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Contacts with Macrophages Promote an Aggressive Nanomechanical Phenotype of Circulating Tumor Cells in Prostate Cancer

Cancer research (Chicago, Ill.), 2021-08, Vol.81 (15), p.4110-4123

2021

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Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination

Nature communications, 2023-10, Vol.14 (1), p.6569-6569, Article 6569

2023

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Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer

Cancer research (Chicago, Ill.), 2020-04, Vol.80 (7), p.1551-1563

2020

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Interplay between Structure and Charge as a Key to Allosteric Modulation of Human 20S Proteasome by the Basic Fragment of HIV-1 Tat Protein

PloS one, 2015-11, Vol.10 (11), p.e0143038

2015

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Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat

PloS one, 2012-05, Vol.7 (5), p.e35890-e35890

2012

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Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy

Nature communications, 2023-04, Vol.14 (1), p.2367-16, Article 2367

2023

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EpCAM-Regulated Transcription Exerts Influences on Nanomechanical Properties of Endometrial Cancer Cells That Promote Epithelial-to-Mesenchymal Transition

Cancer research (Chicago, Ill.), 2016-11, Vol.76 (21), p.6171-6182

2016

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Ex vivo drug testing of patient-derived lung organoids to predict treatment responses for personalized medicine

Lung cancer (Amsterdam, Netherlands), 2024-04, Vol.190, p.107533, Article 107533

2024

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PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms

Cell reports (Cambridge), 2024-08, Vol.43 (8), p.114527, Article 114527

2024

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AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages

Cell reports (Cambridge), 2023-09, Vol.42 (9), p.113067-113067, Article 113067

2023

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Targeting S6K/NFκB/SQSTM1/Polθ signaling to suppress radiation resistance in prostate cancer

Cancer letters, 2024-08, Vol.597, p.217063, Article 217063

2024

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Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer

Cancer research (Chicago, Ill.), 2019-01, Vol.79 (1), p.196-208

2019

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Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease

Neurobiology of aging, 2013-10, Vol.34 (10), p.2352-2360

2013

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Pipecolic esters as minimized templates for proteasome inhibition

Organic & biomolecular chemistry, 2019-03, Vol.17 (10), p.2734-2746

2019

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A Role for the Proteasome Alpha2 Subunit N-Tail in Substrate Processing

Biomolecules (Basel, Switzerland), 2023-03, Vol.13 (3), p.480

2023

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The central unit within the 19S regulatory particle of the proteasome

Nature structural & molecular biology, 2008-06, Vol.15 (6), p.573-580

2008

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Targeting Protein-Protein Interactions in the Proteasome Super-Assemblies

Current topics in medicinal chemistry, 2015-07, Vol.15 (20), p.2056-2067

2015

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Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer

Endocrinology (Philadelphia), 2020-02, Vol.161 (2), p.1

2020

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The proteasome in health and disease

Current pharmaceutical design, 2013, Vol.19 (6), p.1010-1028

2013

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Nanomechanical biomarkers of single circulating tumor cells for detection of castration resistant prostate cancer

The Prostate, 2014-09, Vol.74 (13), p.1297-1307

2014

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Electronic Circular Dichroism Detects Conformational Changes Associated with Proteasome Gating Confirmed Using AFM Imaging

Biomolecules (Basel, Switzerland), 2023-04, Vol.13 (4), p.704

2023

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EGFR-Dependent Regulated Intramembrane Proteolysis of EpCAM-Response

Cancer research (Chicago, Ill.), 2017-04, Vol.77 (7), p.1777-1777

2017

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The Growth-Suppressive Function of the Polycomb Group Protein Polyhomeotic Is Mediated by Polymerization of Its Sterile Alpha Motif (SAM) Domain

The Journal of biological chemistry, 2012-03, Vol.287 (12), p.8702-8713

2012

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AFM Imaging Reveals Topographic Diversity of Wild Type and Z Variant Polymers of Human α1-Proteinase Inhibitor

PloS one, 2016-03, Vol.11 (3), p.e0151902-e0151902

2016

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TGF-β signal rewiring sustains epithelial-mesenchymal transition of circulating tumor cells in prostate cancer xenograft hosts

Oncotarget, 2016-11, Vol.7 (47), p.77124-77137

2016

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Contacts with Macrophages Promote an Aggressive Nanomechanical Phenotype of Circulating Tumor Cells in Prostate Cancer

Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination

Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer

Interplay between Structure and Charge as a Key to Allosteric Modulation of Human 20S Proteasome by the Basic Fragment of HIV-1 Tat Protein

Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat

Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy

EpCAM-Regulated Transcription Exerts Influences on Nanomechanical Properties of Endometrial Cancer Cells That Promote Epithelial-to-Mesenchymal Transition

Ex vivo drug testing of patient-derived lung organoids to predict treatment responses for personalized medicine

PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms

AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages

Targeting S6K/NFκB/SQSTM1/Polθ signaling to suppress radiation resistance in prostate cancer

Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer

Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease

Pipecolic esters as minimized templates for proteasome inhibition

A Role for the Proteasome Alpha2 Subunit N-Tail in Substrate Processing

The central unit within the 19S regulatory particle of the proteasome

Targeting Protein-Protein Interactions in the Proteasome Super-Assemblies

Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer

The proteasome in health and disease

Nanomechanical biomarkers of single circulating tumor cells for detection of castration resistant prostate cancer

Electronic Circular Dichroism Detects Conformational Changes Associated with Proteasome Gating Confirmed Using AFM Imaging

EGFR-Dependent Regulated Intramembrane Proteolysis of EpCAM-Response

The Growth-Suppressive Function of the Polycomb Group Protein Polyhomeotic Is Mediated by Polymerization of Its Sterile Alpha Motif (SAM) Domain

AFM Imaging Reveals Topographic Diversity of Wild Type and Z Variant Polymers of Human α1-Proteinase Inhibitor

TGF-β signal rewiring sustains epithelial-mesenchymal transition of circulating tumor cells in prostate cancer xenograft hosts

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