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Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells

Cancer research (Chicago, Ill.), 2017-03, Vol.77 (6), p.1453-1464

2017

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Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein

Pharmacology & therapeutics (Oxford), 2015-09, Vol.153, p.25-35

2015

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Mitochondrial reactive oxygen species affect sensitivity to curcumin-induced apoptosis

Free radical biology & medicine, 2008-04, Vol.44 (7), p.1382-1393

Hail, Numsen

2008

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Apoptosis as a Novel Target for Cancer Chemoprevention

JNCI : Journal of the National Cancer Institute, 2004-05, Vol.96 (9), p.662-672

2004

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The CXCR4 antagonist AMD3465 regulates oncogenic signaling and invasiveness in vitro and prevents breast cancer growth and metastasis in vivo

PloS one, 2013-03, Vol.8 (3), p.e58426

2013

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Teriflunomide (Leflunomide) Promotes Cytostatic, Antioxidant, and Apoptotic Effects in Transformed Prostate Epithelial Cells: Evidence Supporting a Role for Teriflunomide in Prostate Cancer Chemoprevention

Neoplasia (New York, N.Y.), 2010-06, Vol.12 (6), p.464-475

2010

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Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

Haematologica (Roma), 2018-05, Vol.103 (5), p.810

2018

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Cancer chemoprevention and mitochondria: Targeting apoptosis in transformed cells via the disruption of mitochondrial bioenergetics/redox state

Molecular nutrition & food research, 2009-01, Vol.53 (1), p.49-67

2009

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Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells

Biochimica et biophysica acta, 2016-04, Vol.1863 (4), p.562-571

2016

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Simultaneous inhibition of PDK1/AKT and fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia

Cancer research (Chicago, Ill.), 2006-04, Vol.66 (7), p.3737-3746

2006

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Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia

Blood, 2016-09, Vol.128 (9), p.1260-1269

2016

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Mitochondrial uncoupling and the reprograming of intermediary metabolism in leukemia cells

Frontiers in oncology, 2013-01, Vol.3, p.67-67

2013

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IKK inhibition by BMS-345541 suppresses breast tumorigenesis and metastases by targeting GD2+ cancer stem cells

Oncotarget, 2017-06, Vol.8 (23), p.36936-36949

2017

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Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes

Molecular pharmacology, 2011-06, Vol.79 (6), p.941-952

2011

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Cancer chemoprevention: A radical perspective

Free radical biology & medicine, 2008-07, Vol.45 (2), p.97-110

2008

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Examining the Role of Mitochondrial Respiration in Vanilloid-Induced Apoptosis

JNCI : Journal of the National Cancer Institute, 2002-09, Vol.94 (17), p.1281-1292

2002

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Selective apoptosis induction by the cancer chemopreventive agent N-(4-hydroxyphenyl)retinamide is achieved by modulating mitochondrial bioenergetics in premalignant and malignant human prostate epithelial cells

Apoptosis (London), 2009-07, Vol.14 (7), p.849-863

2009

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2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) Directly Targets Mitochondrial Glutathione to Induce Apoptosis in Pancreatic Cancer

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.36273-36282

2005

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Evidence supporting a role for dihydroorotate dehydrogenase, bioenergetics, and p53 in selective teriflunomide-induced apoptosis in transformed versus normal human keratinocytes

Apoptosis (London), 2012-03, Vol.17 (3), p.258-268

2012

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Role of MSC-derived galectin 3 in the AML microenvironment

Biochimica et biophysica acta. Molecular cell research, 2018-07, Vol.1865 (7), p.959-969

2018

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Mechanisms of vanilloid-induced apoptosis

Apoptosis (London), 2003-06, Vol.8 (3), p.251-262

HAIL, Numsen JR

2003

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Role of Mesenchymal Stem Cell Galectin 3 in the AML Tumor Microenvironment

Blood, 2015-12, Vol.126 (23), p.1198-1198

2015

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The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells

Biochimica et biophysica acta, 2014-09, Vol.1843 (9), p.1969-1977

2014

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Lactoferrin protects against acetaminophen‐induced liver injury in mice

Hepatology (Baltimore, Md.), 2010-03, Vol.51 (3), p.1007-1016

2010

Volltextzugriff (PDF)

Evidence supporting a role for dihydroorotate dehydrogenase, bioenergetics, and p53 in selective teriflunomide-induced apoptosis in transformed versus normal human keratinocytes

Apoptosis (London), 2012-03, Vol.17 (3), p.258-268

2012

Volltextzugriff (PDF)

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Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells

Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein

Mitochondrial reactive oxygen species affect sensitivity to curcumin-induced apoptosis

Apoptosis as a Novel Target for Cancer Chemoprevention

The CXCR4 antagonist AMD3465 regulates oncogenic signaling and invasiveness in vitro and prevents breast cancer growth and metastasis in vivo

Teriflunomide (Leflunomide) Promotes Cytostatic, Antioxidant, and Apoptotic Effects in Transformed Prostate Epithelial Cells: Evidence Supporting a Role for Teriflunomide in Prostate Cancer Chemoprevention

Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

Cancer chemoprevention and mitochondria: Targeting apoptosis in transformed cells via the disruption of mitochondrial bioenergetics/redox state

Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells

Simultaneous inhibition of PDK1/AKT and fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia

Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia

Mitochondrial uncoupling and the reprograming of intermediary metabolism in leukemia cells

IKK inhibition by BMS-345541 suppresses breast tumorigenesis and metastases by targeting GD2+ cancer stem cells

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes

Cancer chemoprevention: A radical perspective

Examining the Role of Mitochondrial Respiration in Vanilloid-Induced Apoptosis

Selective apoptosis induction by the cancer chemopreventive agent N-(4-hydroxyphenyl)retinamide is achieved by modulating mitochondrial bioenergetics in premalignant and malignant human prostate epithelial cells

2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) Directly Targets Mitochondrial Glutathione to Induce Apoptosis in Pancreatic Cancer

Evidence supporting a role for dihydroorotate dehydrogenase, bioenergetics, and p53 in selective teriflunomide-induced apoptosis in transformed versus normal human keratinocytes

Role of MSC-derived galectin 3 in the AML microenvironment

Mechanisms of vanilloid-induced apoptosis

Role of Mesenchymal Stem Cell Galectin 3 in the AML Tumor Microenvironment

The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells

Lactoferrin protects against acetaminophen‐induced liver injury in mice

Evidence supporting a role for dihydroorotate dehydrogenase, bioenergetics, and p53 in selective teriflunomide-induced apoptosis in transformed versus normal human keratinocytes

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