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hPSC-derived organoids: models of human development and disease

Journal of molecular medicine (Berlin, Germany), 2021-04, Vol.99 (4), p.463-473

2021

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Cell signaling and transcription factors regulating cell fate during formation of the mouse blastocyst

Trends in genetics, 2015-07, Vol.31 (7), p.402-410

2015

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HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo

eLife, 2018-12, Vol.7

2018

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Culture conditions antagonize lineage-promoting signaling in the mouse blastocyst

Reproduction (Cambridge, England), 2020-07, Vol.160 (1), p.V5-V7

2020

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Correction to: hPSC-derived organoids: models of human development and disease

Journal of molecular medicine (Berlin, Germany), 2021-04, Vol.99 (4), p.475-475

2021

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Visualizing HIPPO Signaling Components in Mouse Early Embryonic Development

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1893, p.335

2019

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AttrActin’ Attention to Early Mouse Development

Cell, 2018-04, Vol.173 (3), p.544-545

2018

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TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage

Development (Cambridge), 2019, Vol.146 (17)

2019

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HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst

PLoS genetics, 2014-10, Vol.10 (10), p.e1004618-e1004618

2014

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Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (36)

2021

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Oct4 Cell-Autonomously Promotes Primitive Endoderm Development in the Mouse Blastocyst

Developmental cell, 2013-06, Vol.25 (6), p.610-622

2013

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R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development

Developmental cell, 2022-07, Vol.57 (13), p.1598-1614.e8

2022

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Maternal Cdx2 is dispensable for mouse development

Development (Cambridge), 2012-11, Vol.139 (21), p.3969-3972

2012

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Understanding Human Lung Development through In Vitro Model Systems

BioEssays, 2020-06, Vol.42 (6), p.e2000006-n/a

2020

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Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential prior to implantation in mouse

Development (Cambridge), 2024-05

2024

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The accessible chromatin landscape of the human genome

Nature (London), 2012-09, Vol.489 (7414), p.75-82

2012

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Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos

Science (American Association for the Advancement of Science), 2023-12, Vol.382 (6676), p.eadi5516-eadi5516

2023

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CRISPR editing validation, immunostaining and DNA sequencing of individual fixed bovine embryos

BioTechniques, 2018-11, Vol.65 (5), p.281-283

2018

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Stable iPSC-derived NKX2-1+ lung bud tip progenitor organoids give rise to airway and alveolar cell types

Development (Cambridge), 2022-10, Vol.149 (20)

2022

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Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential before implantation

Development (Cambridge), 2024-06, Vol.151 (11)

2024

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Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung

Journal of medicinal chemistry, 2024-05, Vol.67 (9), p.7470-7486

2024

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Type I interferon signaling induces a delayed antiproliferative response in respiratory epithelial cells during SARS-CoV-2 infection

Journal of virology, 2023-12, Vol.97 (12), p.e0127623-e0127623

2023

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Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung

Proceedings of the National Academy of Sciences - PNAS, 2023-06, Vol.120 (24), p.e2210113120

2023

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Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung

npj Regenerative medicine, 2023-09, Vol.8 (1), p.48-48, Article 48

2023

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hPSC-derived organoids: models of human development and disease

Cell signaling and transcription factors regulating cell fate during formation of the mouse blastocyst

HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo

Culture conditions antagonize lineage-promoting signaling in the mouse blastocyst

Correction to: hPSC-derived organoids: models of human development and disease

Visualizing HIPPO Signaling Components in Mouse Early Embryonic Development

AttrActin’ Attention to Early Mouse Development

TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage

HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst

Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19

Oct4 Cell-Autonomously Promotes Primitive Endoderm Development in the Mouse Blastocyst

R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development

Maternal Cdx2 is dispensable for mouse development

Understanding Human Lung Development through In Vitro Model Systems

Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential prior to implantation in mouse

The accessible chromatin landscape of the human genome

Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation

CRISPR editing validation, immunostaining and DNA sequencing of individual fixed bovine embryos

Stable iPSC-derived NKX2-1+ lung bud tip progenitor organoids give rise to airway and alveolar cell types

Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential before implantation

Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung

Type I interferon signaling induces a delayed antiproliferative response in respiratory epithelial cells during SARS-CoV-2 infection

Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung

Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung

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