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Combinatorial compound libraries for drug discovery: an ongoing challenge

Nature reviews. Drug discovery, 2003-03, Vol.2 (3), p.222-230

2003

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Comparison of Competitive Radioimmunoassays and Two-Site Sandwich Assays for the Measurement and Interpretation of Plasma Ghrelin Levels

The journal of clinical endocrinology and metabolism, 2010-05, Vol.95 (5), p.2351-2358

2010

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Evidence for Acyl-Ghrelin Modulation of Growth Hormone Release in the Fed State

The journal of clinical endocrinology and metabolism, 2008-05, Vol.93 (5), p.1988-1994

2008

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Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody

Biochemical journal, 2006-05, Vol.395 (3), p.473-481

2006

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Novel Ghrelin Assays Provide Evidence for Independent Regulation of Ghrelin Acylation and Secretion in Healthy Young Men

The journal of clinical endocrinology and metabolism, 2008-05, Vol.93 (5), p.1980-1987

2008

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Characterization of an Inkjet Chemical Microdispenser for Combinatorial Library Synthesis

Analytical chemistry (Washington), 1997-02, Vol.69 (4), p.543-551

1997

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Design, synthesis, and evaluation of novel small molecule inhibitors of the influenza virus protein NS1

Bioorganic & medicinal chemistry, 2012-01, Vol.20 (1), p.487-497

2012

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Evidence for Immune Selection of Hepatitis C Virus (HCV) Putative Envelope Glycoprotein Variants: Potential Role in Chronic HCV Infections

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (8), p.3468-3472

1992

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Novel inhibitor of influenza non-structural protein 1 blocks multi-cycle replication in an RNase L-dependent manner

Journal of general virology, 2011-01, Vol.92 (Pt 1), p.60-70

2011

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Homo-cysteinyl peptide inhibitors of the L1 metallo-β-lactamase, and SAR as determined by combinatorial library synthesis

Bioorganic & medicinal chemistry letters, 2006-10, Vol.16 (19), p.5169-5175

2006

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Diversity Space and Its Application to Library Selection and Design

Journal of chemical information and modeling, 2006-07, Vol.46 (4), p.1588-1597

2006

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Disruption of the determinant hierarchy on a self-MHC peptide: concomitant tolerance induction to the dominant determinant and priming to the cryptic self-determinant

International immunology, 1994-01, Vol.6 (1), p.131-138

1994

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A new o-nitrobenzyl photocleavable linker for solid phase synthesis

Tetrahedron letters, 1997-11, Vol.38 (44), p.7653-7656

1997

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A single-bead decode strategy using electrospray ionization mass spectrometry and a new photolabile linker: 3-amino-3-(2-nitrophenyl)propionic acid

Molecular diversity, 1995-09, Vol.1 (1), p.4-12

1995

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Single Bead Characterization Using Analytical Constructs: Application to Quality Control of Libraries

Analytical chemistry (Washington), 2001-03, Vol.73 (5), p.963-970

2001

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Chemistry of Antibody Binding to a Protein

Science (American Association for the Advancement of Science), 1987-03, Vol.235 (4793), p.1184-1190

1987

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Mechanisms of Antibody Binding to a Protein

Science (American Association for the Advancement of Science), 1987-03, Vol.235 (4793), p.1191-1196

1987

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Binding of synthetic peptides by a human monoclonal IgM with an unusual combining site structure

Journal of molecular recognition, 2001-07, Vol.14 (4), p.229-238

2001

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Positive ϕ angles can strengthen hydrogen bonding in turn structures

The FASEB journal, 2011-04, Vol.25, p.759.1-759.1

2011

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Altering the Antigenicity of Proteins

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (8), p.3352-3356

1992

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Survey of the Diversity Space Coverage of Reported Combinatorial Libraries

Journal of combinatorial chemistry, 2007-07, Vol.9 (4), p.724-734

2007

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Strategies for epitope analysis using peptide synthesis

Journal of immunological methods, 1987-09, Vol.102 (2), p.259-274

1987

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High-throughput purity estimation and characterisation of synthetic peptides by electrospray mass spectrometry

International Journal of Peptide and Protein Research, 1996-01, Vol.47 (1-2), p.47-55

1996

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Identification of B-epitopes in the human papillomavirus 18 E7 open reading frame protein

The Journal of immunology (1950), 1990-11, Vol.145 (9), p.3105-3110

1990

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Mapping the major human T helper epitopes of tetanus toxin. The emerging picture

The Journal of immunology (1950), 1993-12, Vol.151 (11), p.6175-6184

1993

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Combinatorial compound libraries for drug discovery: an ongoing challenge

Comparison of Competitive Radioimmunoassays and Two-Site Sandwich Assays for the Measurement and Interpretation of Plasma Ghrelin Levels

Evidence for Acyl-Ghrelin Modulation of Growth Hormone Release in the Fed State

Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody

Novel Ghrelin Assays Provide Evidence for Independent Regulation of Ghrelin Acylation and Secretion in Healthy Young Men

Characterization of an Inkjet Chemical Microdispenser for Combinatorial Library Synthesis

Design, synthesis, and evaluation of novel small molecule inhibitors of the influenza virus protein NS1

Evidence for Immune Selection of Hepatitis C Virus (HCV) Putative Envelope Glycoprotein Variants: Potential Role in Chronic HCV Infections

Novel inhibitor of influenza non-structural protein 1 blocks multi-cycle replication in an RNase L-dependent manner

Homo-cysteinyl peptide inhibitors of the L1 metallo-β-lactamase, and SAR as determined by combinatorial library synthesis

Diversity Space and Its Application to Library Selection and Design

Disruption of the determinant hierarchy on a self-MHC peptide: concomitant tolerance induction to the dominant determinant and priming to the cryptic self-determinant

A new o-nitrobenzyl photocleavable linker for solid phase synthesis

A single-bead decode strategy using electrospray ionization mass spectrometry and a new photolabile linker: 3-amino-3-(2-nitrophenyl)propionic acid

Single Bead Characterization Using Analytical Constructs: Application to Quality Control of Libraries

Chemistry of Antibody Binding to a Protein

Mechanisms of Antibody Binding to a Protein

Binding of synthetic peptides by a human monoclonal IgM with an unusual combining site structure

Positive ϕ angles can strengthen hydrogen bonding in turn structures

Altering the Antigenicity of Proteins

Survey of the Diversity Space Coverage of Reported Combinatorial Libraries

Strategies for epitope analysis using peptide synthesis

High-throughput purity estimation and characterisation of synthetic peptides by electrospray mass spectrometry

Identification of B-epitopes in the human papillomavirus 18 E7 open reading frame protein

Mapping the major human T helper epitopes of tetanus toxin. The emerging picture

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