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Past, current, and future: Application of image analysis in small molecule pharmaceutical development

Journal of pharmaceutical sciences, 2024-08

2024

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A control strategy for bioavailability enhancement by size reduction: Effect of micronization conditions on the bulk, surface and blending characteristics of an active pharmaceutical ingredient

Powder technology, 2014-05, Vol.258, p.222-233

2014

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Morphological distribution mapping: Utilisation of modelling to integrate particle size and shape distributions

International journal of pharmaceutics, 2023-03, Vol.635, p.122743-122743, Article 122743

2023

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Application of Image-Based Particle Size and Shape Characterization Systems in the Development of Small Molecule Pharmaceuticals

Journal of pharmaceutical sciences, 2015-05, Vol.104 (5), p.1563-1574

2015

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Determining the Impact of Roller Compaction Processing Conditions on Granulate and API Properties: Impact of Formulation API Load

AAPS PharmSciTech, 2024-01, Vol.25 (1), p.24-24, Article 24

2024

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A Proposal for an Alternative Approach to Particle Size Method Development During Early-Stage Small Molecule Pharmaceutical Development

Journal of pharmaceutical sciences, 2019-11, Vol.108 (11), p.3515-3520

2019

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Monitoring process induced attrition of drug substance particles within formulated blends

International journal of pharmaceutics, 2014-08, Vol.470 (1-2), p.77-87

2014

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Characterization of the Morphological Nature of Hollow Spray Dried Dispersion Particles Using X-ray Submicron-Computed Tomography

AAPS PharmSciTech, 2021-12, Vol.23 (1), p.40-40, Article 40

2021

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Surface energy analysis as a tool to probe the surface energy characteristics of micronized materials—A comparison with inverse gas chromatography

International journal of pharmaceutics, 2012-01, Vol.422 (1), p.238-244

2012

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Investigation into process-induced de-aggregation of cohesive micronised API particles

International journal of pharmaceutics, 2015-09, Vol.493 (1-2), p.341-346

2015

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Particle Property Characterization and Data Curation for Effective Powder Property Modeling in the Pharmaceutical Industry

AAPS PharmSciTech, 2022-10, Vol.23 (8), p.286-286, Article 286

2022

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Application of X-ray microtomography for the characterisation of hollow polymer-stabilised spray dried amorphous dispersion particles

International journal of pharmaceutics, 2016-08, Vol.510 (1), p.1-8

2016

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Determining the Impact of Roller Compaction Processing Conditions on Granule and API Properties

AAPS PharmSciTech, 2020-08, Vol.21 (6), p.218-218, Article 218

2020

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Alternative approach for defining the particle population requirements for static image analysis based particle characterization methods

Advanced powder technology : the international journal of the Society of Powder Technology, Japan, 2019-05, Vol.30 (5), p.920-929

2019

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Investigation into the impact of sub-populations of agglomerates on the particle size distribution and flow properties of conventional microcrystalline cellulose grades

Pharmaceutical development and technology, 2011-10, Vol.16 (5), p.542-548

2011

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Airway Management in a Patient with Wolf-Hirschhorn Syndrome

Case reports in pediatrics, 2016-01, Vol.2016, p.7070125-2

2016

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Crystalline silica and Lung cancer: A critical review of the occupational epidemiology literature of exposure-response studies testing this hypothesis

Critical reviews in toxicology, 2011-05, Vol.41 (5), p.404-465

Gamble, John F.

2011

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An evaluation of the risks of lung cancer and mesothelioma from exposure to amphibole cleavage fragments

Regulatory toxicology and pharmacology, 2008-10, Vol.52 (1), p.S154-S186

2008

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Effect of crystal habits on the surface energy and cohesion of crystalline powders

International journal of pharmaceutics, 2014-09, Vol.472 (1-2), p.140-147

2014

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Enhanced Understanding of Pharmaceutical Materials Through Advanced Characterisation and Analysis

AAPS PharmSciTech, 2018-11, Vol.19 (8), p.3462-3480

2018

Volltextzugriff (PDF)

Application of imaging based tools for the characterisation of hollow spray dried amorphous dispersion particles

International journal of pharmaceutics, 2014-04, Vol.465 (1-2), p.210-217

2014

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The Secondary Drying and the Fate of Organic Solvents for Spray Dried Dispersion Drug Product

Pharmaceutical research, 2015-05, Vol.32 (5), p.1804-1816

2015

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Lung cancer and diesel exhaust: an updated critical review of the occupational epidemiology literature

Critical reviews in toxicology, 2012-08, Vol.42 (7), p.549-598

2012

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Determination of process variables affecting drug particle attrition withinmulti-component blends during powder feed transmission

Pharmaceutical development and technology, 2017-11, Vol.22 (7), p.904-909

2017

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Successful Ascending Aorta and Hemiarch Replacement and Aortic Valve Resuspension Via Redo Median Sternotomy Using Hypothermic Circulatory Arrest in a Practicing Jehovah's Witnesses Patient

Journal of cardiothoracic and vascular anesthesia, 2019-05, Vol.33 (5), p.1447-1454

2019

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Past, current, and future: Application of image analysis in small molecule pharmaceutical development

A control strategy for bioavailability enhancement by size reduction: Effect of micronization conditions on the bulk, surface and blending characteristics of an active pharmaceutical ingredient

Morphological distribution mapping: Utilisation of modelling to integrate particle size and shape distributions

Application of Image-Based Particle Size and Shape Characterization Systems in the Development of Small Molecule Pharmaceuticals

Determining the Impact of Roller Compaction Processing Conditions on Granulate and API Properties: Impact of Formulation API Load

A Proposal for an Alternative Approach to Particle Size Method Development During Early-Stage Small Molecule Pharmaceutical Development

Monitoring process induced attrition of drug substance particles within formulated blends

Characterization of the Morphological Nature of Hollow Spray Dried Dispersion Particles Using X-ray Submicron-Computed Tomography

Surface energy analysis as a tool to probe the surface energy characteristics of micronized materials—A comparison with inverse gas chromatography

Investigation into process-induced de-aggregation of cohesive micronised API particles

Particle Property Characterization and Data Curation for Effective Powder Property Modeling in the Pharmaceutical Industry

Application of X-ray microtomography for the characterisation of hollow polymer-stabilised spray dried amorphous dispersion particles

Determining the Impact of Roller Compaction Processing Conditions on Granule and API Properties

Alternative approach for defining the particle population requirements for static image analysis based particle characterization methods

Investigation into the impact of sub-populations of agglomerates on the particle size distribution and flow properties of conventional microcrystalline cellulose grades

Airway Management in a Patient with Wolf-Hirschhorn Syndrome

Crystalline silica and Lung cancer: A critical review of the occupational epidemiology literature of exposure-response studies testing this hypothesis

An evaluation of the risks of lung cancer and mesothelioma from exposure to amphibole cleavage fragments

Effect of crystal habits on the surface energy and cohesion of crystalline powders

Enhanced Understanding of Pharmaceutical Materials Through Advanced Characterisation and Analysis

Application of imaging based tools for the characterisation of hollow spray dried amorphous dispersion particles

The Secondary Drying and the Fate of Organic Solvents for Spray Dried Dispersion Drug Product

Lung cancer and diesel exhaust: an updated critical review of the occupational epidemiology literature

Determination of process variables affecting drug particle attrition withinmulti-component blends during powder feed transmission

Successful Ascending Aorta and Hemiarch Replacement and Aortic Valve Resuspension Via Redo Median Sternotomy Using Hypothermic Circulatory Arrest in a Practicing Jehovah's Witnesses Patient

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