UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 30

Sortiert nach

Drug target residence time: a misleading concept

Drug discovery today, 2018-01, Vol.23 (1), p.12-16

Folmer, Rutger H.A.

2018

Volltextzugriff (PDF)

Fragment screening to predict druggability (ligandability) and lead discovery success

Drug discovery today, 2011-04, Vol.16 (7), p.284-287

2011

Volltextzugriff (PDF)

Integrating biophysics with HTS-driven drug discovery projects

Drug discovery today, 2016-03, Vol.21 (3), p.491-498

Folmer, Rutger H.A.

2016

Volltextzugriff (PDF)

Bivalent Ligands for Protein Degradation in Drug Discovery

Computational and structural biotechnology journal, 2019-01, Vol.17, p.160-176

2019

Volltextzugriff (PDF)

Exploitation of structural and regulatory diversity in glutamate racemases

Nature, 2007-06, Vol.447 (7146), p.817-822

2007

Volltextzugriff (PDF)

Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.5912-5925

2007

Volltextzugriff (PDF)

Discovery of a Novel Warhead against β-Secretase through Fragment-Based Lead Generation

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.5903-5911

2007

Volltextzugriff (PDF)

An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes

Current topics in medicinal chemistry, 2007-08, Vol.7 (16), p.1600

2007

Volltextzugriff (PDF)

Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design

Journal of medicinal chemistry, 2008-04, Vol.51 (7), p.2178-2186

2008

Volltextzugriff (PDF)

IMI European Lead Factory - democratizing access to high-throughput screening

Nature reviews. Drug discovery, 2022-04, Vol.21 (4), p.245-246

2022

Volltextzugriff (PDF)

Crystal Structure and NMR Studies of the Apo SH2 Domains of ZAP-70: Two Bikes Rather than a Tandem

Biochemistry (Easton), 2002-12, Vol.41 (48), p.14176-14184

2002

Volltextzugriff (PDF)

Unified Software Solution for Efficient SPR Data Analysis in Drug Research

SLAS discovery, 2017-02, Vol.22 (2), p.203-209

2017

Volltextzugriff (PDF)

Floating stereospecific assignment revisited: application to an 18 kDa protein and comparison with J-coupling data

Journal of biomolecular NMR, 1997-04, Vol.9 (3), p.245-258

1997

Volltextzugriff (PDF)

Interaction of the replication terminator protein of Bacillus subtilis with DNA probed by NMR spectroscopy

Biochemical and biophysical research communications, 2005-09, Vol.335 (2), p.361-366

2005

Volltextzugriff (PDF)

Structure of the PPARα and -γ Ligand Binding Domain in Complex with AZ 242; Ligand Selectivity and Agonist Activation in the PPAR Family

Structure (London), 2001-08, Vol.9 (8), p.699-706

2001

Volltextzugriff (PDF)

Refined Structure, DNA Binding Studies, and Dynamics of the Bacteriophage Pf3 Encoded Single-Stranded DNA Binding Protein

Biochemistry (Easton), 1997-07, Vol.36 (30), p.9120-9135

1997

Volltextzugriff (PDF)

Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats

Bioorganic & medicinal chemistry, 2011-05, Vol.19 (10), p.3039-3053

2011

Volltextzugriff (PDF)

Single-stranded DNA binding protein encoded by the filamentous bacteriophage M13: structural and functional characteristics

Molecular biology reports, 1995-01, Vol.20 (3), p.109-127

1995

Volltextzugriff (PDF)

Solution structure of the M13 major coat protein in detergent micelles: a basis for a model of phage assembly involving specific residues

Journal of molecular biology, 1998-09, Vol.282 (2), p.401-419

1998

Volltextzugriff (PDF)

Refined solution structure of the Tyr41-->His mutant of the M13 gene V protein. A comparison with the crystal structure

European journal of biochemistry, 1995-09, Vol.232 (2), p.506-514

1995

Volltextzugriff (PDF)

Secondary Structure of the Single‐stranded DNA Binding Protein Encoded by Filamentous Phage Pf3 as Determined by NMR

European journal of biochemistry, 1994-09, Vol.224 (2), p.663-676

1994

Volltextzugriff (PDF)

Sensitivity enhancement in (HCA)CONH experiments

Journal of biomolecular NMR, 2000-03, Vol.16 (3), p.229-233

2000

Volltextzugriff (PDF)

A (13)C double-filtered NOESY with strongly reduced artefacts and improved sensitivity

Journal of biomolecular NMR, 1995-06, Vol.5 (4), p.427-432

1995

Volltextzugriff (PDF)

J-Multiplied HSQC (MJ-HSQC): A New Method for Measuring3J(HNHα) Couplings in15N-labeled Proteins

Journal of magnetic resonance (1997), 1999-03, Vol.137 (1), p.243-246

1999

Volltextzugriff (PDF)

Three-dimensional structure of the single-stranded DNA-binding protein encoded by gene V of the filamentous bacteriophage M13 and a model of its complex with single-stranded DNA

FEMS microbiology reviews, 1995, Vol.17 (1), p.57-72

1995

Volltextzugriff (PDF)

1 – 25 von 30

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(28)
Mit Volltextzugriff
(24)

Publikationsform

Artikel
(28)
Tagungsberichte
(2)

Sprache

Englisch
(30)
Japanisch
(2)

Erscheinungsjahr

n.n

Menü

Weitere Dienste

Einstellungen

Drug target residence time: a misleading concept

Fragment screening to predict druggability (ligandability) and lead discovery success

Integrating biophysics with HTS-driven drug discovery projects

Bivalent Ligands for Protein Degradation in Drug Discovery

Exploitation of structural and regulatory diversity in glutamate racemases

Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Discovery of a Novel Warhead against β-Secretase through Fragment-Based Lead Generation

An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes

Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design

IMI European Lead Factory - democratizing access to high-throughput screening

Crystal Structure and NMR Studies of the Apo SH2 Domains of ZAP-70: Two Bikes Rather than a Tandem

Unified Software Solution for Efficient SPR Data Analysis in Drug Research

Floating stereospecific assignment revisited: application to an 18 kDa protein and comparison with J-coupling data

Interaction of the replication terminator protein of Bacillus subtilis with DNA probed by NMR spectroscopy

Structure of the PPARα and -γ Ligand Binding Domain in Complex with AZ 242; Ligand Selectivity and Agonist Activation in the PPAR Family

Refined Structure, DNA Binding Studies, and Dynamics of the Bacteriophage Pf3 Encoded Single-Stranded DNA Binding Protein

Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats

Single-stranded DNA binding protein encoded by the filamentous bacteriophage M13: structural and functional characteristics

Solution structure of the M13 major coat protein in detergent micelles: a basis for a model of phage assembly involving specific residues

Refined solution structure of the Tyr41-->His mutant of the M13 gene V protein. A comparison with the crystal structure

Secondary Structure of the Single‐stranded DNA Binding Protein Encoded by Filamentous Phage Pf3 as Determined by NMR

Sensitivity enhancement in (HCA)CONH experiments

A (13)C double-filtered NOESY with strongly reduced artefacts and improved sensitivity

J-Multiplied HSQC (MJ-HSQC): A New Method for Measuring3J(HNHα) Couplings in15N-labeled Proteins

Three-dimensional structure of the single-stranded DNA-binding protein encoded by gene V of the filamentous bacteriophage M13 and a model of its complex with single-stranded DNA

Suchergebnisse filtern