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Predicting drug‐induced QT prolongation and torsades de pointes

The Journal of physiology, 2016-05, Vol.594 (9), p.2459-2468

Roden, Dan M.

2016

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A current understanding of drug-induced QT prolongation and its implications for anticancer therapy

Cardiovascular research, 2019-04, Vol.115 (5), p.895-903

Roden, Dan M

2019

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Considerations for Drug Interactions on QTc in Exploratory COVID-19 Treatment

Circulation (New York, N.Y.), 2020-06, Vol.141 (24), p.e906-e907

2020

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Drug-Induced Prolongation of the QT Interval

The New England journal of medicine, 2004-03, Vol.350 (10), p.1013-1022

2004

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Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record

PloS one, 2017-07, Vol.12 (7), p.e0175508-e0175508

2017

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Fulminant Myocarditis with Combination Immune Checkpoint Blockade

The New England journal of medicine, 2016-11, Vol.375 (18), p.1749-1755

2016

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The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies

BMC genomics, 2011-01, Vol.4 (1), p.13-13, Article 13

2011

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The 3D mutational constraint on amino acid sites in the human proteome

Nature communications, 2022-06, Vol.13 (1), p.3273-3273, Article 3273

2022

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Classification and Reporting of Potentially Proarrhythmic Common Genetic Variation in Long QT Syndrome Genetic Testing

Circulation (New York, N.Y.), 2018-02, Vol.137 (6), p.619-630

2018

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PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations

Bioinformatics, 2010-05, Vol.26 (9), p.1205-1210

2010

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Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

JAMA : the journal of the American Medical Association, 2018-12, Vol.320 (22), p.2354

2018

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Close bidirectional relationship between chronic kidney disease and atrial fibrillation: The Niigata preventive medicine study

The American heart journal, 2009-10, Vol.158 (4), p.629-636

2009

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High-Throughput Reclassification of SCN5A Variants

American journal of human genetics, 2020-07, Vol.107 (1), p.111-123

2020

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A Common Genetic Variant Risk Score is Associated with Drug-Induced QT Prolongation and Torsade de Pointes Risk: A Pilot Study

Circulation (New York, N.Y.), 2017-04, Vol.135 (14), p.1300-1310

2017

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PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability

Journal of the American Medical Informatics Association : JAMIA, 2016-11, Vol.23 (6), p.1046-1052

2016

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The phenotypic legacy of admixture between modern humans and Neandertals

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6274), p.737-741

2016

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Genetic mechanisms of atrial fibrillation: impact on response to treatment

Nature reviews cardiology, 2013-06, Vol.10 (6), p.317

2013

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Comparison of HLA allelic imputation programs

PloS one, 2017-02, Vol.12 (2), p.e0172444-e0172444

2017

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A Bayesian method to estimate variant-induced disease penetrance

PLoS genetics, 2020-06, Vol.16 (6), p.e1008862-e1008862

2020

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Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery

Circulation (New York, N.Y.), 2019-01, Vol.139 (4), p.489-501

2019

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Cardiovascular pharmacogenomics: current status and future directions

Journal of human genetics, 2016-01, Vol.61 (1), p.79-85

Roden, Dan M

2016

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Drugs and Brugada syndrome patients: Review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org)

Heart rhythm, 2009-09, Vol.6 (9), p.1335-1341

2009

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Benefit of Preemptive Pharmacogenetic Information on Clinical Outcome

Clinical pharmacology and therapeutics, 2018-05, Vol.103 (5), p.787-794

2018

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The Lambeth Conventions (II): Guidelines for the study of animal and human ventricular and supraventricular arrhythmias

Pharmacology & therapeutics (Oxford), 2013-08, Vol.139 (2), p.213-248

2013

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Predicting drug‐induced QT prolongation and torsades de pointes

A current understanding of drug-induced QT prolongation and its implications for anticancer therapy

Considerations for Drug Interactions on QTc in Exploratory COVID-19 Treatment

Drug-Induced Prolongation of the QT Interval

Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record

Fulminant Myocarditis with Combination Immune Checkpoint Blockade

The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies

The 3D mutational constraint on amino acid sites in the human proteome

Classification and Reporting of Potentially Proarrhythmic Common Genetic Variation in Long QT Syndrome Genetic Testing

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations

Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

Close bidirectional relationship between chronic kidney disease and atrial fibrillation: The Niigata preventive medicine study

High-Throughput Reclassification of SCN5A Variants

A Common Genetic Variant Risk Score is Associated with Drug-Induced QT Prolongation and Torsade de Pointes Risk: A Pilot Study

PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability

The phenotypic legacy of admixture between modern humans and Neandertals

Genetic mechanisms of atrial fibrillation: impact on response to treatment

Comparison of HLA allelic imputation programs

A Bayesian method to estimate variant-induced disease penetrance

Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery

Cardiovascular pharmacogenomics: current status and future directions

Drugs and Brugada syndrome patients: Review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org)

Benefit of Preemptive Pharmacogenetic Information on Clinical Outcome

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

The Lambeth Conventions (II): Guidelines for the study of animal and human ventricular and supraventricular arrhythmias

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