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Systemic Protein Therapy for Recessive Dystrophic Epidermolysis Bullosa: How Far Are We from Clinical Translation?

Journal of investigative dermatology, 2013-07, Vol.133 (7), p.1719-1721

Hovnanian, Alain

2013

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Netherton syndrome: defective kallikrein inhibition in the skin leads to skin inflammation and allergy

Biological chemistry, 2014-09, Vol.395 (9), p.945-958

2014

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TSLP-activated dendritic cells induce human T follicular helper cell differentiation through OX40-ligand

The Journal of experimental medicine, 2017-05, Vol.214 (5), p.1529-1546

2017

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Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome

The Journal of experimental medicine, 2009-05, Vol.206 (5), p.1135-1147

2009

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Meganuclease-Mediated COL7A1 Gene Correction for Recessive Dystrophic Epidermolysis Bullosa

Journal of investigative dermatology, 2016-04, Vol.136 (4), p.872-875

2016

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Netherton syndrome: skin inflammation and allergy by loss of protease inhibition

Cell and tissue research, 2013-02, Vol.351 (2), p.289-300

Hovnanian, Alain

2013

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KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome

PLoS genetics, 2015-09, Vol.11 (9), p.e1005389-e1005389

2015

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Erythrokeratodermia Variabilis et Progressiva Allelic to Oculo-Dento-Digital Dysplasia

Journal of investigative dermatology, 2015-06, Vol.135 (6), p.1475-1478

2015

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Ex Vivo COL7A1 Correction for Recessive Dystrophic Epidermolysis Bullosa Using CRISPR/Cas9 and Homology-Directed Repair

Molecular therapy. Nucleic acids, 2018-09, Vol.12, p.554-567

2018

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Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome

The Journal of experimental medicine, 2014-03, Vol.211 (3), p.499-513

2014

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Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

Nature medicine, 2007-08, Vol.13 (8), p.975-980

2007

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Efficacy of Dupilumab for Controlling Severe Atopic Dermatitis in a Patient with Hyper-IgE Syndrome

Journal of clinical immunology, 2020-02, Vol.40 (2), p.418-420

2020

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Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome

Cell reports (Cambridge), 2020-03, Vol.30 (9), p.2923-2933.e7

2020

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Bacterial pathogens associated with hidradenitis suppurativa, France

Emerging infectious diseases, 2014-12, Vol.20 (12), p.1990-1998

2014

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Gene-Corrected Fibroblast Therapy for Recessive Dystrophic Epidermolysis Bullosa using a Self-Inactivating COL7A1 Retroviral Vector

Journal of investigative dermatology, 2016-07, Vol.136 (7), p.1346-1354

2016

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A European study of HLA-B in Stevens–Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs

Pharmacogenetics and genomics, 2008-02, Vol.18 (2), p.99-107

2008

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The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB

Journal of the American Academy of Dermatology, 2008-06, Vol.58 (6), p.931-950

2008

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Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe

Orphanet journal of rare diseases, 2011-07, Vol.6 (1), p.52-52

2011

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Generation and characterization of induced pluripotent stem cell lines from two patients with recessive dystrophic epidermolysis Bullosa

Stem cell research, 2023-06, Vol.69, p.103104-103104, Article 103104

2023

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Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities[S]

Journal of lipid research, 2020-06, Vol.61 (6), p.859-869

2020

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Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients

Journal of investigative dermatology, 2014-05, Vol.134 (5), p.1238-1245

2014

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Infliximab Infusions for Netherton Syndrome: Sustained Clinical Improvement Correlates with a Reduction of Thymic Stromal Lymphopoietin Levels in the Skin

Journal of investigative dermatology, 2011-09, Vol.131 (9), p.1947-1950

2011

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LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction

Molecular biology of the cell, 2007-09, Vol.18 (9), p.3607-3619

2007

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SPCA1 governs the stability of TMEM165 in Hailey-Hailey disease

Biochimie, 2020-07, Vol.174, p.159-170

2020

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Systemic Protein Therapy for Recessive Dystrophic Epidermolysis Bullosa: How Far Are We from Clinical Translation?

Netherton syndrome: defective kallikrein inhibition in the skin leads to skin inflammation and allergy

TSLP-activated dendritic cells induce human T follicular helper cell differentiation through OX40-ligand

Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome

Meganuclease-Mediated COL7A1 Gene Correction for Recessive Dystrophic Epidermolysis Bullosa

Netherton syndrome: skin inflammation and allergy by loss of protease inhibition

Inherited epidermolysis bullosa: Updated recommendations on diagnosis and classification

KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome

Erythrokeratodermia Variabilis et Progressiva Allelic to Oculo-Dento-Digital Dysplasia

Ex Vivo COL7A1 Correction for Recessive Dystrophic Epidermolysis Bullosa Using CRISPR/Cas9 and Homology-Directed Repair

Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome

Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

Efficacy of Dupilumab for Controlling Severe Atopic Dermatitis in a Patient with Hyper-IgE Syndrome

Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome

Bacterial pathogens associated with hidradenitis suppurativa, France

Gene-Corrected Fibroblast Therapy for Recessive Dystrophic Epidermolysis Bullosa using a Self-Inactivating COL7A1 Retroviral Vector

A European study of HLA-B in Stevens–Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs

The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB

Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe

Generation and characterization of induced pluripotent stem cell lines from two patients with recessive dystrophic epidermolysis Bullosa

Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities[S]

Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients

Infliximab Infusions for Netherton Syndrome: Sustained Clinical Improvement Correlates with a Reduction of Thymic Stromal Lymphopoietin Levels in the Skin

LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction

SPCA1 governs the stability of TMEM165 in Hailey-Hailey disease

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