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Exploring the landscape of synthetic IL-6-type cytokines

The FEBS journal, 2024-05, Vol.291 (10), p.2030-2050

2024

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IL‐6 Trans‐signaling Controls Liver Regeneration After Partial Hepatectomy

Hepatology (Baltimore, Md.), 2019-12, Vol.70 (6), p.2075-2091

2019

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Synthetic cytokine receptors transmit biological signals using artificial ligands

Nature communications, 2018-05, Vol.9 (1), p.2034-15, Article 2034

2018

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Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

The Journal of biological chemistry, 2011-04, Vol.286 (17), p.14804-14811

2011

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IL-12 and IL-23—Close Relatives with Structural Homologies but Distinct Immunological Functions

Cells (Basel, Switzerland), 2020-09, Vol.9 (10), p.2184

2020

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CD73‐derived adenosine and tenascin‐C control cytokine production by epicardium‐derived cells formed after myocardial infarction

The FASEB journal, 2017-07, Vol.31 (7), p.3040-3053

2017

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Transcytosis of IL-11 and Apical Redirection of gp130 Is Mediated by IL-11α Receptor

Cell reports (Cambridge), 2016-07, Vol.16 (4), p.1067-1081

2016

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Transgenic Production of an Anti HIV Antibody in the Barley Endosperm

PloS one, 2015-10, Vol.10 (10), p.e0140476-e0140476

2015

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Human and Murine Interleukin 23 Receptors Are Novel Substrates for A Disintegrin and Metalloproteases ADAM10 and ADAM17

The Journal of biological chemistry, 2016-05, Vol.291 (20), p.10551-10561

2016

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Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling

Frontiers in microbiology, 2022-09, Vol.13, p.947169-947169

2022

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CoCl2‐triggered pseudohypoxic stress induces proteasomal degradation of SIRT4 via polyubiquitination of lysines K78 and K299

FEBS open bio, 2023-12, Vol.13 (12), p.2187-2199

2023

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ELPylated anti-human TNF therapeutic single-domain antibodies for prevention of lethal septic shock

Plant biotechnology journal, 2011-01, Vol.9 (1), p.22-31

2011

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Insights into IL-23 biology: From structure to function

Cytokine & growth factor reviews, 2015-10, Vol.26 (5), p.569-578

2015

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Veterinary vaccines from transgenic plants: highlights of two decades of research and a promising example

Current pharmaceutical design, 2013-09, Vol.19 (31), p.5601

2013

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Biochemical and functional characterization of anti-HIV antibody-ELP fusion proteins from transgenic plants

Plant biotechnology journal, 2008-05, Vol.6 (4), p.379-391

2008

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Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes

Communications biology, 2023-04, Vol.6 (1), p.418-418, Article 418

2023

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Naturally occurring and synthetic constitutive-active cytokine receptors in disease and therapy

Cytokine & growth factor reviews, 2019-06, Vol.47, p.1-20

2019

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Immunoreceptor Engineering and Synthetic Cytokine Signaling for Therapeutics

Trends in immunology, 2019-03, Vol.40 (3), p.258-272

2019

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Synthetic receptor platform to identify loss-of-function single nucleotide variants and designed mutants in the death receptor Fas/CD95

The Journal of biological chemistry, 2023-08, Vol.299 (8), p.104989-104989, Article 104989

2023

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Current status and relevance of single nucleotide polymorphisms in IL-6-/IL-12-type cytokine receptors

Cytokine (Philadelphia, Pa.), 2021-12, Vol.148, p.155550-155550, Article 155550

2021

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Elastin-like polypeptides revolutionize recombinant protein expression and their biomedical application

Trends in biotechnology (Regular ed.), 2010-01, Vol.28 (1), p.37-45

2010

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Covalent dimerization of camelidae anti-human TNF-alpha single domain antibodies by the constant kappa light chain domain improves neutralizing activity

Biotechnology and bioengineering, 2010-05, Vol.106 (1), p.161-166

2010

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Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR

The Journal of biological chemistry, 2024-04, Vol.300 (5), p.107251-107251, Article 107251

2024

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Bispecific soluble cytokine receptor-nanobody fusions inhibit Interleukin (IL-)6 trans-signaling and IL-12/23 or tumor necrosis factor (TNF) signaling

The Journal of biological chemistry, 2023-11, Vol.299 (11), p.105343-105343, Article 105343

2023

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Respiratory syncytial virus–approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors

The Journal of biological chemistry, 2023-11, Vol.299 (11), p.105270-105270, Article 105270

2023

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Exploring the landscape of synthetic IL-6-type cytokines

IL‐6 Trans‐signaling Controls Liver Regeneration After Partial Hepatectomy

Synthetic cytokine receptors transmit biological signals using artificial ligands

Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

IL-12 and IL-23—Close Relatives with Structural Homologies but Distinct Immunological Functions

CD73‐derived adenosine and tenascin‐C control cytokine production by epicardium‐derived cells formed after myocardial infarction

Transcytosis of IL-11 and Apical Redirection of gp130 Is Mediated by IL-11α Receptor

Transgenic Production of an Anti HIV Antibody in the Barley Endosperm

Human and Murine Interleukin 23 Receptors Are Novel Substrates for A Disintegrin and Metalloproteases ADAM10 and ADAM17

Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling

CoCl2‐triggered pseudohypoxic stress induces proteasomal degradation of SIRT4 via polyubiquitination of lysines K78 and K299

ELPylated anti-human TNF therapeutic single-domain antibodies for prevention of lethal septic shock

Insights into IL-23 biology: From structure to function

Veterinary vaccines from transgenic plants: highlights of two decades of research and a promising example

Biochemical and functional characterization of anti-HIV antibody-ELP fusion proteins from transgenic plants

Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes

Naturally occurring and synthetic constitutive-active cytokine receptors in disease and therapy

Immunoreceptor Engineering and Synthetic Cytokine Signaling for Therapeutics

Synthetic receptor platform to identify loss-of-function single nucleotide variants and designed mutants in the death receptor Fas/CD95

Current status and relevance of single nucleotide polymorphisms in IL-6-/IL-12-type cytokine receptors

Elastin-like polypeptides revolutionize recombinant protein expression and their biomedical application

Covalent dimerization of camelidae anti-human TNF-alpha single domain antibodies by the constant kappa light chain domain improves neutralizing activity

Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR

Bispecific soluble cytokine receptor-nanobody fusions inhibit Interleukin (IL-)6 trans-signaling and IL-12/23 or tumor necrosis factor (TNF) signaling

Respiratory syncytial virus–approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors

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