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GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

Nature medicine, 2017-10, Vol.23 (10), p.1150-1157

2017

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Proteopathic tau seeding predicts tauopathy in vivo

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.E4376-E4385

2014

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Peripheral biomarkers of major depression and antidepressant treatment response: Current knowledge and future outlooks

Journal of affective disorders, 2018-06, Vol.233, p.3-14

2018

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Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid

Acta neuropathologica, 2017-05, Vol.133 (5), p.751-765

2017

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Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease

The Journal of neuroscience, 2012-11, Vol.32 (46), p.16129-16140

2012

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A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein–Receptor Complexes

Journal of the American Chemical Society, 2014-06, Vol.136 (23), p.8411-8417

2014

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Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury

The Journal of neuroscience, 2016-02, Vol.36 (5), p.1502-1515

2016

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A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model

Clinical and translational science, 2023-08, Vol.16 (8), p.1431-1444

2023

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Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats

PloS one, 2012-05, Vol.7 (5), p.e38170

2012

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Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology

Journal of visualized experiments, 2011-03 (49)

2011

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A Versatile Platform for Single- and Multiple-Unnatural Amino Acid Mutagenesis in Escherichia coli

Biochemistry (Easton), 2013-03, Vol.52 (10), p.1828-1837

2013

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Parkinson’s disease and multiple system atrophy have distinct α-synuclein seed characteristics

The Journal of biological chemistry, 2019-01, Vol.294 (3), p.1045-1058

2019

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Widespread tau seeding activity at early Braak stages

Acta neuropathologica, 2017-01, Vol.133 (1), p.91-100

2017

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Turn-On DNA Damage Sensors for the Direct Detection of 8-Oxoguanine and Photoproducts in Native DNA

Journal of the American Chemical Society, 2011-08, Vol.133 (32), p.12518-12527

2011

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Calcineurin and glial signaling: neuroinflammation and beyond

Journal of neuroinflammation, 2014-09, Vol.11 (1), p.158-158, Article 158

2014

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Site-Specific Detection of DNA Methylation Utilizing mCpG-SEER

Journal of the American Chemical Society, 2006-08, Vol.128 (30), p.9761-9765

2006

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Toward a General Approach for RNA-Templated Hierarchical Assembly of Split-Proteins

Journal of the American Chemical Society, 2010-08, Vol.132 (33), p.11692-11701

2010

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Evaluating the Global CpG Methylation Status of Native DNA Utilizing a Bipartite Split-Luciferase Sensor

Analytical chemistry (Washington), 2011-09, Vol.83 (18), p.7151-7157

2011

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Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

Molecular neurodegeneration, 2009-11, Vol.4 (1), p.46-46, Article 46

2009

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Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

The Journal of neuroscience, 2017-06, Vol.37 (25), p.6132-6148

2017

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Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures

Neuroscience letters, 2010-01, Vol.469 (3), p.365-369

2010

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Childhood maltreatment and impact on clinical features of major depression in adults

Psychiatry research, 2020-11, Vol.293, p.113412-113412, Article 113412

2020

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Dysfunctional adaptive immune response in adolescents and young adults with suicide behavior

Psychoneuroendocrinology, 2020-01, Vol.111, p.104487-104487, Article 104487

2020

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Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

The Journal of neuroscience, 2009-10, Vol.29 (41), p.12957-12969

2009

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Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry

Journal of visualized experiments, 2015-12 (106), p.e53205-e53205

2015

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GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

Proteopathic tau seeding predicts tauopathy in vivo

Peripheral biomarkers of major depression and antidepressant treatment response: Current knowledge and future outlooks

Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid

Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease

A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein–Receptor Complexes

Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury

A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model

Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats

Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology

A Versatile Platform for Single- and Multiple-Unnatural Amino Acid Mutagenesis in Escherichia coli

Parkinson’s disease and multiple system atrophy have distinct α-synuclein seed characteristics

Widespread tau seeding activity at early Braak stages

Turn-On DNA Damage Sensors for the Direct Detection of 8-Oxoguanine and Photoproducts in Native DNA

Calcineurin and glial signaling: neuroinflammation and beyond

Site-Specific Detection of DNA Methylation Utilizing mCpG-SEER

Toward a General Approach for RNA-Templated Hierarchical Assembly of Split-Proteins

Evaluating the Global CpG Methylation Status of Native DNA Utilizing a Bipartite Split-Luciferase Sensor

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures

Childhood maltreatment and impact on clinical features of major depression in adults

Dysfunctional adaptive immune response in adolescents and young adults with suicide behavior

Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry

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