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THEMIS: a critical TCR signal regulator for ligand discrimination

Current opinion in immunology, 2015-04, Vol.33, p.86-92

2015

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Costimulatory Molecule DNAM-1 Is Essential for Optimal Differentiation of Memory Natural Killer Cells during Mouse Cytomegalovirus Infection

Immunity (Cambridge, Mass.), 2014-02, Vol.40 (2), p.225-234

2014

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Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

Nature, 2006-12, Vol.444 (7120), p.724-729

2006

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Fine-tuning T cell receptor signaling to control T cell development

Trends in immunology, 2014-07, Vol.35 (7), p.311-318

2014

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Signaling in thymic selection

Current opinion in immunology, 2011-04, Vol.23 (2), p.207-212

2011

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A THEMIS:SHP1 complex promotes T-cell survival

The EMBO journal, 2015-02, Vol.34 (3), p.393-409

2015

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A tryptophan metabolite made by a gut microbiome eukaryote induces pro‐inflammatory T cells

The EMBO journal, 2023-11, Vol.42 (21), p.e112963-n/a

2023

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GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development

The Journal of immunology (1950), 2013-04, Vol.190 (7), p.3749-3756

2013

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T Cell Receptor (TCR)-induced Tyrosine Phosphorylation Dynamics Identifies THEMIS as a New TCR Signalosome Component

The Journal of biological chemistry, 2011-03, Vol.286 (9), p.7535-7547

2011

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SHP1‐ing thymic selection

European journal of immunology, 2016-09, Vol.46 (9), p.2091-2094

2016

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Altered Peptide Ligands Induce Delayed CD8-T Cell Receptor Interaction—a Role for CD8 in Distinguishing Antigen Quality

Immunity (Cambridge, Mass.), 2006-08, Vol.25 (2), p.203-211

2006

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The Lupus-Related Lmb3 Locus Contains a Disease-Suppressing Coronin-1A Gene Mutation

Immunity (Cambridge, Mass.), 2008-01, Vol.28 (1), p.40-51

2008

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Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC

The Journal of experimental medicine, 2013-08, Vol.210 (9), p.1807-1821

2013

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Molecular engineering of a therapeutic antibody for Blo t 5–induced allergic asthma

Journal of allergy and clinical immunology, 2017-05, Vol.139 (5), p.1705-1708.e6

2017

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Themis controls T cell activation, effector functions, and metabolism of peripheral CD8 + T cells

Life science alliance, 2023-12, Vol.6 (12), p.e202302156

2023

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T Cell Receptor Structures: Three for the Price of One

Immunity (Cambridge, Mass.), 2011-07, Vol.35 (1), p.1-3

Gascoigne, Nicholas R.J.

2011

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T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state

The Journal of experimental medicine, 2007-10, Vol.204 (11), p.2747-2757

2007

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Hybrid structural modeling of alloantibody binding to human leukocyte antigen with rapid and reproducible cross-linking mass spectrometry

Cell reports methods, 2023-09, Vol.3 (9), p.100569-100569, Article 100569

2023

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Opinion: Do T cells need endogenous peptides for activation?

Nature reviews. Immunology, 2008-11, Vol.8 (11), p.895-900

Gascoigne, Nicholas RJ

2008

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Inhibition of T Cell Receptor-Coreceptor Interactions by Antagonist Ligands Visualized by Live FRET Imaging of the T-Hybridoma Immunological Synapse

Immunity (Cambridge, Mass.), 2002-04, Vol.16 (4), p.521-534

2002

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A Pivotal Role for the Multifunctional Calcium/Calmodulin-Dependent Protein Kinase II in T Cells: From Activation to Unresponsiveness

The Journal of immunology (1950), 2005-05, Vol.174 (9), p.5583-5592

2005

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Using live FRET imaging to reveal early protein–protein interactions during T cell activation

Current opinion in immunology, 2004-08, Vol.16 (4), p.418-427

2004

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The T cell receptor's alpha-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation

The Journal of immunology (1950), 2008-06, Vol.180 (12), p.8211-8221

2008

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A THEMIS : SHP 1 complex promotes T‐cell survival

The EMBO journal, 2015-02, Vol.34 (3), p.393-409

2015

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Molecular interactions at the T cell–antigen-presenting cell interface

Current opinion in immunology, 2004-02, Vol.16 (1), p.114-119

2004

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THEMIS: a critical TCR signal regulator for ligand discrimination

Costimulatory Molecule DNAM-1 Is Essential for Optimal Differentiation of Memory Natural Killer Cells during Mouse Cytomegalovirus Infection

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

Fine-tuning T cell receptor signaling to control T cell development

Signaling in thymic selection

A THEMIS:SHP1 complex promotes T-cell survival

A tryptophan metabolite made by a gut microbiome eukaryote induces pro‐inflammatory T cells

GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development

T Cell Receptor (TCR)-induced Tyrosine Phosphorylation Dynamics Identifies THEMIS as a New TCR Signalosome Component

SHP1‐ing thymic selection

Altered Peptide Ligands Induce Delayed CD8-T Cell Receptor Interaction—a Role for CD8 in Distinguishing Antigen Quality

The Lupus-Related Lmb3 Locus Contains a Disease-Suppressing Coronin-1A Gene Mutation

Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC

Molecular engineering of a therapeutic antibody for Blo t 5–induced allergic asthma

Themis controls T cell activation, effector functions, and metabolism of peripheral CD8 + T cells

T Cell Receptor Structures: Three for the Price of One

T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state

Hybrid structural modeling of alloantibody binding to human leukocyte antigen with rapid and reproducible cross-linking mass spectrometry

Opinion: Do T cells need endogenous peptides for activation?

Inhibition of T Cell Receptor-Coreceptor Interactions by Antagonist Ligands Visualized by Live FRET Imaging of the T-Hybridoma Immunological Synapse

A Pivotal Role for the Multifunctional Calcium/Calmodulin-Dependent Protein Kinase II in T Cells: From Activation to Unresponsiveness

Using live FRET imaging to reveal early protein–protein interactions during T cell activation

The T cell receptor's alpha-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation

A THEMIS : SHP 1 complex promotes T‐cell survival

Molecular interactions at the T cell–antigen-presenting cell interface

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