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Pathological Interface Between Oligomeric Alpha-Synuclein and Tau in Synucleinopathies

Biological psychiatry (1969), 2015-11, Vol.78 (10), p.672-683

2015

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The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration

Aging cell, 2015-10, Vol.14 (5), p.715-724

2015

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Formation and propagation of tau oligomeric seeds

Frontiers in neurology, 2013-01, Vol.4, p.93

2013

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Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy

Molecular neurodegeneration, 2018-03, Vol.13 (1), p.13-13, Article 13

2018

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Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (44), p.E10495-E10504

2018

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Advances in Therapeutics for Neurodegenerative Tauopathies: Moving toward the Specific Targeting of the Most Toxic Tau Species

ACS chemical neuroscience, 2014-09, Vol.5 (9), p.752-769

2014

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Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity

Neurobiology of disease, 2020-09, Vol.143, p.105016-105016, Article 105016

2020

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Ubiquilin-2 regulates pathological alpha-synuclein

Scientific reports, 2023-01, Vol.13 (1), p.293-14, Article 293

2023

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Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies

Aging and disease, 2017-06, Vol.8 (3), p.257-266

2017

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Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

Scientific reports, 2021-01, Vol.11 (1), p.287-13, Article 287

2021

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Potential mechanisms and implications for the formation of tau oligomeric strains

Critical reviews in biochemistry and molecular biology, 2016-11, Vol.51 (6), p.482-496

2016

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Characterization of tau oligomeric seeds in progressive supranuclear palsy

Acta neuropathologica communications, 2014-06, Vol.2 (1), p.73, Article 73

2014

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The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes

Acta neuropathologica communications, 2014-05, Vol.2 (1), p.56-56, Article 56

2014

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Tau Oligomers as Pathogenic Seeds: Preparation and Propagation In Vitro and In Vivo

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1523, p.141

2017

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α-Synuclein Oligomers Induce a Unique Toxic Tau Strain

Biological psychiatry (1969), 2018-10, Vol.84 (7), p.499-508

2018

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Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases

Journal of Alzheimer's disease, 2017-01, Vol.55 (3), p.1083

2017

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Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles

The Journal of neuroscience, 2014-03, Vol.34 (12), p.4260-4272

2014

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Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds

Journal of Alzheimer's disease, 2014-01, Vol.40 Suppl 1, p.S97

2014

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Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy

The Journal of neuroscience, 2022-03, Vol.42 (9), p.1845-1863

2022

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AAV2-mediated GRP78 Transfer Alleviates Retinal Neuronal Injury by Downregulating ER Stress and Tau Oligomer Formation

Investigative ophthalmology & visual science, 2018-09, Vol.59 (11), p.4670-4682

2018

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Nature-inspired design and evolution of anti-amyloid antibodies

The Journal of biological chemistry, 2019-05, Vol.294 (21), p.8438-8451

2019

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Harmine treatment enhances short-term memory in old rats: Dissociation of cognition and the ability to perform the procedural requirements of maze testing

Physiology & behavior, 2015-01, Vol.138, p.260-265

2015

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Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity

The Journal of biological chemistry, 2021-01, Vol.296, p.100508, Article 100508

2021

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Oligomer Formation and Cross‐Seeding: The New Frontier

Israel journal of chemistry, 2017-07, Vol.57 (7-8), p.665-673

2017

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Ubiquilin-2 differentially regulates polyglutamine disease proteins

Human molecular genetics, 2020-08, Vol.29 (15), p.2596-2610

2020

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Pathological Interface Between Oligomeric Alpha-Synuclein and Tau in Synucleinopathies

The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration

Formation and propagation of tau oligomeric seeds

Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy

Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly

Advances in Therapeutics for Neurodegenerative Tauopathies: Moving toward the Specific Targeting of the Most Toxic Tau Species

Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity

Ubiquilin-2 regulates pathological alpha-synuclein

Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies

Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

Potential mechanisms and implications for the formation of tau oligomeric strains

Characterization of tau oligomeric seeds in progressive supranuclear palsy

The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes

Tau Oligomers as Pathogenic Seeds: Preparation and Propagation In Vitro and In Vivo

α-Synuclein Oligomers Induce a Unique Toxic Tau Strain

Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases

Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles

Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds

Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy

AAV2-mediated GRP78 Transfer Alleviates Retinal Neuronal Injury by Downregulating ER Stress and Tau Oligomer Formation

Nature-inspired design and evolution of anti-amyloid antibodies

Harmine treatment enhances short-term memory in old rats: Dissociation of cognition and the ability to perform the procedural requirements of maze testing

Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity

Oligomer Formation and Cross‐Seeding: The New Frontier

Ubiquilin-2 differentially regulates polyglutamine disease proteins

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