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Structure–Activity Relationship Studies on Isoindoline Inhibitors of Dipeptidyl Peptidases 8 and 9 (DPP8, DPP9): Is DPP8-Selectivity an Attainable Goal?

Journal of medicinal chemistry, 2011-08, Vol.54 (16), p.5737-5746

2011

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Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery

Current topics in medicinal chemistry, 2007-03, Vol.7 (6), p.621-635

2007

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Synthesis and Antiplasmodial Activity of Aminoalkylamino-Substituted Neocryptolepine Derivatives

Journal of medicinal chemistry, 2009-05, Vol.52 (9), p.2979-2988

2009

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Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.4159-4162

2008

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Evaluation of Nucleoside Hydrolase Inhibitors for Treatment of African Trypanosomiasis

Antimicrobial Agents and Chemotherapy, 2010-05, Vol.54 (5), p.1900-1908

2010

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In Vitro Antioxidant Profile of Phenolic Acid Derivatives

Free radical research, 2002-06, Vol.36 (6), p.711-716

2002

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Synthesis of 6-methyl-6H-indolo[3,2-c]isoquinoline and 6-methyl-6H-indolo[2,3-c]isoquinoline: two new unnatural isoquinoline isomers of the cryptolepine series

Tetrahedron, 2008-12, Vol.64 (51), p.11802-11809

2008

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Truncation of Macrophage-derived Chemokine by CD26/ Dipeptidyl-Peptidase IV beyond Its Predicted Cleavage Site Affects Chemotactic Activity and CC Chemokine Receptor 4 Interaction

The Journal of biological chemistry, 1999-02, Vol.274 (7), p.3988-3993

1999

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Fluoro-Olefins as Peptidomimetic Inhibitors of Dipeptidyl Peptidases

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.1768-1780

2005

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Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors

Biochimica et biophysica acta, 2009-06, Vol.1794 (6), p.953-960

2009

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Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA)

Bioorganic & medicinal chemistry, 2012-02, Vol.20 (4), p.1557-1568

2012

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Small, Potent, and Selective Diaryl Phosphonate Inhibitors for Urokinase-Type Plasminogen Activator with In Vivo Antimetastatic Properties

Journal of medicinal chemistry, 2007-12, Vol.50 (26), p.6638-6646

2007

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Schistosomicidal and molluscicidal activities of aminoalkylamino substituted neo- and norneocryptolepine derivatives

Pharmaceutical biology, 2012-02, Vol.50 (2), p.134-140

2012

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Irreversible Inhibition of Dipeptidyl Peptidase 8 by Dipeptide-Derived Diaryl Phosphonates

Journal of medicinal chemistry, 2007-11, Vol.50 (23), p.5568-5570

2007

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Inhibitors of proline-specific dipeptidyl peptidases: DPP IV inhibitors as a novel approach for the treatment of Type 2 diabetes

Expert opinion on therapeutic patents, 2005-10, Vol.15 (10), p.1387-1407

2005

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N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase

Bioorganic & medicinal chemistry, 2008-07, Vol.16 (14), p.6752-6763

2008

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α-Ketoheterocycles as Inhibitors of Leishmania mexicana Cysteine Protease CPB

ChemMedChem, 2010-10, Vol.5 (10), p.1734-1748

2010

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Synthesis of Isocryptolepine via a Pd-Catalyzed ‘Amination-Arylation’ Approach

Synlett, 2003-04, Vol.2003 (5)

2003

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Synthesis and evaluation of caffeic acid amides as antioxidants

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (2), p.215-217

2001

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Design and evaluation of Trypanosoma brucei metacaspase inhibitors

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (6), p.2001-2006

2010

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Diphenyl Phosphonate Inhibitors for the Urokinase-Type Plasminogen Activator: Optimization of the P4 Position

Journal of medicinal chemistry, 2006-09, Vol.49 (19), p.5785-5793

2006

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Dipeptidyl α-fluorovinyl Michael acceptors: Synthesis and activity against cysteine proteases

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6563-6566

2007

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Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: Identification of dipeptide derived leads

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.4154-4158

2008

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Characterization of the peptide substrate specificity of glutathionylspermidine synthetase from Crithidia fasciculata

Molecular and biochemical parasitology, 1997, Vol.84 (1), p.25-32

1997

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Design, Synthesis, and SAR of Potent and Selective Dipeptide-Derived Inhibitors for Dipeptidyl Peptidases

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.5005-5014

2003

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Structure–Activity Relationship Studies on Isoindoline Inhibitors of Dipeptidyl Peptidases 8 and 9 (DPP8, DPP9): Is DPP8-Selectivity an Attainable Goal?

Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery

Synthesis and Antiplasmodial Activity of Aminoalkylamino-Substituted Neocryptolepine Derivatives

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors

Evaluation of Nucleoside Hydrolase Inhibitors for Treatment of African Trypanosomiasis

In Vitro Antioxidant Profile of Phenolic Acid Derivatives

Synthesis of 6-methyl-6H-indolo[3,2-c]isoquinoline and 6-methyl-6H-indolo[2,3-c]isoquinoline: two new unnatural isoquinoline isomers of the cryptolepine series

Truncation of Macrophage-derived Chemokine by CD26/ Dipeptidyl-Peptidase IV beyond Its Predicted Cleavage Site Affects Chemotactic Activity and CC Chemokine Receptor 4 Interaction

Fluoro-Olefins as Peptidomimetic Inhibitors of Dipeptidyl Peptidases

Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors

Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA)

Small, Potent, and Selective Diaryl Phosphonate Inhibitors for Urokinase-Type Plasminogen Activator with In Vivo Antimetastatic Properties

Schistosomicidal and molluscicidal activities of aminoalkylamino substituted neo- and norneocryptolepine derivatives

Irreversible Inhibition of Dipeptidyl Peptidase 8 by Dipeptide-Derived Diaryl Phosphonates

Inhibitors of proline-specific dipeptidyl peptidases: DPP IV inhibitors as a novel approach for the treatment of Type 2 diabetes

N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase

α-Ketoheterocycles as Inhibitors of Leishmania mexicana Cysteine Protease CPB

Synthesis of Isocryptolepine via a Pd-Catalyzed ‘Amination-Arylation’ Approach

Synthesis and evaluation of caffeic acid amides as antioxidants

Design and evaluation of Trypanosoma brucei metacaspase inhibitors

Diphenyl Phosphonate Inhibitors for the Urokinase-Type Plasminogen Activator: Optimization of the P4 Position

Dipeptidyl α-fluorovinyl Michael acceptors: Synthesis and activity against cysteine proteases

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: Identification of dipeptide derived leads

Characterization of the peptide substrate specificity of glutathionylspermidine synthetase from Crithidia fasciculata

Design, Synthesis, and SAR of Potent and Selective Dipeptide-Derived Inhibitors for Dipeptidyl Peptidases

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