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Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease

Molecular psychiatry, 2006-08, Vol.11 (8), p.721-736

2006

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The role of beta amyloid in Alzheimer’s disease: still a cause of everything or the only one who got caught?

Pharmacological research, 2004-10, Vol.50 (4), p.397-409

2004

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The effect of APOE genotype on brain levels of oxysterols in young and old human APOE ε2, ε3 and ε4 knock-in mice

Neuroscience, 2010-08, Vol.169 (1), p.109-115

2010

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Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

Neuron (Cambridge, Mass.), 1996-07, Vol.17 (1), p.181-190

1996

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The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry

The Journal of biological chemistry, 1996-12, Vol.271 (50), p.31894-31902

1996

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Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins

The Journal of biological chemistry, 2002-08, Vol.277 (31), p.28135-28142

2002

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Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein

The Journal of neuroscience, 1994-05, Vol.14 (5), p.3122-3138

1994

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Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein

The Journal of biological chemistry, 1994-05, Vol.269 (18), p.13065-13068

1994

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Protein Topology of Presenilin 1

Neuron (Cambridge, Mass.), 1996-11, Vol.17 (5), p.1023-1030

1996

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Familial Alzheimer's disease-linked presenilin 1 variants elevate A beta 1-42/1-40 ratio in vitro and in vivo

Neuron (Cambridge, Mass.), 1996-11, Vol.17 (5), p.1005-1013

1996

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Expression of Presenilin 1 and 2 (PS1 and PS2) in Human and Murine Tissues

The Journal of neuroscience, 1996-12, Vol.16 (23), p.7513-7525

1996

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Cholinergic Agonists and Interleukin 1 Regulate Processing and Secretion of the Alzheimer β/A4 Amyloid Protein Precursor

Proceedings of the National Academy of Sciences - PNAS, 1992-11, Vol.89 (21), p.10075-10078

1992

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Relative Abundance of Alzheimer Aβ Amyloid Peptide Variants in Alzheimer Disease and Normal Aging

Proceedings of the National Academy of Sciences - PNAS, 1994-08, Vol.91 (18), p.8378-8382

1994

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Co‐expressed presenilin 1 NTF and CTF form functional γ‐secretase complexes in cells devoid of full‐length protein

Journal of neurochemistry, 2004-04, Vol.89 (1), p.44-53

2004

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Association of interleukin-1 polymorphisms with Alzheimer's disease in Australia

Annals of neurology, 2002-06, Vol.51 (6), p.795-797

2002

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Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer’s disease: no relation to apolipoprotein E expression or genotype

Biological psychiatry (1969), 2003-07, Vol.54 (2), p.136-141

2003

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Protein Phosphorylation Regulates Secretion of Alzheimer β/A4 Amyloid Precursor Protein

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (7), p.3055-3059

1992

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Apolipoprotein E promotes the binding and uptake of β-amyloid into Chinese hamster ovary cells in an isoform-specific manner

Neuroscience, 1999-01, Vol.90 (4), p.1217-1226

1999

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The effect of APOE genotype on brain levels of oxysterols in young and old human APOE Ik2, Ik3 and Ik4 knock-in mice

Neuroscience, 2010-08, Vol.169 (1), p.109-115

2010

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Increased plasma apolipoprotein E (apoE) levels in Alzheimer's disease

Neuroscience letters, 1997-02, Vol.223 (1), p.29-32

1997

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Identification of the Alzheimer beta/A4 amyloid precursor protein in clathrin-coated vesicles purified from PC12 cells

The Journal of biological chemistry, 1993-01, Vol.268 (1), p.608-612

1993

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Presenilin-1 Mutation L271V Results in Altered Exon 8 Splicing and Alzheimer's Disease with Non-cored Plaques and No Neuritic Dystrophy

The Journal of biological chemistry, 2003-02, Vol.278 (9), p.6748-6754

2003

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Alzheimer's disease amyloid-beta peptide modulates apolipoprotein E isoform specific receptor binding

Journal of Alzheimer's disease, 2005-08, Vol.7 (4), p.303-314

2005

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Characterization of stable complexes involving apolipoprotein E and the amyloid β peptide in Alzheimer's disease brain

Neuron (Cambridge, Mass.), 1995-07, Vol.15 (1), p.219-228

1995

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Two novel (M233T and ρ278T) presenilin-1 mutations in early-onset Alzheimerʼs disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype

Neuroreport, 1997-04, Vol.8 (6), p.1537-1542

1997

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Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease

The role of beta amyloid in Alzheimer’s disease: still a cause of everything or the only one who got caught?

The effect of APOE genotype on brain levels of oxysterols in young and old human APOE ε2, ε3 and ε4 knock-in mice

Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry

Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins

Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein

Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein

Protein Topology of Presenilin 1

Familial Alzheimer's disease-linked presenilin 1 variants elevate A beta 1-42/1-40 ratio in vitro and in vivo

Expression of Presenilin 1 and 2 (PS1 and PS2) in Human and Murine Tissues

Cholinergic Agonists and Interleukin 1 Regulate Processing and Secretion of the Alzheimer β/A4 Amyloid Protein Precursor

Relative Abundance of Alzheimer Aβ Amyloid Peptide Variants in Alzheimer Disease and Normal Aging

Co‐expressed presenilin 1 NTF and CTF form functional γ‐secretase complexes in cells devoid of full‐length protein

Association of interleukin-1 polymorphisms with Alzheimer's disease in Australia

Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer’s disease: no relation to apolipoprotein E expression or genotype

Protein Phosphorylation Regulates Secretion of Alzheimer β/A4 Amyloid Precursor Protein

Apolipoprotein E promotes the binding and uptake of β-amyloid into Chinese hamster ovary cells in an isoform-specific manner

The effect of APOE genotype on brain levels of oxysterols in young and old human APOE Ik2, Ik3 and Ik4 knock-in mice

Increased plasma apolipoprotein E (apoE) levels in Alzheimer's disease

Identification of the Alzheimer beta/A4 amyloid precursor protein in clathrin-coated vesicles purified from PC12 cells

Presenilin-1 Mutation L271V Results in Altered Exon 8 Splicing and Alzheimer's Disease with Non-cored Plaques and No Neuritic Dystrophy

Alzheimer's disease amyloid-beta peptide modulates apolipoprotein E isoform specific receptor binding

Characterization of stable complexes involving apolipoprotein E and the amyloid β peptide in Alzheimer's disease brain

Two novel (M233T and ρ278T) presenilin-1 mutations in early-onset Alzheimerʼs disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype

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