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A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Left Ventricular Outflow Tract Obstruction in Feline Hypertrophic Cardiomyopathy

PloS one, 2016-12, Vol.11 (12), p.e0168407

2016

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A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6273), p.617-621

2016

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Canine urinary bladder transitional cell carcinoma tumor volume is dependent on imaging modality and measurement technique

Veterinary radiology & ultrasound, 2018-11, Vol.59 (6), p.767-776

2018

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PIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell death

The Journal of cell biology, 2009-10, Vol.187 (2), p.279-294

2009

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Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (35), p.E8143-E8152

2018

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Severe polycystic liver disease in a cat

JFMS open reports, 2023-07, Vol.9 (2), p.20551169231216859

2023

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Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)

Circulation (New York, N.Y.), 2018-10, Vol.138 (14), p.1387-1398

2018

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Characterization of WWOX expression and function in canine mast cell tumors and malignant mast cell lines

BMC veterinary research, 2020-10, Vol.16 (1), p.415-13, Article 415

2020

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Using Digital Health Technology to Better Generate Evidence and Deliver Evidence-Based Care

Journal of the American College of Cardiology, 2018-06, Vol.71 (23), p.2680-2690

2018

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A pilot study of toceranib/vinblastine therapy for canine transitional cell carcinoma

BMC veterinary research, 2016-11, Vol.12 (1), p.257-257, Article 257

2016

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Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation

Proceedings of the National Academy of Sciences - PNAS, 2016-06, Vol.113 (24), p.6701-6706

2016

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First-in-Human Evaluation of Safety, Pharmacokinetics and Muscle Glycogen Lowering of a Novel Glycogen Synthase 1 Inhibitor for the Treatment of Pompe Disease

Clinical pharmacology and therapeutics, 2024-10

2024

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Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

Cell, 2009-10, Vol.139 (2), p.380-392

2009

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Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11), p.1889-1899

2023

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Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease

American journal of physiology: endocrinology and metabolism, 2024-10, Vol.327 (4), p.E524-E532

2024

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Discordant clinical features of identical hypertrophic cardiomyopathy twins

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (10), p.1-5

2021

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Incident Atrial Fibrillation Is Associated With MYH7 Sarcomeric Gene Variation in Hypertrophic Cardiomyopathy

Circulation. Heart failure, 2018-09, Vol.11 (9), p.e005191-e005191

2018

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Regulation of expression of murine transferrin receptor 2

Blood, 2001-09, Vol.98 (6), p.1949-1954

2001

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Proteins and small molecules for cellular regenerative medicine

Physiological reviews, 2013-01, Vol.93 (1), p.311-325

2013

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Utility of cardiac MRI to diagnose myocardial ischemia and fibrosis in dogs with cardiomegaly secondary to myxomatous mitral valve disease

American journal of veterinary research, 2022-10, Vol.83 (10)

2022

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Care in Specialized Centers and Data Sharing Increase Agreement in Hypertrophic Cardiomyopathy Genetic Test Interpretation

Circulation. Cardiovascular genetics, 2017-10, Vol.10 (5)

2017

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Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders

Science translational medicine, 2024-01, Vol.16 (730), p.eadf1691

2024

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Percutaneous microwave ablation of solitary presumptive pulmonary metastases in two dogs with appendicular osteosarcoma

Veterinary surgery, 2020-08, Vol.49 (6), p.1174-1182

2020

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Intra- and inter-rater reliability in the cross-sectional area of feline lumbar epaxial musculature evaluated via abdominal CT scan

Journal of feline medicine and surgery, 2020-08, Vol.22 (8), p.721-728

2020

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A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Left Ventricular Outflow Tract Obstruction in Feline Hypertrophic Cardiomyopathy

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A

Canine urinary bladder transitional cell carcinoma tumor volume is dependent on imaging modality and measurement technique

PIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell death

Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers

Severe polycystic liver disease in a cat

Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)

Characterization of WWOX expression and function in canine mast cell tumors and malignant mast cell lines

Using Digital Health Technology to Better Generate Evidence and Deliver Evidence-Based Care

A pilot study of toceranib/vinblastine therapy for canine transitional cell carcinoma

Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation

First-in-Human Evaluation of Safety, Pharmacokinetics and Muscle Glycogen Lowering of a Novel Glycogen Synthase 1 Inhibitor for the Treatment of Pompe Disease

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease

Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease

Discordant clinical features of identical hypertrophic cardiomyopathy twins

Incident Atrial Fibrillation Is Associated With MYH7 Sarcomeric Gene Variation in Hypertrophic Cardiomyopathy

Regulation of expression of murine transferrin receptor 2

Proteins and small molecules for cellular regenerative medicine

Utility of cardiac MRI to diagnose myocardial ischemia and fibrosis in dogs with cardiomegaly secondary to myxomatous mitral valve disease

Care in Specialized Centers and Data Sharing Increase Agreement in Hypertrophic Cardiomyopathy Genetic Test Interpretation

Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders

Percutaneous microwave ablation of solitary presumptive pulmonary metastases in two dogs with appendicular osteosarcoma

Intra- and inter-rater reliability in the cross-sectional area of feline lumbar epaxial musculature evaluated via abdominal CT scan

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