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Future of Personalized Medicine in Oncology: A Systems Biology Approach

Journal of clinical oncology, 2010-06, Vol.28 (16), p.2777-2783

2010

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Non-parametric quantification of protein lysate arrays

Bioinformatics, 2007-08, Vol.23 (15), p.1986-1994

2007

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Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy

The Journal of clinical investigation, 2011-04, Vol.121 (4), p.1231-1241

2011

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Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer

Journal of clinical oncology, 2010-08, Vol.28 (22), p.3570-3576

2010

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Ovarian cancer

The Lancet (British edition), 2009-10, Vol.374 (9698), p.1371-1382

2009

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Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

Carcinogenesis (New York), 2013-10, Vol.34 (10), p.2300-2308

2013

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Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery

Nature reviews. Drug discovery, 2005-12, Vol.4 (12), p.988-1004

2005

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The biology of ovarian cancer: new opportunities for translation

Nature reviews. Cancer, 2009-06, Vol.9 (6), p.415-428

2009

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Chromosomal copy number and mutational status are required to authenticate ovarian cancer cell lines as appropriate cell models

Molecular biology reports, 2024-12, Vol.51 (1), p.784, Article 784

2024

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Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer

The Journal of clinical investigation, 2010-07, Vol.120 (7), p.2406-2413

2010

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A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer

Cancer cell, 2007-10, Vol.12 (4), p.395-402

2007

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Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

Cancer research (Chicago, Ill.), 2009-05, Vol.69 (10), p.4116-4124

2009

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Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

Breast cancer research : BCR, 2010-06, Vol.12 (3), p.R40-R40, Article R40

2010

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An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

Cancer research (Chicago, Ill.), 2008-08, Vol.68 (15), p.6084-6091

2008

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Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing

Modern pathology, 2012-05, Vol.25 (5), p.699-708

2012

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One year of procarbazine lomustine and vincristine is poorly tolerated in low grade glioma: a real world experience in a national neuro-oncology centre

BMC cancer, 2021-02, Vol.21 (1), p.140-140, Article 140

2021

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Use of exhaled breath condensate (EBC) in the diagnosis of SARS-COV-2 (COVID-19)

Thorax, 2021-01, Vol.76 (1), p.86

2021

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High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability

Cancer discovery, 2011-07, Vol.1 (2), p.170-185

2011

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Triple Receptor–Negative Breast Cancer: The Effect of Race on Response to Primary Systemic Treatment and Survival Outcomes

Journal of clinical oncology, 2009-01, Vol.27 (2), p.220-226

2009

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Preclinical evaluation of the CDK4/6 inhibitor palbociclib in combination with a PI3K or MEK inhibitor in colorectal cancer

Cancer biology & therapy, 2023-12, Vol.24 (1), p.2223388-2223388

2023

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PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor—positive breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (22), p.10208-10213

2010

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Incidence and Outcome of BRCA Mutations in Unselected Patients with Triple Receptor-Negative Breast Cancer

Clinical cancer research, 2011-03, Vol.17 (5), p.1082-1089

2011

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Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

Journal of clinical oncology, 2008-03, Vol.26 (8), p.1275-1281

2008

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Mammary angiosarcomas: imaging findings in 24 patients

Radiology, 2007-03, Vol.242 (3), p.725

2007

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Future of Personalized Medicine in Oncology: A Systems Biology Approach

Non-parametric quantification of protein lysate arrays

Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy

Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer

Ovarian cancer

Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery

The biology of ovarian cancer: new opportunities for translation

Chromosomal copy number and mutational status are required to authenticate ovarian cancer cell lines as appropriate cell models

Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer

A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer

Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer

Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing

One year of procarbazine lomustine and vincristine is poorly tolerated in low grade glioma: a real world experience in a national neuro-oncology centre

Use of exhaled breath condensate (EBC) in the diagnosis of SARS-COV-2 (COVID-19)

High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability

Triple Receptor–Negative Breast Cancer: The Effect of Race on Response to Primary Systemic Treatment and Survival Outcomes

Preclinical evaluation of the CDK4/6 inhibitor palbociclib in combination with a PI3K or MEK inhibitor in colorectal cancer

PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor—positive breast cancer

Incidence and Outcome of BRCA Mutations in Unselected Patients with Triple Receptor-Negative Breast Cancer

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

Mammary angiosarcomas: imaging findings in 24 patients

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