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Finding the will and the way of ERAD substrate retrotranslocation

Current opinion in cell biology, 2012-08, Vol.24 (4), p.460-466

2012

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The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins

Molecular cell, 2018-01, Vol.69 (2), p.306-320.e4

2018

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Proteostatic Tactics in the Strategy of Sterol Regulation

Annual review of cell and developmental biology, 2017-10, Vol.33 (1), p.467-489

2017

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Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (3), p.1106-1111

2010

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Direct and essential function for Hrd3 in ER-associated degradation

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (21), p.5934-5939

2016

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The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins

Molecular cell, 2015-07, Vol.59 (1), p.35-49

2015

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Misfolded Membrane Proteins Are Specifically Recognized by the Transmembrane Domain of the Hrd1p Ubiquitin Ligase

Molecular cell, 2009-04, Vol.34 (2), p.212-222

2009

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Protein Quality Control as a Strategy for Cellular Regulation: Lessons from Ubiquitin-Mediated Regulation of the Sterol Pathway

Chemical reviews, 2009-04, Vol.109 (4), p.1561-1574

2009

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Usa1p Is Required for Optimal Function and Regulation of the Hrd1p Endoplasmic Reticulum-associated Degradation Ubiquitin Ligase

The Journal of biological chemistry, 2010-02, Vol.285 (8), p.5146-5156

2010

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In Vitro Analysis of Hrd1p-mediated Retrotranslocation of Its Multispanning Membrane Substrate 3-Hydroxy-3-methylglutaryl (HMG)-CoA Reductase

The Journal of biological chemistry, 2009-05, Vol.284 (22), p.14710-14722

2009

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HRD Complex Self-Remodeling Enables a Novel Route of Membrane Protein Retrotranslocation

iScience, 2020-09, Vol.23 (9), p.101493, Article 101493

2020

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Cue1p Is an Activator of Ubc7p E2 Activity in Vitro and in Vivo

The Journal of biological chemistry, 2008-05, Vol.283 (19), p.12797-12810

2008

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Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast

The Journal of biological chemistry, 2009-12, Vol.284 (51), p.35368-35380

2009

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Cytosolic entry of Shiga-like toxin a chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p

PloS one, 2012-07, Vol.7 (7), p.e41119-e41119

2012

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The Sterol-sensing Domain (SSD) Directly Mediates Signal-regulated Endoplasmic Reticulum-associated Degradation (ERAD) of 3-Hydroxy-3-methylglutaryl (HMG)-CoA Reductase Isozyme Hmg2

The Journal of biological chemistry, 2011-07, Vol.286 (30), p.26298-26307

2011

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Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation

Nature cell biology, 2001-01, Vol.3 (1), p.24-29

2001

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“Mallostery”—ligand-dependent protein misfolding enables physiological regulation by ERAD

The Journal of biological chemistry, 2018-09, Vol.293 (38), p.14937-14950

2018

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The dynamic ER: experimental approaches and current questions

Current opinion in cell biology, 2005-08, Vol.17 (4), p.409-414

2005

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An autonomous, but INSIG-modulated, role for the sterol sensing domain in mallostery-regulated ERAD of yeast HMG-CoA reductase

The Journal of biological chemistry, 2021-01, Vol.296, p.100063-100063, Article 100063

2021

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PROTEOLYSIS AND STEROL REGULATION

Annual review of cell and developmental biology, 2002-01, Vol.18 (1), p.345-378

Hampton, Randolph Y

2002

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ER-associated degradation in protein quality control and cellular regulation

Current Opinion in Cell Biology, 2002-08, Vol.14 (4), p.476-482

Hampton, Randolph Y

2002

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Amplitude Control of Protein Kinase C by RINCK, a Novel E3 Ubiquitin Ligase

The Journal of biological chemistry, 2007-11, Vol.282 (46), p.33776-33787

2007

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Cod1p/Spf1p Is a P-Type ATPase Involved in ER Function and Ca2+Homeostasis

The Journal of cell biology, 2002-06, Vol.157 (6), p.1017-1028

2002

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New developments for protein quality control

Science (American Association for the Advancement of Science), 2017-08, Vol.357 (6350), p.450-451

2017

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Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control

Molecular biology of the cell, 2020-11, Vol.31 (24), p.2669-2686

2020

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Finding the will and the way of ERAD substrate retrotranslocation

The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins

Proteostatic Tactics in the Strategy of Sterol Regulation

Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

Direct and essential function for Hrd3 in ER-associated degradation

The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins

Misfolded Membrane Proteins Are Specifically Recognized by the Transmembrane Domain of the Hrd1p Ubiquitin Ligase

Protein Quality Control as a Strategy for Cellular Regulation: Lessons from Ubiquitin-Mediated Regulation of the Sterol Pathway

Usa1p Is Required for Optimal Function and Regulation of the Hrd1p Endoplasmic Reticulum-associated Degradation Ubiquitin Ligase

In Vitro Analysis of Hrd1p-mediated Retrotranslocation of Its Multispanning Membrane Substrate 3-Hydroxy-3-methylglutaryl (HMG)-CoA Reductase

HRD Complex Self-Remodeling Enables a Novel Route of Membrane Protein Retrotranslocation

Cue1p Is an Activator of Ubc7p E2 Activity in Vitro and in Vivo

Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast

Cytosolic entry of Shiga-like toxin a chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p

The Sterol-sensing Domain (SSD) Directly Mediates Signal-regulated Endoplasmic Reticulum-associated Degradation (ERAD) of 3-Hydroxy-3-methylglutaryl (HMG)-CoA Reductase Isozyme Hmg2

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation

“Mallostery”—ligand-dependent protein misfolding enables physiological regulation by ERAD

The dynamic ER: experimental approaches and current questions

An autonomous, but INSIG-modulated, role for the sterol sensing domain in mallostery-regulated ERAD of yeast HMG-CoA reductase

PROTEOLYSIS AND STEROL REGULATION

ER-associated degradation in protein quality control and cellular regulation

Amplitude Control of Protein Kinase C by RINCK, a Novel E3 Ubiquitin Ligase

Cod1p/Spf1p Is a P-Type ATPase Involved in ER Function and Ca2+Homeostasis

New developments for protein quality control

Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control

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