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Discovery of TRPM8 Antagonist (S)‑6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine

Journal of medicinal chemistry, 2018-09, Vol.61 (18), p.8186-8201

2018

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Extracellular Antibody Drug Conjugates Exploiting the Proximity of Two Proteins

Molecular therapy, 2016-10, Vol.24 (10), p.1760-1770

2016

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Design and Preparation of a Potent Series of Hydroxyethylamine Containing β-Secretase Inhibitors That Demonstrate Robust Reduction of Central β-Amyloid

Journal of medicinal chemistry, 2012-11, Vol.55 (21), p.9009-9024

2012

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Unified Total Synthesis of Pteriatoxins and Their Diastereomers

Journal of the American Chemical Society, 2006-06, Vol.128 (23), p.7463-7465

2006

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Design and Synthesis of Potent, Orally Efficacious Hydroxyethylamine Derived β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors

Journal of medicinal chemistry, 2012-11, Vol.55 (21), p.9025-9044

2012

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Stereoselective Synthesis of anti-N-Protected 3-Amino-1,2-epoxides by Nucleophilic Addition to N-tert-Butanesulfinyl Imine of a Glyceraldehyde Synthon

Journal of organic chemistry, 2009-08, Vol.74 (16), p.5975-5982

2009

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A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of β-Secretase

ACS medicinal chemistry letters, 2012-11, Vol.3 (11), p.886-891

2012

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Total Synthesis of the Potent Microtubule-Stabilizing Agent (+)-Discodermolide

Journal of organic chemistry, 2003-08, Vol.68 (17), p.6646-6660

2003

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Total Synthesis of (−)-Discodermolide: An Application of a Chelation-Controlled Alkylation Reaction

Journal of organic chemistry, 1997-09, Vol.62 (18), p.6098-6099

1997

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Abstract 1202: Target identification for a new type of ADC

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1202-1202

2016

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Abstract A125: Antibody targeted steroids for the treatment of cancer

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.A125-A125

2015

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Abstract 2964: An anti-CD20 extracellular antibody-drug conjugate for the treatment of B-cell malignancies

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2964-2964

2016

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An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities

ACS medicinal chemistry letters, 2015-02, Vol.6 (2), p.210-215

2015

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Discrete layers of ordered fullerene C60 molecules in the cocrystal C60.cntdot.CH2I2.cntdot.C6H6: synthesis, crystal structure, and carbon-13 NMR properties

Chemistry of materials, 1992-09, Vol.4 (5), p.1077-1082

1992

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A total synthesis of (-)-discodermolide

Harried, Scott S

1998

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ChemInform Abstract: Stereoselective Synthesis of anti-N-Protected 3-Amino-1,2-epoxides by Nucleophilic Addition to N-tert-Butanesulfinyl Imine of a Glyceraldehyde Synthon

ChemInform, 2010-01, Vol.41 (2), p.no-no

2010

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Discovery of TRPM8 Antagonist (S)‑6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine

Extracellular Antibody Drug Conjugates Exploiting the Proximity of Two Proteins

Design and Preparation of a Potent Series of Hydroxyethylamine Containing β-Secretase Inhibitors That Demonstrate Robust Reduction of Central β-Amyloid

Unified Total Synthesis of Pteriatoxins and Their Diastereomers

Design and Synthesis of Potent, Orally Efficacious Hydroxyethylamine Derived β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors

Stereoselective Synthesis of anti-N-Protected 3-Amino-1,2-epoxides by Nucleophilic Addition to N-tert-Butanesulfinyl Imine of a Glyceraldehyde Synthon

A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of β-Secretase

Total Synthesis of the Potent Microtubule-Stabilizing Agent (+)-Discodermolide

Total Synthesis of (−)-Discodermolide: An Application of a Chelation-Controlled Alkylation Reaction

Abstract 1202: Target identification for a new type of ADC

Abstract A125: Antibody targeted steroids for the treatment of cancer

Abstract 2964: An anti-CD20 extracellular antibody-drug conjugate for the treatment of B-cell malignancies

An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities

Discrete layers of ordered fullerene C60 molecules in the cocrystal C60.cntdot.CH2I2.cntdot.C6H6: synthesis, crystal structure, and carbon-13 NMR properties

A total synthesis of (-)-discodermolide

ChemInform Abstract: Stereoselective Synthesis of anti-N-Protected 3-Amino-1,2-epoxides by Nucleophilic Addition to N-tert-Butanesulfinyl Imine of a Glyceraldehyde Synthon

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