASEB journal, 2014-04, Vol.28 (4), p.1711-1723

2014

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The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

The Journal of cell biology, 2013-10, Vol.203 (2), p.345-357

2013

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Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

The Journal of cell biology, 2012-06, Vol.197 (7), p.997-1008

2012

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Structural basis for potency differences between GDF8 and GDF11

BMC biology, 2017-03, Vol.15 (1), p.19-19, Article 19

2017

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Engineering the Ovarian Hormones Inhibin A and Inhibin B to Enhance Synthesis and Activity

Endocrinology (Philadelphia), 2020-08, Vol.161 (8), p.1

2020

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Molecular characterization of latent GDF8 reveals mechanisms of activation

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (5), p.E866-E875

2018

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TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle Mass

Frontiers in physiology, 2020-11, Vol.11, p.560225-560225

2020

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Two Distinct Regions of Latency-associated Peptide Coordinate Stability of the Latent Transforming Growth Factor-β1 Complex

The Journal of biological chemistry, 2010-05, Vol.285 (22), p.17029-17037

2010

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Hormonal Regulation of Sertoli Cell Micro-RNAs at Spermiation

Endocrinology (Philadelphia), 2011-04, Vol.152 (4), p.1670-1683

2011

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Activin Signaling Regulates Sertoli Cell Differentiation and Function

Endocrinology (Philadelphia), 2012-12, Vol.153 (12), p.6065-6077

2012

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Growth Differentiation Factor 9 Is a Germ Cell Regulator of Sertoli Cell Function

Endocrinology (Philadelphia), 2009-05, Vol.150 (5), p.2481-2490

2009

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Antagonists of activin signaling: mechanisms and potential biological applications

Trends in endocrinology and metabolism, 2005-03, Vol.16 (2), p.73-78

2005

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Species Differences in the Expression and Activity of Bone Morphogenetic Protein 15

Endocrinology (Philadelphia), 2013-02, Vol.154 (2), p.888-899

2013

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Activation of Latent Human GDF9 by a Single Residue Change (Gly391Arg) in the Mature Domain

Endocrinology (Philadelphia), 2012-03, Vol.153 (3), p.1301-1310

2012

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Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (25), p.E2257-E2257

2013

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Cripto Forms a Complex with Activin and Type II Activin Receptors and Can Block Activin Signaling

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (9), p.5193-5198

2003

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Expression of nodal signalling components in cycling human endometrium and in endometrial cancer

Reproductive biology and endocrinology, 2009-10, Vol.7 (1), p.122-122, Article 122

2009

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Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (26), p.E5266-E5275

2017

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Targeting activins and inhibins to treat reproductive disorders and cancer cachexia

Journal of endocrinology, 2023-07, Vol.258 (1)

2023

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Inhibin B Is a More Potent Suppressor of Rat Follicle-Stimulating Hormone Release than Inhibin A in Vitro and in Vivo

Endocrinology (Philadelphia), 2009-10, Vol.150 (10), p.4784-4793

2009

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Suppression of Inhibin A Biological Activity by Alterations in the Binding Site for Betaglycan

The Journal of biological chemistry, 2008-06, Vol.283 (24), p.16743-16751

2008

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New insights into the mechanisms of activin action and inhibition

Molecular and cellular endocrinology, 2012-08, Vol.359 (1-2), p.2-12

2012

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Differential Effects of IL6 and Activin A in the Development of Cancer-Associated Cachexia

Cancer research (Chicago, Ill.), 2016-09, Vol.76 (18), p.5372-5382

2016

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Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality

The Journal of biological chemistry, 2015-09, Vol.290 (39), p.24007-24020

2015

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Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis

Elevated expression of activins promotes muscle wasting and cachexia

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

Structural basis for potency differences between GDF8 and GDF11

Engineering the Ovarian Hormones Inhibin A and Inhibin B to Enhance Synthesis and Activity

Molecular characterization of latent GDF8 reveals mechanisms of activation

TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle Mass

Two Distinct Regions of Latency-associated Peptide Coordinate Stability of the Latent Transforming Growth Factor-β1 Complex

Hormonal Regulation of Sertoli Cell Micro-RNAs at Spermiation

Activin Signaling Regulates Sertoli Cell Differentiation and Function

Growth Differentiation Factor 9 Is a Germ Cell Regulator of Sertoli Cell Function

Antagonists of activin signaling: mechanisms and potential biological applications

Species Differences in the Expression and Activity of Bone Morphogenetic Protein 15

Activation of Latent Human GDF9 by a Single Residue Change (Gly391Arg) in the Mature Domain

Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization

Cripto Forms a Complex with Activin and Type II Activin Receptors and Can Block Activin Signaling

Expression of nodal signalling components in cycling human endometrium and in endometrial cancer

Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease

Targeting activins and inhibins to treat reproductive disorders and cancer cachexia

Inhibin B Is a More Potent Suppressor of Rat Follicle-Stimulating Hormone Release than Inhibin A in Vitro and in Vivo

Suppression of Inhibin A Biological Activity by Alterations in the Binding Site for Betaglycan

New insights into the mechanisms of activin action and inhibition

Differential Effects of IL6 and Activin A in the Development of Cancer-Associated Cachexia

Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality

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