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Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies

Cancer research (Chicago, Ill.), 2005-02, Vol.65 (3), p.671-680

2005

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The biology of VEGF and its receptors

Nature medicine, 2003-06, Vol.9 (6), p.669-676

2003

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Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

Nature reviews. Drug discovery, 2004-05, Vol.3 (5), p.391-400

2004

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Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis

Cancer cell, 2004-11, Vol.6 (5), p.485-495

2004

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HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation

Cell, 2003-03, Vol.112 (5), p.645-657

2003

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The Vascular Basement Membrane: A Niche for Insulin Gene Expression and β Cell Proliferation

Developmental cell, 2006-03, Vol.10 (3), p.397-405

2006

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Vascular Endothelial Growth Factor Expression in the Retinal Pigment Epithelium Is Essential for Choriocapillaris Development and Visual Function

The American journal of pathology, 2005-11, Vol.167 (5), p.1451-1459

2005

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Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

The Journal of clinical investigation, 2003-03, Vol.111 (5), p.707-716

2003

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Cross-species Vascular Endothelial Growth Factor (VEGF)-blocking Antibodies Completely Inhibit the Growth of Human Tumor Xenografts and Measure the Contribution of Stromal VEGF

The Journal of biological chemistry, 2006-01, Vol.281 (2), p.951-961

2006

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Angiogenesis-Independent Endothelial Protection of Liver: Role of VEGFR-1

Science (American Association for the Advancement of Science), 2003-02, Vol.299 (5608), p.890-893

2003

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The hypoxic response of tumors is dependent on their microenvironment

Cancer cell, 2003-08, Vol.4 (2), p.133-146

2003

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Vascular Endothelial Growth Factor Induces Expression of the Antiapoptotic Proteins Bcl-2 and A1 in Vascular Endothelial Cells

The Journal of biological chemistry, 1998-05, Vol.273 (21), p.13313-13316

1998

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VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic β cell carcinogenesis

Cancer cell, 2002-03, Vol.1 (2), p.193-202

2002

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Role of VEGF-A in Vascularization of Pancreatic Islets

Current biology, 2003-06, Vol.13 (12), p.1070-1074

2003

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Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback

Development (Cambridge), 2005-03, Vol.132 (5), p.941-952

2005

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VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

Nature medicine, 1999-06, Vol.5 (6), p.623-628

1999

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VEGF-null cells require PDGFR α signaling-mediated stromal fibroblast recruitment for tumorigenesis

The EMBO journal, 2004-07, Vol.23 (14), p.2800-2810

2004

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The role of VEGF in normal and neoplastic hematopoiesis

Journal of molecular medicine (Berlin, Germany), 2003-01, Vol.81 (1), p.20-31

2003

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Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

The Journal of biological chemistry, 1998-11, Vol.273 (46), p.30336-30343

1998

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VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

Nature (London), 2002-06, Vol.417 (6892), p.954-958

2002

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Angiogenesis and Bone Growth

Trends in cardiovascular medicine, 2000-07, Vol.10 (5), p.223-228

2000

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Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia

The Journal of biological chemistry, 1997-09, Vol.272 (38), p.23659-23667

1997

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VEGF is required for growth and survival in neonatal mice

Development (Cambridge), 1999-03, Vol.126 (6), p.1149-1159

1999

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Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor

Thrombosis and haemostasis, 2004-03, Vol.91 (3), p.595-605

2004

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The Role of Vascular Endothelial Growth Factor in Angiogenesis

Acta haematologica, 2001-01, Vol.106 (4), p.148-156

2001

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Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies

The biology of VEGF and its receptors

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis

HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation

The Vascular Basement Membrane: A Niche for Insulin Gene Expression and β Cell Proliferation

Vascular Endothelial Growth Factor Expression in the Retinal Pigment Epithelium Is Essential for Choriocapillaris Development and Visual Function

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

Cross-species Vascular Endothelial Growth Factor (VEGF)-blocking Antibodies Completely Inhibit the Growth of Human Tumor Xenografts and Measure the Contribution of Stromal VEGF

Angiogenesis-Independent Endothelial Protection of Liver: Role of VEGFR-1

The hypoxic response of tumors is dependent on their microenvironment

Vascular Endothelial Growth Factor Induces Expression of the Antiapoptotic Proteins Bcl-2 and A1 in Vascular Endothelial Cells

VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic β cell carcinogenesis

Role of VEGF-A in Vascularization of Pancreatic Islets

Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

VEGF-null cells require PDGFR α signaling-mediated stromal fibroblast recruitment for tumorigenesis

The role of VEGF in normal and neoplastic hematopoiesis

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

Angiogenesis and Bone Growth

Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia

VEGF is required for growth and survival in neonatal mice

Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor

The Role of Vascular Endothelial Growth Factor in Angiogenesis

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