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Protein Posttranslational Modifications: The Chemistry of Proteome Diversifications

Angewandte Chemie International Edition, 2005-12, Vol.44 (45), p.7342-7372

2005

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Biochemical and functional characterization of the p.A165T missense variant of mitochondrial amidoxime-reducing component 1

The Journal of biological chemistry, 2024-06, Vol.300 (6), p.107353, Article 107353

2024

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Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

Cell reports (Cambridge), 2019-11, Vol.29 (6), p.1675-1689.e9

2019

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Long-acting biodegradable implant for sustained delivery of antiretrovirals (ARVs) and hormones

Journal of controlled release, 2021-12, Vol.340, p.188-199

2021

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Stryer Biochemie

7th Aufl 2013rd edition, 2017

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Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B‑Raf

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.15651-15670

2021

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4,6-Diaminopyrimidines as Highly Preferred Troponin I‑Interacting Kinase (TNNI3K) Inhibitors

Journal of medicinal chemistry, 2018-04, Vol.61 (7), p.3076-3088

2018

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Substituent Effects on Drug–Receptor H‑bond Interactions: Correlations Useful for the Design of Kinase Inhibitors

Journal of medicinal chemistry, 2016-12, Vol.59 (23), p.10629-10641

2016

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Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart

Science translational medicine, 2013-10, Vol.5 (207), p.207ra141

2013

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Identification of Purines and 7‑Deazapurines as Potent and Selective Type I Inhibitors of Troponin I‑Interacting Kinase (TNNI3K)

Journal of medicinal chemistry, 2015-09, Vol.58 (18), p.7431-7448

2015

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Biosynthesis of Pipecolic Acid by RapL, a Lysine Cyclodeaminase Encoded in the Rapamycin Gene Cluster

Journal of the American Chemical Society, 2006-03, Vol.128 (11), p.3838-3847

2006

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High FGF23 Levels Failed to Predict Cardiac Hypertrophy in Animal Models of Hyperphosphatemia and Chronic Renal Failure

Journal of the Endocrine Society, 2021-08, Vol.5 (8), p.bvab066-bvab066

2021

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GSK114: A selective inhibitor for elucidating the biological role of TNNI3K

Bioorganic & medicinal chemistry letters, 2016-07, Vol.26 (14), p.3355-3358

2016

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NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation

Journal of enzyme inhibition and medicinal chemistry, 2013-02, Vol.28 (1), p.95-104

2013

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Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5

Nature structural & molecular biology, 2000-12, Vol.7 (12), p.1091-1095

2000

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The Design of Functional DNA-Binding Proteins Based on Zinc Finger Domains

Chemical reviews, 2004-02, Vol.104 (2), p.789-800

2004

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Pharmacokinetic Study of Islatravir and Etonogestrel Implants in Macaques

Pharmaceutics, 2023-11, Vol.15 (12), p.2676

2023

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Dose‐response effect of eribulin in preclinical models of osteosarcoma by the pediatric preclinical testing consortium

Pediatric blood & cancer, 2020-10, Vol.67 (10), p.e28606-n/a

2020

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Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

Journal of the American Heart Association, 2017-05, Vol.6 (5)

2017

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Novel nicotinic acetylcholine receptor agonists containing carbonyl moiety as a hydrogen bond acceptor

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (13), p.3927-3934

2013

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Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats

Psychopharmacologia, 2012-10, Vol.223 (3), p.251-258

2012

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Pex5p binding affinities for canonical and noncanonical PTS1 peptides

Proteins, structure, function, and bioinformatics, 2004-06, Vol.55 (4), p.856-861

2004

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Elucidating the Substrate Specificity and Condensation Domain Activity of FkbP, the FK520 Pipecolate-Incorporating Enzyme

Biochemistry (Easton), 2005-04, Vol.44 (16), p.5993-6002

2005

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Discovery of 3‑(5-Chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a Novel Highly Selective α4β2 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders

Journal of medicinal chemistry, 2012-11, Vol.55 (21), p.9181-9194

2012

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Development of a High-Throughput Cell-Based Assay for Superoxide Production in HL-60 Cells

Journal of biomolecular screening, 2010-04, Vol.15 (4), p.388-397

2010

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Protein Posttranslational Modifications: The Chemistry of Proteome Diversifications

Biochemical and functional characterization of the p.A165T missense variant of mitochondrial amidoxime-reducing component 1

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

Long-acting biodegradable implant for sustained delivery of antiretrovirals (ARVs) and hormones

Stryer Biochemie

Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B‑Raf

4,6-Diaminopyrimidines as Highly Preferred Troponin I‑Interacting Kinase (TNNI3K) Inhibitors

Substituent Effects on Drug–Receptor H‑bond Interactions: Correlations Useful for the Design of Kinase Inhibitors

Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart

Identification of Purines and 7‑Deazapurines as Potent and Selective Type I Inhibitors of Troponin I‑Interacting Kinase (TNNI3K)

Biosynthesis of Pipecolic Acid by RapL, a Lysine Cyclodeaminase Encoded in the Rapamycin Gene Cluster

High FGF23 Levels Failed to Predict Cardiac Hypertrophy in Animal Models of Hyperphosphatemia and Chronic Renal Failure

GSK114: A selective inhibitor for elucidating the biological role of TNNI3K

NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation

Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5

The Design of Functional DNA-Binding Proteins Based on Zinc Finger Domains

Pharmacokinetic Study of Islatravir and Etonogestrel Implants in Macaques

Dose‐response effect of eribulin in preclinical models of osteosarcoma by the pediatric preclinical testing consortium

Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

Novel nicotinic acetylcholine receptor agonists containing carbonyl moiety as a hydrogen bond acceptor

Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats

Pex5p binding affinities for canonical and noncanonical PTS1 peptides

Elucidating the Substrate Specificity and Condensation Domain Activity of FkbP, the FK520 Pipecolate-Incorporating Enzyme

Discovery of 3‑(5-Chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a Novel Highly Selective α4β2 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders

Development of a High-Throughput Cell-Based Assay for Superoxide Production in HL-60 Cells

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