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Application of the Palladium-Catalyzed Borylation/Suzuki Coupling (BSC) Reaction to the Synthesis of Biologically Active Biaryl Lactams

Journal of organic chemistry, 2002-02, Vol.67 (4), p.1199-1207

2002

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The Chemistry and Biology of Rhazinilam and Analogues

Mini-reviews in organic chemistry, 2004-07, Vol.1 (3), p.333-341

2004

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Asymmetric Synthesis of an Axially Chiral Antimitotic Biaryl via an Atropo-Enantioselective Suzuki Cross-Coupling

Journal of organic chemistry, 2003-06, Vol.68 (12), p.4897-4905

2003

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Palladium-Catalyzed Borylation of Ortho-Substituted Phenyl Halides and Application to the One-Pot Synthesis of 2,2‘-Disubstituted Biphenyls

Journal of organic chemistry, 2000-12, Vol.65 (26), p.9268-9271

2000

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Synthesis and Biological Evaluation of Vinca Alkaloids and Phomopsin Hybrids

Journal of medicinal chemistry, 2009-01, Vol.52 (1), p.134-142

2009

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The Complex of a Bivalent Derivative of Galanthamine with Torpedo Acetylcholinesterase Displays Drastic Deformation of the Active-Site Gorge: Implications for Structure-Based Drug Design

Journal of the American Chemical Society, 2004-12, Vol.126 (47), p.15405-15411

2004

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Taxol and taxotere: discovery, chemistry, and structure-activity relationships

Accounts of chemical research, 1993-04, Vol.26 (4), p.160-167

1993

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High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design

Biochimie, 2012-05, Vol.94 (5), p.1172-1179

2012

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Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity

Bioorganic & medicinal chemistry, 2005-05, Vol.13 (10), p.3497-3511

2005

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New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation

Bioorganic & medicinal chemistry, 2005-06, Vol.13 (11), p.3853-3864

2005

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New Potent Acetylcholinesterase Inhibitors in the Tetracyclic Triterpene Series

Journal of medicinal chemistry, 2007-11, Vol.50 (22), p.5311-5323

2007

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Semisynthesis and Biological Evaluation of a Novel D-Seco Docetaxel Analogue

Organic letters, 2006-05, Vol.8 (11), p.2301-2304

2006

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Synthesis and biological evaluation of (3,4,5-trimethoxyphenyl)indol-3-ylmethane derivatives as potential antivascular agents

Bioorganic & medicinal chemistry, 2006-07, Vol.14 (13), p.4410-4426

2006

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Novel B-ring modified allocolchicinoids of the NCME series: Design, synthesis, antimicrotubule activity and cytotoxicity

Bioorganic & medicinal chemistry, 2003-04, Vol.11 (7), p.1269-1281

2003

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Novel C2–C3′ N-peptide linked macrocyclic taxoids. Part 2: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives

Bioorganic & medicinal chemistry, 2007, Vol.15 (1), p.563-574

2007

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Synthesis and biological evaluation of B-ring analogues of (−)-rhazinilam

Bioorganic & medicinal chemistry, 2006-04, Vol.14 (7), p.2314-2332

2006

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Synthesis and biological evaluation of a-Ring biaryl-carbamate analogues of rhazinilam

Bioorganic & medicinal chemistry, 2002-11, Vol.10 (11), p.3395-3400

2002

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Highly efficient, practical approach to natural taxol

Journal of the American Chemical Society, 1988-08, Vol.110 (17), p.5917-5919

1988

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Relationships between the structure of taxol analogs and their antimitotic activity

Journal of medicinal chemistry, 1991-03, Vol.34 (3), p.992-998

1991

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Synthesis of Novel Macrocyclic Docetaxel Analogues. Influence of Their Macrocyclic Ring Size on Tubulin Activity

Journal of medicinal chemistry, 2003-08, Vol.46 (17), p.3623-3630

2003

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Structure of human glycolate oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole

Acta crystallographica. Section F, Structural biology and crystallization communications, 2009-12, Vol.65 (12), p.1246-1253

2009

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Cytotoxicity of Rhamnosylanthraquinones and Rhamnosylanthrones from Rhamnus nepalensis

Journal of natural products (Washington, D.C.), 2001-09, Vol.64 (9), p.1162-1168

2001

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Novel C2–C3′ N-peptide linked macrocyclic taxoids. Part 1: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C3

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (21), p.4722-4726

2005

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Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a taxol analogue

Cancer research (Baltimore), 1991-09, Vol.51 (18), p.4845-4852

1991

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Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity

Journal of medicinal chemistry, 2004-11, Vol.47 (24), p.5937-5944

2004

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Application of the Palladium-Catalyzed Borylation/Suzuki Coupling (BSC) Reaction to the Synthesis of Biologically Active Biaryl Lactams

The Chemistry and Biology of Rhazinilam and Analogues

Asymmetric Synthesis of an Axially Chiral Antimitotic Biaryl via an Atropo-Enantioselective Suzuki Cross-Coupling

Palladium-Catalyzed Borylation of Ortho-Substituted Phenyl Halides and Application to the One-Pot Synthesis of 2,2‘-Disubstituted Biphenyls

Synthesis and Biological Evaluation of Vinca Alkaloids and Phomopsin Hybrids

The Complex of a Bivalent Derivative of Galanthamine with Torpedo Acetylcholinesterase Displays Drastic Deformation of the Active-Site Gorge: Implications for Structure-Based Drug Design

Taxol and taxotere: discovery, chemistry, and structure-activity relationships

High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design

Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity

New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation

New Potent Acetylcholinesterase Inhibitors in the Tetracyclic Triterpene Series

Semisynthesis and Biological Evaluation of a Novel D-Seco Docetaxel Analogue

Synthesis and biological evaluation of (3,4,5-trimethoxyphenyl)indol-3-ylmethane derivatives as potential antivascular agents

Novel B-ring modified allocolchicinoids of the NCME series: Design, synthesis, antimicrotubule activity and cytotoxicity

Novel C2–C3′ N-peptide linked macrocyclic taxoids. Part 2: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives

Synthesis and biological evaluation of B-ring analogues of (−)-rhazinilam

Synthesis and biological evaluation of a-Ring biaryl-carbamate analogues of rhazinilam

Highly efficient, practical approach to natural taxol

Relationships between the structure of taxol analogs and their antimitotic activity

Synthesis of Novel Macrocyclic Docetaxel Analogues. Influence of Their Macrocyclic Ring Size on Tubulin Activity

Structure of human glycolate oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole

Cytotoxicity of Rhamnosylanthraquinones and Rhamnosylanthrones from Rhamnus nepalensis

Novel C2–C3′ N-peptide linked macrocyclic taxoids. Part 1: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C3

Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a taxol analogue

Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity

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