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Use of broadly neutralizing antibodies for HIV‐1 prevention

Immunological reviews, 2017-01, Vol.275 (1), p.296-312

2017

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Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers

PLoS pathogens, 2009-05, Vol.5 (5), p.e1000433-e1000433

2009

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Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

Nature, 2008-07, Vol.454 (7201), p.177-182

2008

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Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques

Nature medicine, 2009-08, Vol.15 (8), p.951-954

2009

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Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis

Nature communications, 2022-02, Vol.13 (1), p.662-662, Article 662

2022

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Passive and active antibody studies in primates to inform HIV vaccines

Expert review of vaccines, 2018-02, Vol.17 (2), p.127-144

2018

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Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (27), p.11181-11186

2011

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Structural definition of a conserved neutralization epitope on HIV-1 gp120

Nature, 2007-02, Vol.445 (7129), p.732-737

2007

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Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L

Journal of Virology, 2010-02, Vol.84 (3), p.1302-1313

2010

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Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

Nature communications, 2020-01, Vol.11 (1), p.70-70, Article 70

2020

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

Science (American Association for the Advancement of Science), 2009-11, Vol.326 (5956), p.1123-1127

2009

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Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir

Nature communications, 2023-10, Vol.14 (1), p.6710-6710, Article 6710

2023

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Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice

PLoS pathogens, 2022-01, Vol.18 (1), p.e1010183-e1010183

2022

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Sex- and species-associated differences in complement-mediated immunity in humans and rhesus macaques

mBio, 2024-02, Vol.15 (3), p.e0028224-e0028224

2024

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Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines

Nature communications, 2022-02, Vol.13 (1), p.903-903, Article 903

2022

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Advancing HIV Broadly Neutralizing Antibodies: From Discovery to the Clinic

Frontiers in public health, 2021-05, Vol.9

2021

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Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity

mBio, 2021-10, Vol.12 (5), p.e0174321-e0174321

2021

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Polyfunctional Tier 2-Neutralizing Antibodies Cloned following HIV-1 Env Macaque Immunization Mirror Native Antibodies in a Human Donor

The Journal of immunology (1950), 2021-03, Vol.206 (5), p.999-1012

2021

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Vaccination with immune complexes modulates the elicitation of functional antibodies against HIV-1

Frontiers in immunology, 2023-10, Vol.14, p.1271686-1271686

2023

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Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates

mBio, 2023-04, Vol.14 (2), p.e0034123-e0034123

2023

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Corrigendum: Vaccination with immune complexes modulates the elicitation of functional antibodies against HIV-1

Frontiers in immunology, 2023-11, Vol.14, p.1329069-1329069

2023

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Induction of neutralizing antibodies in rhesus macaques using V3 mimotope peptides

Vaccine, 2016-05, Vol.34 (24), p.2713-2721

2016

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A Panel of IgG1 b12 Variants with Selectively Diminished or Enhanced Affinity for Fcγ Receptors To Define the Role of Effector Functions in Protection against HIV

Journal of Virology, 2011-10, Vol.85 (20), p.10572-10581

2011

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Simplifying the synthesis of SIgA: Combination of dIgA and rhSC using affinity chromatography

Methods (San Diego, Calif.), 2014-01, Vol.65 (1), p.127-132

2014

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Use of broadly neutralizing antibodies for HIV‐1 prevention

Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques

Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis

Passive and active antibody studies in primates to inform HIV vaccines

Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody

Structural definition of a conserved neutralization epitope on HIV-1 gp120

Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L

Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir

Non-neutralizing antibodies targeting the immunogenic regions of HIV-1 envelope reduce mucosal infection and virus burden in humanized mice

Sex- and species-associated differences in complement-mediated immunity in humans and rhesus macaques

Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines

Advancing HIV Broadly Neutralizing Antibodies: From Discovery to the Clinic

Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity

Polyfunctional Tier 2-Neutralizing Antibodies Cloned following HIV-1 Env Macaque Immunization Mirror Native Antibodies in a Human Donor

Vaccination with immune complexes modulates the elicitation of functional antibodies against HIV-1

A Nonfucosylated Variant of the anti-HIV-1 Monoclonal Antibody b12 Has Enhanced FcγRIIIa-Mediated Antiviral Activity In Vitro but Does Not Improve Protection against Mucosal SHIV Challenge in Macaques

Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates

Corrigendum: Vaccination with immune complexes modulates the elicitation of functional antibodies against HIV-1

Induction of neutralizing antibodies in rhesus macaques using V3 mimotope peptides

A Panel of IgG1 b12 Variants with Selectively Diminished or Enhanced Affinity for Fcγ Receptors To Define the Role of Effector Functions in Protection against HIV

Simplifying the synthesis of SIgA: Combination of dIgA and rhSC using affinity chromatography

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