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The role of immunophilins in viral infection

Biochimica et biophysica acta, 2015-10, Vol.1850 (10), p.2103-2110

2015

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Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerases (PARPs), blocks in vitro replication of SARS-CoV-2 variants

PloS one, 2022-09, Vol.17 (9), p.e0272916-e0272916

2022

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The influence of the 'organizational factor' on compound quality in drug discovery

Nature reviews. Drug discovery, 2011-10, Vol.10 (10), p.749-765

2011

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Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction

PloS one, 2019-12, Vol.14 (12), p.e0226651-e0226651

2019

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Distribution of naturally -occurring NS5B resistance-associated substitutions in Egyptian patients with chronic Hepatitis C

PloS one, 2021-04, Vol.16 (4), p.e0249770-e0249770

2021

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Acute antagonism in three-drug combinations for vaginal HIV prevention in humanized mice

Scientific reports, 2023-03, Vol.13 (1), p.4594-4594, Article 4594

2023

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Editing of the human TRIM5 gene to introduce mutations with the potential to inhibit HIV-1

PloS one, 2018-01, Vol.13 (1), p.e0191709-e0191709

2018

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A novel simple assay system to quantify the percent HCV-RNA levels of NS5A Y93H mutant strains and Y93 wild-type strains relative to the total HCV-RNA levels to determine the indication for antiviral therapy with NS5A inhibitors

PloS one, 2014-11, Vol.9 (11), p.e112647-e112647

2014

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Cyclophilin A (CypA) interacts with NF-κB subunit, p65/RelA, and contributes to NF-κB activation signaling

PloS one, 2014-08, Vol.9 (8), p.e96211

2014

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HCV core protein and virus assembly: what we know without structures

Immunologic research, 2014-10, Vol.60 (1), p.1-10

2014

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Artemisinin analogues as potent inhibitors of in vitro hepatitis C virus replication

PloS one, 2013-12, Vol.8 (12), p.e81783-e81783

2013

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The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate

PloS one, 2019-02, Vol.14 (2), p.e0211746-e0211746

2019

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The combination of the NS5A and cyclophilin inhibitors results in an additive anti-HCV inhibition in humanized mice without development of resistance

PloS one, 2021-05, Vol.16 (5), p.e0251934-e0251934

2021

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Characterization of Peptidyl-Prolyl Cis-Trans Isomerase- and Calmodulin-Binding Activity of a Cytosolic Arabidopsis thaliana Cyclophilin AtCyp19-3

PloS one, 2015-08, Vol.10 (8), p.e0136692-e0136692

2015

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LC3B is not recruited along with the autophagy elongation complex (ATG5-12/16L1) at HCV replication site and is dispensable for viral replication

PloS one, 2018-10, Vol.13 (10), p.e0205189-e0205189

2018

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Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid

PloS one, 2017-08, Vol.12 (8), p.e0182298-e0182298

2017

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Cyclophilin inhibitors: a novel class of promising host-targeting anti-HCV agents

Immunologic research, 2012-06, Vol.52 (3), p.200-210

Gallay, Philippe A.

2012

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Evaluation of the fusion inhibitor P3 peptide as a potential microbicide to prevent HIV transmission in women

PloS one, 2018-04, Vol.13 (4), p.e0195744-e0195744

2018

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Cyclophilin Inhibitors Remodel the Endoplasmic Reticulum of HCV-Infected Cells in a Unique Pattern Rendering Cells Impervious to a Reinfection

PloS one, 2016-07, Vol.11 (7), p.e0159511-e0159511

2016

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Biophysical property and broad anti-HIV activity of albuvirtide, a 3-maleimimidopropionic acid-modified peptide fusion inhibitor

PloS one, 2012-03, Vol.7 (3), p.e32599-e32599

2012

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Profile of alisporivir and its potential in the treatment of hepatitis C

Drug design, development and therapy, 2013-01, Vol.7 (default), p.105-115

2013

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Cyclosporin A inhibits the influenza virus replication through cyclophilin A-dependent and -independent pathways

PloS one, 2012-05, Vol.7 (5), p.e37277-e37277

2012

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The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action

PloS one, 2015-08, Vol.10 (8), p.e0134707

2015

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The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function

PloS one, 2012-06, Vol.7 (6), p.e39163-e39163

2012

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Prevention of vaginal and rectal HIV transmission by antiretroviral combinations in humanized mice

PloS one, 2017-09, Vol.12 (9), p.e0184303-e0184303

2017

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The role of immunophilins in viral infection

Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerases (PARPs), blocks in vitro replication of SARS-CoV-2 variants

The influence of the 'organizational factor' on compound quality in drug discovery

Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction

Distribution of naturally -occurring NS5B resistance-associated substitutions in Egyptian patients with chronic Hepatitis C

Acute antagonism in three-drug combinations for vaginal HIV prevention in humanized mice

Editing of the human TRIM5 gene to introduce mutations with the potential to inhibit HIV-1

A novel simple assay system to quantify the percent HCV-RNA levels of NS5A Y93H mutant strains and Y93 wild-type strains relative to the total HCV-RNA levels to determine the indication for antiviral therapy with NS5A inhibitors

Cyclophilin A (CypA) interacts with NF-κB subunit, p65/RelA, and contributes to NF-κB activation signaling

HCV core protein and virus assembly: what we know without structures

Artemisinin analogues as potent inhibitors of in vitro hepatitis C virus replication

The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate

The combination of the NS5A and cyclophilin inhibitors results in an additive anti-HCV inhibition in humanized mice without development of resistance

Characterization of Peptidyl-Prolyl Cis-Trans Isomerase- and Calmodulin-Binding Activity of a Cytosolic Arabidopsis thaliana Cyclophilin AtCyp19-3

LC3B is not recruited along with the autophagy elongation complex (ATG5-12/16L1) at HCV replication site and is dispensable for viral replication

Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid

Cyclophilin inhibitors: a novel class of promising host-targeting anti-HCV agents

Evaluation of the fusion inhibitor P3 peptide as a potential microbicide to prevent HIV transmission in women

Cyclophilin Inhibitors Remodel the Endoplasmic Reticulum of HCV-Infected Cells in a Unique Pattern Rendering Cells Impervious to a Reinfection

Biophysical property and broad anti-HIV activity of albuvirtide, a 3-maleimimidopropionic acid-modified peptide fusion inhibitor

Profile of alisporivir and its potential in the treatment of hepatitis C

Cyclosporin A inhibits the influenza virus replication through cyclophilin A-dependent and -independent pathways

The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action

The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function

Prevention of vaginal and rectal HIV transmission by antiretroviral combinations in humanized mice

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