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The mammalian ULK1 complex and autophagy initiation

Essays in biochemistry, 2017-12, Vol.61 (6), p.585-596

2017

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Outstanding Questions in Mitophagy: What We Do and Do Not Know

Journal of molecular biology, 2020-01, Vol.432 (1), p.206-230

2020

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Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest

Molecular cell, 2011-06, Vol.42 (6), p.731-743

2011

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Strengthening the link between mitophagy and Parkinson's disease

Brain (London, England : 1878), 2022-12, Vol.145 (12), p.4154-4156

Ganley, Ian G

2022

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Parkinson's disease and mitophagy: an emerging role for LRRK2

Biochemical Society transactions, 2021-04, Vol.49 (2), p.551-562

2021

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Mammalian mitophagy – from in vitro molecules to in vivo models

The FEBS journal, 2018-04, Vol.285 (7), p.1185-1202

2018

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MTOR, PIK3C3, and autophagy: Signaling the beginning from the end

Autophagy, 2015-12, Vol.11 (12), p.2375-2376

2015

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The ULK1 complex: Sensing nutrient signals for autophagy activation

Autophagy, 2013-02, Vol.9 (2), p.124-137

2013

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Loss of iron triggers PINK1/Parkin-independent mitophagy

EMBO reports, 2013-12, Vol.14 (12), p.1127-1135

2013

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Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys

Autophagy, 2019-12, Vol.15 (12), p.2142-2162

2019

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mito-QC illuminates mitophagy and mitochondrial architecture in vivo

The Journal of cell biology, 2016-08, Vol.214 (3), p.333-345

2016

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ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

The Journal of biological chemistry, 2009-05, Vol.284 (18), p.12297-12305

2009

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Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling

PloS one, 2006-12, Vol.1 (1), p.e19-e19

2006

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Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy

The Journal of biological chemistry, 2015-05, Vol.290 (18), p.11376-11383

2015

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Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy

Current biology, 2018-08, Vol.28 (15), p.R842-R845

Ganley, Ian G.

2018

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Proinflammatory NFkB signalling promotes mitochondrial dysfunction in skeletal muscle in response to cellular fuel overloading

Cellular and molecular life sciences : CMLS, 2019-12, Vol.76 (24), p.4887-4904

2019

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Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

Biochemical journal, 2014-11, Vol.463 (3), p.413-427

2014

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Diversity of mitophagy pathways at a glance

Journal of cell science, 2022-12, Vol.135 (23)

2022

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Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

Cell metabolism, 2018-02, Vol.27 (2), p.439-449.e5

2018

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Semi-automated quantitation of mitophagy in cells and tissues

Mechanisms of ageing and development, 2020-01, Vol.185, p.111196-111196, Article 111196

2020

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Eating your mitochondria—when too much of a good thing turns bad

The EMBO journal, 2023-07, Vol.42 (13), p.e114542-n/a

2023

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Pharmacological rescue of impaired mitophagy in Parkinson's disease-related LRRK2 G2019S knock-in mice

eLife, 2021-08, Vol.10

2021

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The influence of aerobic exercise on mitochondrial quality control in skeletal muscle

The Journal of physiology, 2021-07, Vol.599 (14), p.3463-3476

2021

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Mitochondria and peroxisomes: partners in autophagy

Autophagy, 2023-07, Vol.19 (7), p.2162-2163

2023

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Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2

Journal of the American Chemical Society, 2022-09, Vol.144 (37), p.16930-16952

2022

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The mammalian ULK1 complex and autophagy initiation

Outstanding Questions in Mitophagy: What We Do and Do Not Know

Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest

Strengthening the link between mitophagy and Parkinson's disease

Parkinson's disease and mitophagy: an emerging role for LRRK2

Mammalian mitophagy – from in vitro molecules to in vivo models

MTOR, PIK3C3, and autophagy: Signaling the beginning from the end

The ULK1 complex: Sensing nutrient signals for autophagy activation

Loss of iron triggers PINK1/Parkin-independent mitophagy

Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys

mito-QC illuminates mitophagy and mitochondrial architecture in vivo

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling

Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy

Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy

Proinflammatory NFkB signalling promotes mitochondrial dysfunction in skeletal muscle in response to cellular fuel overloading

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

Diversity of mitophagy pathways at a glance

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

Semi-automated quantitation of mitophagy in cells and tissues

Eating your mitochondria—when too much of a good thing turns bad

Pharmacological rescue of impaired mitophagy in Parkinson's disease-related LRRK2 G2019S knock-in mice

The influence of aerobic exercise on mitochondrial quality control in skeletal muscle

Mitochondria and peroxisomes: partners in autophagy

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2

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