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PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells

Nature communications, 2021-11, Vol.12 (1), p.6505-6505, Article 6505

2021

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The Role of β-Arrestin Proteins in Organization of Signaling and Regulation of the AT1 Angiotensin Receptor

Frontiers in endocrinology (Lausanne), 2019-08, Vol.10, p.519-519

2019

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Effect of hormone-induced plasma membrane phosphatidylinositol 4,5-bisphosphate depletion on receptor endocytosis suggests the importance of local regulation in phosphoinositide signaling

Scientific reports, 2024-01, Vol.14 (1), p.291-291, Article 291

2024

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Heterologous phosphorylation–induced formation of a stability lock permits regulation of inactive receptors by β-arrestins

The Journal of biological chemistry, 2018-01, Vol.293 (3), p.876-892

2018

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Personalized medicine can pave the way for the safe use of CB1 receptor antagonists

Trends in pharmacological sciences (Regular ed.), 2011-05, Vol.32 (5), p.270-280

2011

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Mutation in the V2 vasopressin receptor gene, AVPR2, causes nephrogenic syndrome of inappropriate diuresis

Kidney international, 2015-11, Vol.88 (5), p.1070-1078

2015

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ArreSTick motif controls β-arrestin-binding stability and extends phosphorylation-dependent β-arrestin interactions to non-receptor proteins

Cell reports (Cambridge), 2024-05, Vol.43 (5), p.114241, Article 114241

2024

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Improved methodical approach for quantitative BRET analysis of G Protein Coupled Receptor dimerization

PloS one, 2014-10, Vol.9 (10), p.e109503-e109503

2014

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Proteomic Changes of Osteoclast Differentiation in Rheumatoid and Psoriatic Arthritis Reveal Functional Differences

Frontiers in immunology, 2022-07, Vol.13, p.892970-892970

2022

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Role of CB1 Cannabinoid Receptors in Vascular Responses and Vascular Remodeling of the Aorta in Female Mice

International journal of molecular sciences, 2023-11, Vol.24 (22), p.16429

2023

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Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins

The Journal of biological chemistry, 2017-11, Vol.292 (46), p.18862-18877

2017

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An Unexpected Enzyme in Vascular Smooth Muscle Cells: Angiotensin II Upregulates Cholesterol-25-Hydroxylase Gene Expression

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3968

2023

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Crowdsourced mapping of unexplored target space of kinase inhibitors

Nature communications, 2021-06, Vol.12 (1), p.3307-18, Article 3307

2021

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Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity

PLoS computational biology, 2022-04, Vol.18 (4), p.e1010021-e1010021

2022

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A general method for quantifying ligand binding to unmodified receptors using Gaussia luciferase

The Journal of biological chemistry, 2021-01, Vol.296, p.100366, Article 100366

2021

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Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones

Frontiers in pharmacology, 2022-01, Vol.13 (79), p.811836-811836

2022

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Disruption of the NOX5 Gene Aggravates Atherosclerosis in Rabbits

Circulation research, 2021-04, Vol.128 (9), p.1320-1322

2021

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Impact of Medium-Sized Extracellular Vesicles on the Transduction Efficiency of Adeno-Associated Viruses in Neuronal and Primary Astrocyte Cell Cultures

International journal of molecular sciences, 2021-04, Vol.22 (8), p.4221

2021

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Biased Coupling to β-Arrestin of Two Common Variants of the CB2 Cannabinoid Receptor

Frontiers in endocrinology (Lausanne), 2021-08, Vol.12, p.714561-714561

2021

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Role of the Endocannabinoid System in Metabolic Control Processes and in the Pathogenesis of Metabolic Syndrome: An Update

Biomedicines, 2023-01, Vol.11 (2), p.306

2023

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Investigation of the fate of type I angiotensin receptor after biased activation

Molecular pharmacology, 2015-06, Vol.87 (6), p.972-981

2015

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Optimization of the Heterologous Expression of the Cannabinoid Type-1 (CB 1 ) Receptor

Frontiers in endocrinology (Lausanne), 2021-10, Vol.12, p.740913-740913

2021

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Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors

PloS one, 2015-05, Vol.10 (5), p.e0125601-e0125601

2015

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BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation

Biochimica et biophysica acta, 2016-03, Vol.1861 (3), p.177-187

2016

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Signal transduction of the CB1 cannabinoid receptor

Journal of molecular endocrinology, 2010-02, Vol.44 (2), p.75-85

2010

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PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells

The Role of β-Arrestin Proteins in Organization of Signaling and Regulation of the AT1 Angiotensin Receptor

Effect of hormone-induced plasma membrane phosphatidylinositol 4,5-bisphosphate depletion on receptor endocytosis suggests the importance of local regulation in phosphoinositide signaling

Heterologous phosphorylation–induced formation of a stability lock permits regulation of inactive receptors by β-arrestins

Personalized medicine can pave the way for the safe use of CB1 receptor antagonists

Mutation in the V2 vasopressin receptor gene, AVPR2, causes nephrogenic syndrome of inappropriate diuresis

ArreSTick motif controls β-arrestin-binding stability and extends phosphorylation-dependent β-arrestin interactions to non-receptor proteins

Improved methodical approach for quantitative BRET analysis of G Protein Coupled Receptor dimerization

Proteomic Changes of Osteoclast Differentiation in Rheumatoid and Psoriatic Arthritis Reveal Functional Differences

Role of CB1 Cannabinoid Receptors in Vascular Responses and Vascular Remodeling of the Aorta in Female Mice

Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins

An Unexpected Enzyme in Vascular Smooth Muscle Cells: Angiotensin II Upregulates Cholesterol-25-Hydroxylase Gene Expression

Crowdsourced mapping of unexplored target space of kinase inhibitors

Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity

A general method for quantifying ligand binding to unmodified receptors using Gaussia luciferase

Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones

Disruption of the NOX5 Gene Aggravates Atherosclerosis in Rabbits

Impact of Medium-Sized Extracellular Vesicles on the Transduction Efficiency of Adeno-Associated Viruses in Neuronal and Primary Astrocyte Cell Cultures

Biased Coupling to β-Arrestin of Two Common Variants of the CB2 Cannabinoid Receptor

Role of the Endocannabinoid System in Metabolic Control Processes and in the Pathogenesis of Metabolic Syndrome: An Update

Investigation of the fate of type I angiotensin receptor after biased activation

Optimization of the Heterologous Expression of the Cannabinoid Type-1 (CB 1 ) Receptor

Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors

BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation

Signal transduction of the CB1 cannabinoid receptor

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