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RNAi factors are present and active in human cell nuclei

Cell reports (Cambridge), 2014-01, Vol.6 (1), p.211-221

2014

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Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading

Nature protocols, 2014-09, Vol.9 (9), p.2045-2060

2014

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Promoter RNA links transcriptional regulation of inflammatory pathway genes

Nucleic acids research, 2013-12, Vol.41 (22), p.10086-10109

2013

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Global mpox lineage discovery and rapid outbreak tracking with nanopore sequencing

Virology journal, 2023-05, Vol.20 (1), p.90-90, Article 90

2023

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Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells

RNA (Cambridge), 2016-07, Vol.22 (7), p.1085-1098

2016

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RNA biology of disease-associated microsatellite repeat expansions

Acta neuropathologica communications, 2017-08, Vol.5 (1), p.63-63, Article 63

2017

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Chimeric Guides Probe and Enhance Cas9 Biochemical Activity

Biochemistry (Easton), 2018-05, Vol.57 (21), p.3027-3031

2018

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Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles

Nature communications, 2021-11, Vol.12 (1), p.6591-6591, Article 6591

2021

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Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs

Nature biotechnology, 2009-05, Vol.27 (5), p.478-484

2009

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Efficient Cloning and Sequence Validation of Repetitive and High GC-Content Short Hairpin RNAs

Human gene therapy, 2022-08, Vol.33 (15-16), p.829-839

2022

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Stepping toward therapeutic CRISPR

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (51), p.15536-15537

2015

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Sequencing-guided design of genetically encoded small RNAs targeting CAG repeats for selective inhibition of mutant huntingtin

Molecular therapy. Nucleic acids, 2024-06, Vol.35 (2), p.102206-102206, Article 102206

2024

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Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini

Nature chemical biology, 2010-08, Vol.6 (8), p.621-629

2010

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Quadruplex-Flanking Stem Structures Modulate the Stability and Metal Ion Preferences of RNA Mimics of GFP

ACS chemical biology, 2016-09, Vol.11 (9), p.2398-2406

2016

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Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs

Biological chemistry, 2011-04, Vol.392 (4), p.315-325

2011

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Microprobes for Label-Free Detection of Short Tandem Repeats: An Insight into Alleviating Secondary Structure Effects

Analytical chemistry (Washington), 2023-09, Vol.95 (36), p.13528-13536

2023

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Revisiting T7 RNA polymerase transcription in vitro with the Broccoli RNA aptamer as a simplified real-time fluorescent reporter

The Journal of biological chemistry, 2021-01, Vol.296, p.100175-100175, Article 100175

2021

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Dimeric Structure for Archaeal Box C/D Small Ribonucleoproteins

Science (American Association for the Advancement of Science), 2009-09, Vol.325 (5946), p.1384-1387

2009

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High throughput nanopore sequencing of SARS-CoV-2 viral genomes from patient samples

Journal of biological methods, 2021-09, Vol.8 (4), p.1-e155

2021

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Signature amino acids enable the archaeal L7Ae box C/D RNP core protein to recognize and bind the K-loop RNA motif

RNA (Cambridge), 2010-01, Vol.16 (1), p.79-90

2010

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Small nucleic acids and the path to the clinic for anti-CRISPR

Biochemical pharmacology, 2021-07, Vol.189, p.114492-114492, Article 114492

2021

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Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity

Nucleic acids research, 2019-01, Vol.47 (2), p.546

2019

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Loading of Argonaute Protein with Small Duplex RNA in Cellular Extracts

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1421, p.53

Gagnon, Keith T

2016

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Label-free Electrochemical Detection of CGG Repeats on Inkjet Printable 2D Layers of MoS2

ACS applied materials & interfaces, 2020-11, Vol.12 (46), p.52156-52165

2020

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Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches

Biochemistry (Easton), 2016-03, Vol.55 (9), p.1283-1286

2016

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RNAi factors are present and active in human cell nuclei

Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading

Promoter RNA links transcriptional regulation of inflammatory pathway genes

Global mpox lineage discovery and rapid outbreak tracking with nanopore sequencing

Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells

RNA biology of disease-associated microsatellite repeat expansions

Chimeric Guides Probe and Enhance Cas9 Biochemical Activity

Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles

Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs

Efficient Cloning and Sequence Validation of Repetitive and High GC-Content Short Hairpin RNAs

Stepping toward therapeutic CRISPR

Sequencing-guided design of genetically encoded small RNAs targeting CAG repeats for selective inhibition of mutant huntingtin

Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini

Quadruplex-Flanking Stem Structures Modulate the Stability and Metal Ion Preferences of RNA Mimics of GFP

Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs

Microprobes for Label-Free Detection of Short Tandem Repeats: An Insight into Alleviating Secondary Structure Effects

Revisiting T7 RNA polymerase transcription in vitro with the Broccoli RNA aptamer as a simplified real-time fluorescent reporter

Dimeric Structure for Archaeal Box C/D Small Ribonucleoproteins

High throughput nanopore sequencing of SARS-CoV-2 viral genomes from patient samples

Signature amino acids enable the archaeal L7Ae box C/D RNP core protein to recognize and bind the K-loop RNA motif

Small nucleic acids and the path to the clinic for anti-CRISPR

Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity

Loading of Argonaute Protein with Small Duplex RNA in Cellular Extracts

Label-free Electrochemical Detection of CGG Repeats on Inkjet Printable 2D Layers of MoS2

Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches

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