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Vaccine-elicited Human T Cells Recognizing Conserved Protein Regions Inhibit HIV-1

Molecular therapy, 2014-02, Vol.22 (2), p.464-475

2014

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Safety and tolerability of conserved region vaccines vectored by plasmid DNA, simian adenovirus and modified vaccinia virus ankara administered to human immunodeficiency virus type 1-uninfected adults in a randomized, single-blind phase I trial

PloS one, 2014-07, Vol.9 (7), p.e101591-e101591

2014

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Complete protection of the BALB/c and C57BL/6J mice against Ebola and Marburg virus lethal challenges by pan-filovirus T-cell epigraph vaccine

PLoS pathogens, 2019-02, Vol.15 (2), p.e1007564

2019

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New vector and vaccine platforms: mRNA, DNA, viral vectors

Current opinion in HIV & AIDS, 2022-11, Vol.17 (6), p.338-344

Hanke, Tomáš

2022

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Defining the HLA class I‐associated viral antigen repertoire from HIV‐1‐infected human cells

European journal of immunology, 2016-01, Vol.46 (1), p.60-69

2016

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Aiming for protective T-cell responses: a focus on the first generation conserved-region HIVconsv vaccines in preventive and therapeutic clinical trials

Expert review of vaccines, 2019-10, Vol.18 (10), p.1029-1041

Hanke, Tomáš

2019

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Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial

The Lancet (British edition), 2020-03, Vol.395 (10227), p.888-898

2020

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Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (20), p.5682-5687

2016

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HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

PloS one, 2017-08, Vol.12 (8), p.e0181886-e0181886

2017

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Conserved immunogens in prime-boost strategies for the next-generation HIV-1 vaccines

Expert opinion on biological therapy, 2014-05, Vol.14 (5), p.601-616

Hanke, Tomáš

2014

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Superior Induction of T Cell Responses to Conserved HIV-1 Regions by Electroporated Alphavirus Replicon DNA Compared to That with Conventional Plasmid DNA Vaccine

Journal of Virology, 2012-04, Vol.86 (8), p.4082-4090

2012

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Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA–B27

Arthritis & rheumatology (Hoboken, N.J.), 2014-02, Vol.66 (2), p.284-294

2014

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Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges

PLoS pathogens, 2011-05, Vol.7 (5), p.e1002041-e1002041

2011

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A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques

Journal of translational medicine, 2015-02, Vol.13 (1), p.60-60, Article 60

2015

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Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells

Journal of virology, 2015-06, Vol.89 (11), p.5760-5771

2015

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A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection

Frontiers in immunology, 2019-01, Vol.9, p.3175-3175

2019

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Early Post-Vaccination Gene Signatures Correlate With the Magnitude and Function of Vaccine-Induced HIV Envelope-Specific Plasma Antibodies in Infant Rhesus Macaques

Frontiers in immunology, 2022-04, Vol.13, p.840976-840976

2022

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Growth patterns and their contributing factors among HIV‐exposed uninfected infants

Maternal and child nutrition, 2021-04, Vol.17 (2), p.e13110-n/a

2021

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Dendritic cells enter lymph vessels by hyaluronan-mediated docking to the endothelial receptor LYVE-1

Nature immunology, 2017-07, Vol.18 (7), p.762-770

2017

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Comparison of neutralizing antibody responses elicited from highly diverse polyvalent heterotrimeric HIV-1 gp140 cocktail immunogens versus a monovalent counterpart in rhesus macaques

PloS one, 2014-12, Vol.9 (12), p.e114709-e114709

2014

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Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses

PLoS pathogens, 2015-02, Vol.11 (2), p.e1004658-e1004658

2015

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Vaccine-elicited Human T Cells Recognizing Conserved Protein Regions Inhibit HIV-1

Safety and tolerability of conserved region vaccines vectored by plasmid DNA, simian adenovirus and modified vaccinia virus ankara administered to human immunodeficiency virus type 1-uninfected adults in a randomized, single-blind phase I trial

Complete protection of the BALB/c and C57BL/6J mice against Ebola and Marburg virus lethal challenges by pan-filovirus T-cell epigraph vaccine

New vector and vaccine platforms: mRNA, DNA, viral vectors

Defining the HLA class I‐associated viral antigen repertoire from HIV‐1‐infected human cells

Aiming for protective T-cell responses: a focus on the first generation conserved-region HIVconsv vaccines in preventive and therapeutic clinical trials

Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial

Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

Safety, immunogenicity and effect on viral rebound of HTI vaccines in early treated HIV-1 infection: a randomized, placebo-controlled phase 1 trial

Conserved immunogens in prime-boost strategies for the next-generation HIV-1 vaccines

Superior Induction of T Cell Responses to Conserved HIV-1 Regions by Electroporated Alphavirus Replicon DNA Compared to That with Conventional Plasmid DNA Vaccine

Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA–B27

Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges

A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques

Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells

HIVconsv Vaccines and Romidepsin in Early-Treated HIV-1-Infected Individuals: Safety, Immunogenicity and Effect on the Viral Reservoir (Study BCN02)

A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection

Early Post-Vaccination Gene Signatures Correlate With the Magnitude and Function of Vaccine-Induced HIV Envelope-Specific Plasma Antibodies in Infant Rhesus Macaques

Growth patterns and their contributing factors among HIV‐exposed uninfected infants

Dendritic cells enter lymph vessels by hyaluronan-mediated docking to the endothelial receptor LYVE-1

Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study)

Comparison of neutralizing antibody responses elicited from highly diverse polyvalent heterotrimeric HIV-1 gp140 cocktail immunogens versus a monovalent counterpart in rhesus macaques

Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses

Safety and immunogenicity of recombinant low-dosage HIV-1 A vaccine candidates vectored by plasmid pTHr DNA or modified vaccinia virus Ankara (MVA) in humans in East Africa

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