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The role of immunophilins in viral infection

Biochimica et biophysica acta, 2015-10, Vol.1850 (10), p.2103-2110

2015

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Acute antagonism in three-drug combinations for vaginal HIV prevention in humanized mice

Scientific reports, 2023-03, Vol.13 (1), p.4594-11, Article 4594

2023

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Cyclophilin inhibition as a strategy for the treatment of human disease

Frontiers in pharmacology, 2024-07, Vol.15, p.1417945

2024

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HCV core protein and virus assembly: what we know without structures

Immunologic research, 2014-10, Vol.60 (1), p.1-10

2014

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Astodrimer sodium nasal spray forms a barrier to SARS-CoV-2 in vitro and preserves normal mucociliary function in human nasal epithelium

Scientific reports, 2024-09, Vol.14 (1), p.21259-11, Article 21259

2024

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The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate

PloS one, 2019-02, Vol.14 (2), p.e0211746-e0211746

2019

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The combination of the NS5A and cyclophilin inhibitors results in an additive anti-HCV inhibition in humanized mice without development of resistance

PloS one, 2021-05, Vol.16 (5), p.e0251934-e0251934

2021

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Cyclophilin inhibitors: a novel class of promising host-targeting anti-HCV agents

Immunologic research, 2012-06, Vol.52 (3), p.200-210

Gallay, Philippe A.

2012

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Cyclophilin Inhibitors Remodel the Endoplasmic Reticulum of HCV-Infected Cells in a Unique Pattern Rendering Cells Impervious to a Reinfection

PloS one, 2016-07, Vol.11 (7), p.e0159511-e0159511

2016

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The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action

PloS one, 2015-08, Vol.10 (8), p.e0134707

2015

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Protective Effects of Astodrimer Sodium 1% Nasal Spray Formulation against SARS-CoV-2 Nasal Challenge in K18-hACE2 Mice

Viruses, 2021-08, Vol.13 (8), p.1656

2021

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Prevention of vaginal and rectal HIV transmission by antiretroviral combinations in humanized mice

PloS one, 2017-09, Vol.12 (9), p.e0184303-e0184303

2017

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Cyclophilin Inhibitors

Clinics in liver disease, 2009-08, Vol.13 (3), p.403-417

Gallay, Philippe A., PhD

2009

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The Cyclophilin Inhibitor SCY-635 Disrupts Hepatitis C Virus NS5A-Cyclophilin A Complexes

Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3888-3897

2012

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Fundamental aspects of long-acting tenofovir alafenamide delivery from subdermal implants for HIV prophylaxis

Scientific reports, 2022-05, Vol.12 (1), p.8224-25, Article 8224

2022

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Correlation between NS5A Dimerization and Hepatitis C Virus Replication

The Journal of biological chemistry, 2012-08, Vol.287 (36), p.30861-30873

2012

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Characterization of the Anti-HCV Activities of the New Cyclophilin Inhibitor STG-175

PloS one, 2016-04, Vol.11 (4), p.e0152036-e0152036

2016

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Host-targeting agents in the treatment of hepatitis C: A beginning and an end?

Antiviral research, 2013-11, Vol.100 (2), p.555-561

2013

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Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerases (PARPs), blocks in vitro replication of SARS-CoV-2 variants

PloS one, 2022-09, Vol.17 (9), p.e0272916-e0272916

2022

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virocidal amphipathic α-helical peptide that inhibits hepatitis C virus infection in vitro

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (8), p.3088-3093

2008

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The Combination of Alisporivir plus an NS5A Inhibitor Provides Additive to Synergistic Anti-Hepatitis C Virus Activity without Detectable Cross-Resistance

Antimicrobial agents and chemotherapy, 2014-06, Vol.58 (6), p.3327-3334

2014

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Cell-Free Human Immunodeficiency Virus Type 1 Transcytosis through Primary Genital Epithelial Cells

Journal of Virology, 2007-01, Vol.81 (1), p.395-405

2007

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Multispecies Evaluation of a Long-Acting Tenofovir Alafenamide Subdermal Implant for HIV Prophylaxis

Frontiers in pharmacology, 2020-11, Vol.11, p.569373

2020

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Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction

PloS one, 2019-12, Vol.14 (12), p.e0226651-e0226651

2019

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HCV core residues critical for infectivity are also involved in core-NS5A complex formation

PloS one, 2014-02, Vol.9 (2), p.e88866

2014

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The role of immunophilins in viral infection

Acute antagonism in three-drug combinations for vaginal HIV prevention in humanized mice

Cyclophilin inhibition as a strategy for the treatment of human disease

HCV core protein and virus assembly: what we know without structures

Astodrimer sodium nasal spray forms a barrier to SARS-CoV-2 in vitro and preserves normal mucociliary function in human nasal epithelium

The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate

The combination of the NS5A and cyclophilin inhibitors results in an additive anti-HCV inhibition in humanized mice without development of resistance

Cyclophilin inhibitors: a novel class of promising host-targeting anti-HCV agents

Cyclophilin Inhibitors Remodel the Endoplasmic Reticulum of HCV-Infected Cells in a Unique Pattern Rendering Cells Impervious to a Reinfection

The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action

Protective Effects of Astodrimer Sodium 1% Nasal Spray Formulation against SARS-CoV-2 Nasal Challenge in K18-hACE2 Mice

Prevention of vaginal and rectal HIV transmission by antiretroviral combinations in humanized mice

Cyclophilin Inhibitors

The Cyclophilin Inhibitor SCY-635 Disrupts Hepatitis C Virus NS5A-Cyclophilin A Complexes

Fundamental aspects of long-acting tenofovir alafenamide delivery from subdermal implants for HIV prophylaxis

Correlation between NS5A Dimerization and Hepatitis C Virus Replication

Characterization of the Anti-HCV Activities of the New Cyclophilin Inhibitor STG-175

Host-targeting agents in the treatment of hepatitis C: A beginning and an end?

Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerases (PARPs), blocks in vitro replication of SARS-CoV-2 variants

virocidal amphipathic α-helical peptide that inhibits hepatitis C virus infection in vitro

The Combination of Alisporivir plus an NS5A Inhibitor Provides Additive to Synergistic Anti-Hepatitis C Virus Activity without Detectable Cross-Resistance

Cell-Free Human Immunodeficiency Virus Type 1 Transcytosis through Primary Genital Epithelial Cells

Multispecies Evaluation of a Long-Acting Tenofovir Alafenamide Subdermal Implant for HIV Prophylaxis

Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction

HCV core residues critical for infectivity are also involved in core-NS5A complex formation

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