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Analysis of the gut microbiota in the old order Amish and its relation to the metabolic syndrome

PloS one, 2012-08, Vol.7 (8), p.e43052-e43052

2012

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Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy

JAMA : the journal of the American Medical Association, 2009-08, Vol.302 (8), p.849

2009

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Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications

PLoS medicine, 2006-06, Vol.3 (6), p.e287

2006

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Purine Pathway Implicated in Mechanism of Resistance to Aspirin Therapy: Pharmacometabolomics-Informed Pharmacogenomics

Clinical pharmacology and therapeutics, 2013-10, Vol.94 (4), p.525-532

2013

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Implementation of pharmacogenetics: The University of Maryland personalized anti-platelet pharmacogenetics program

American journal of medical genetics. Part C, Seminars in medical genetics, 2014-03, Vol.166C (1), p.76-84

2014

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The CYP2C1917 variant is not independently associated with clopidogrel response

Journal of thrombosis and haemostasis, 2013-09, Vol.11 (9), p.1640-1646

2013

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Pharmacogenetics and Clopidogrel Response in Patients Undergoing Percutaneous Coronary Interventions

Clinical pharmacology and therapeutics, 2011-03, Vol.89 (3), p.455-459

2011

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Paraoxonase 1 ( ) Gene Variants Are Not Associated With Clopidogrel Response

Clinical pharmacology and therapeutics, 2011-10, Vol.90 (4), p.568-574

2011

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Effects of APOC3 Heterozygous Deficiency on Plasma Lipid and Lipoprotein Metabolism

Arteriosclerosis, thrombosis, and vascular biology, 2019-01, Vol.39 (1), p.63-72

2019

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Identifying clinically relevant sources of variability: The clopidogrel challenge

Clinical pharmacology and therapeutics, 2017-02, Vol.101 (2), p.264-273

2017

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The Pharmacogenomics of Anti-Platelet Intervention (PAPI) Study: Variation in Platelet Response to Clopidogrel and Aspirin

Current vascular pharmacology, 2016-01, Vol.14 (1), p.116-124

2016

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A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing

The New England journal of medicine, 2013-12, Vol.369 (24), p.2283-2293

2013

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Cholesterol predicts stroke mortality in the Women's Pooling project

Stroke (1970), 2002-07, Vol.33 (7), p.1863-1868

2002

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The genetic response to short-term interventions affecting cardiovascular function: Rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study

The American heart journal, 2008-05, Vol.155 (5), p.823-828

2008

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Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection

Science (American Association for the Advancement of Science), 2008-12, Vol.322 (5908), p.1702-1705

2008

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Null Mutation in Hormone-Sensitive Lipase Gene and Risk of Type 2 Diabetes

The New England journal of medicine, 2014-06, Vol.370 (24), p.2307-2315

2014

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Prospective Evaluation of Genetic Variation in Platelet Endothelial Aggregation Receptor 1 Reveals Aspirin‐Dependent Effects on Platelet Aggregation Pathways

Clinical and translational science, 2017-03, Vol.10 (2), p.102-109

2017

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The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

Pharmacogenetics and genomics, 2013-01, Vol.23 (1), p.1-8

2013

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Pharmacometabolomics Reveals That Serotonin Is Implicated in Aspirin Response Variability

CPT: pharmacometrics and systems pharmacology, 2014-07, Vol.3 (7), p.1-9

2014

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Pharmacogenetic Associations of β1-Adrenergic Receptor Polymorphisms With Cardiovascular Outcomes in the SPS3 Trial (Secondary Prevention of Small Subcortical Strokes)

Stroke (1970), 2017-05, Vol.48 (5), p.1337-1343

2017

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Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points—Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC)

The American heart journal, 2018-04, Vol.198, p.152-159

2018

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A systematic analysis and comparison of warfarin initiation strategies

Pharmacogenetics and genomics, 2016-10, Vol.26 (10), p.445-452

2016

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Development of a physiology-directed population pharmacokinetic and pharmacodynamic model for characterizing the impact of genetic and demographic factors on clopidogrel response in healthy adults

European journal of pharmaceutical sciences, 2016-01, Vol.82, p.64-78

2016

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Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes

Circulation. Cardiovascular genetics, 2013-04, Vol.6 (2), p.184-192

2013

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Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response

Pharmacogenetics and genomics, 2017-04, Vol.27 (4), p.159-163

2017

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Analysis of the gut microbiota in the old order Amish and its relation to the metabolic syndrome

Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy

Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications

Purine Pathway Implicated in Mechanism of Resistance to Aspirin Therapy: Pharmacometabolomics-Informed Pharmacogenomics

Implementation of pharmacogenetics: The University of Maryland personalized anti-platelet pharmacogenetics program

The CYP2C1917 variant is not independently associated with clopidogrel response

Pharmacogenetics and Clopidogrel Response in Patients Undergoing Percutaneous Coronary Interventions

Paraoxonase 1 ( ) Gene Variants Are Not Associated With Clopidogrel Response

Effects of APOC3 Heterozygous Deficiency on Plasma Lipid and Lipoprotein Metabolism

Identifying clinically relevant sources of variability: The clopidogrel challenge

The Pharmacogenomics of Anti-Platelet Intervention (PAPI) Study: Variation in Platelet Response to Clopidogrel and Aspirin

A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing

Cholesterol predicts stroke mortality in the Women's Pooling project

The genetic response to short-term interventions affecting cardiovascular function: Rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study

Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection

Null Mutation in Hormone-Sensitive Lipase Gene and Risk of Type 2 Diabetes

Prospective Evaluation of Genetic Variation in Platelet Endothelial Aggregation Receptor 1 Reveals Aspirin‐Dependent Effects on Platelet Aggregation Pathways

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

Pharmacometabolomics Reveals That Serotonin Is Implicated in Aspirin Response Variability

Pharmacogenetic Associations of β1-Adrenergic Receptor Polymorphisms With Cardiovascular Outcomes in the SPS3 Trial (Secondary Prevention of Small Subcortical Strokes)

Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points—Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC)

A systematic analysis and comparison of warfarin initiation strategies

Development of a physiology-directed population pharmacokinetic and pharmacodynamic model for characterizing the impact of genetic and demographic factors on clopidogrel response in healthy adults

Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes

Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response

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