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Notch signaling in development and disease

Clinical genetics, 2003-12, Vol.64 (6), p.461-472

2003

Volltextzugriff (PDF)

Biological and therapeutic implications of a unique subtype of NPM1 mutated AML

Nature communications, 2021-02, Vol.12 (1), p.1054-13, Article 1054

2021

Volltextzugriff (PDF)

Requirement for Notch1 signals at sequential early stages of intrathymic T cell development

Nature Immunology, 2005-07, Vol.6 (7), p.671-679

2005

Volltextzugriff (PDF)

ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection

Immunological reviews, 2006-02, Vol.209 (1), p.142-158

2006

Volltextzugriff (PDF)

Subversion of the T/B Lineage Decision in the Thymus by Lunatic Fringe-Mediated Inhibition of Notch-1

Immunity (Cambridge, Mass.), 2001-08, Vol.15 (2), p.225-236

2001

Volltextzugriff (PDF)

Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions

Immunological reviews, 2006-02, Vol.209 (1), p.76-94

2006

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V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors

Genes & development, 1996-08, Vol.10 (16), p.2038-2054

1996

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The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice

Cancer cell, 2003, Vol.3 (1), p.37-50

2003

Volltextzugriff (PDF)

Notch signaling in lymphocyte development

Seminars in immunology, 2002-12, Vol.14 (6), p.395-404

Guidos, Cynthia J

2002

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Fyn Can Partially Substitute for Lck in T Lymphocyte Development

Immunity (Cambridge, Mass.), 1996-11, Vol.5 (5), p.417-428

1996

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Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

Molecular and Cellular Biology, 1996-10, Vol.16 (10), p.5507-5517

1996

Volltextzugriff (PDF)

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

Nature genetics, 1996-04, Vol.12 (4), p.448-451

1996

Volltextzugriff (PDF)

Transgenic Expression of Numb Inhibits Notch Signaling in Immature Thymocytes But Does Not Alter T Cell Fate Specification

The Journal of immunology (1950), 2002-04, Vol.168 (7), p.3173-3180

2002

Volltextzugriff (PDF)

Positive selection of CD4 + and CD8 + T cells

Current opinion in immunology, 1996-04, Vol.8 (2), p.225-232

Guidos, Cynthia J

1996

Volltextzugriff (PDF)

Rescue of T Cell-Specific V(D)J Recombination in SCID Mice by DNA-Damaging Agents

Science (American Association for the Advancement of Science), 1994-10, Vol.266 (5184), p.450-455

1994

Volltextzugriff (PDF)

Fine-tuning Notch1 activation by endocytosis and glycosylation

Seminars in immunology, 2003-04, Vol.15 (2), p.99-106

2003

Volltextzugriff (PDF)

TCR engagement of CD4+CD8+ thymocytes in vitro induces early aspects of positive selection, but not apoptosis

The Journal of immunology (1950), 1997-01, Vol.158 (1), p.65

1997

Volltextzugriff (PDF)

Irradiation Promotes V(D)J Joining and RAG-Dependent Neoplastic Transformation in SCID T-Cell Precursors

Molecular and Cellular Biology, 2001-01, Vol.21 (2), p.400-413

2001

Volltextzugriff (PDF)

Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway

The Journal of experimental medicine, 1995-03, Vol.181 (3), p.1187-1195

1995

Volltextzugriff (PDF)

In vitro maturation of clonal CD4+CD8+ cell lines in response to TCR engagement

The Journal of immunology (1950), 1995-05, Vol.154 (10), p.5011

1995

Volltextzugriff (PDF)

The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk : A severe combined immune deficiency (SCID) murine model

Cancer research (Chicago, Ill.), 1997-10, Vol.57 (19), p.4408-4413

1997

Volltextzugriff (PDF)

Developmental potential of CD4-8- thymocytes. Peripheral progeny include mature CD4-8- T cells bearing alpha beta T cell receptor

The Journal of immunology (1950), 1989-06, Vol.142 (11), p.3773

1989

Volltextzugriff (PDF)

Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice

The Journal of experimental medicine, 1996-08, Vol.184 (2), p.419-428

1996

Volltextzugriff (PDF)

Lck dependence of signaling pathways activated by γirradiation and CD3ε engagement in RAG-1-/-immature thymocytes

International immunology, 1996-07, Vol.8 (7), p.1159-1164

1996

Volltextzugriff (PDF)

Developmental analysis of the mouse hematolymphoid system

Cold Spring Harbor Symposia on Quantitative Biology, 1989, Vol.54 Pt 1, p.75

1989

Volltextzugriff (PDF)

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Notch signaling in development and disease

Biological and therapeutic implications of a unique subtype of NPM1 mutated AML

Requirement for Notch1 signals at sequential early stages of intrathymic T cell development

ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection

Subversion of the T/B Lineage Decision in the Thymus by Lunatic Fringe-Mediated Inhibition of Notch-1

Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors

The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice

Notch signaling in lymphocyte development

Fyn Can Partially Substitute for Lck in T Lymphocyte Development

Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

Transgenic Expression of Numb Inhibits Notch Signaling in Immature Thymocytes But Does Not Alter T Cell Fate Specification

Positive selection of CD4 + and CD8 + T cells

Rescue of T Cell-Specific V(D)J Recombination in SCID Mice by DNA-Damaging Agents

Fine-tuning Notch1 activation by endocytosis and glycosylation

TCR engagement of CD4+CD8+ thymocytes in vitro induces early aspects of positive selection, but not apoptosis

Irradiation Promotes V(D)J Joining and RAG-Dependent Neoplastic Transformation in SCID T-Cell Precursors

Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway

In vitro maturation of clonal CD4+CD8+ cell lines in response to TCR engagement

The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk : A severe combined immune deficiency (SCID) murine model

Developmental potential of CD4-8- thymocytes. Peripheral progeny include mature CD4-8- T cells bearing alpha beta T cell receptor

Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice

Lck dependence of signaling pathways activated by γirradiation and CD3ε engagement in RAG-1-/-immature thymocytes

Developmental analysis of the mouse hematolymphoid system

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