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Metabolomics signature as a survival predictor in patients with resectable colorectal liver metastasis

Clinical and translational medicine, 2024-01, Vol.14 (1), p.e1541-n/a

2024

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Preclinical Evaluation of an Imidazole-Linked Heterocycle for Alzheimer’s Disease

Pharmaceutics, 2023-09, Vol.15 (10), p.2381

2023

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Discovery of bioactive natural products of microbial origin as inhibitors of the PD-1/PD-L1 protein-protein interaction

International journal of biological macromolecules, 2024-04, Vol.264 (Pt 1), p.130458-130458, Article 130458

2024

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Isolation, culture and characterization of primary mouse RPE cells

Nature protocols, 2016-07, Vol.11 (7), p.1206-1218

2016

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Onychocolone A produced by the fungus Onychocola sp. targets cancer stem cells and stops pancreatic cancer progression by inhibiting MEK2-dependent cell signaling

Biomedicine & pharmacotherapy, 2024-08, Vol.177, p.117018, Article 117018

2024

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C3a triggers formation of sub-retinal pigment epithelium deposits via the ubiquitin proteasome pathway

Scientific reports, 2018-06, Vol.8 (1), p.9679-14, Article 9679

2018

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AMD-Like Substrate Causes Epithelial Mesenchymal Transition in iPSC-Derived Retinal Pigment Epithelial Cells Wild Type but Not C3-Knockout

International journal of molecular sciences, 2021-08, Vol.22 (15), p.8183

2021

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Changes in extracellular matrix cause RPE cells to make basal deposits and activate the alternative complement pathway

Human molecular genetics, 2018-01, Vol.27 (1), p.147-159

2018

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Effects of a New Combination of Natural Extracts on Glaucoma-Related Retinal Degeneration

Foods, 2021-08, Vol.10 (8), p.1885

2021

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Complement C5 is not critical for the formation of sub-RPE deposits in Efemp1 mutant mice

Scientific reports, 2021-05, Vol.11 (1), p.10416-10416, Article 10416

2021

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AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/− iPSC-Derived RPE Cells

Molecular therapy. Methods & clinical development, 2019-12, Vol.15, p.392-402

2019

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Repurposing the Open Global Health Library for the discovery of novel Mpro destabilizers with scope as broad-spectrum antivirals

Frontiers in pharmacology, 2024-07, Vol.15, p.1390705

2024

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Characterization of lincRNA expression in the human retinal pigment epithelium and differentiated induced pluripotent stem cells

PloS one, 2017-08, Vol.12 (8), p.e0183939-e0183939

2017

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Alterations in Extracellular Matrix/Bruch’s Membrane Can Cause the Activation of the Alternative Complement Pathway via Tick-Over

Advances in experimental medicine and biology, 2018, Vol.1074, p.29-35

2018

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Changes in extracellular matrix cause RPE cells to make basal deposits and activate the alternative complement pathway

Human molecular genetics, 2018-01, Vol.27 (1), p.147-159

2018

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Efficient Dissection and Culture of Primary Mouse Retinal Pigment Epithelial Cells

Journal of visualized experiments, 2021-02 (168)

2021

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A local complement response by RPE causes early-stage macular degeneration

Human molecular genetics, 2015-10, Vol.24 (19), p.5555-5569

2015

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Efficient Dissection and Culture of Primary Mouse Retinal Pigment Epithelial Cells

Journal of visualized experiments, 2021-02 (168)

2021

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Extracellular Matrix Alterations and Deposit Formation in AMD

Advances in experimental medicine and biology, 2016-01, Vol.854, p.53-58

2016

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The Role of Complement and the Extracellular Matrix in Early Stage Macular Degeneration

The FASEB journal, 2015-04, Vol.29 (S1)

2015

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Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration

Human molecular genetics, 2023-01, Vol.32 (2), p.204-217

2023

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Copy-number variation is an important contributor to the genetic causality of inherited retinal degenerations

Genetics in medicine, 2017-06, Vol.19 (6), p.643-651

2017

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Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration

Human molecular genetics, 2014-01, Vol.23 (1), p.52-68

2014

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International mentoring as a new educational approach to alleviate brain drain, empower young talent, and internationalize higher education

Nature biotechnology, 2017-03, Vol.35 (3), p.285-288

2017

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Retina
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Retinal Pigment Epithelium
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Cells, Cultured
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Epithelium
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Complement C3 - Metabolism
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Metabolomics signature as a survival predictor in patients with resectable colorectal liver metastasis

Preclinical Evaluation of an Imidazole-Linked Heterocycle for Alzheimer’s Disease

Discovery of bioactive natural products of microbial origin as inhibitors of the PD-1/PD-L1 protein-protein interaction

Isolation, culture and characterization of primary mouse RPE cells

Onychocolone A produced by the fungus Onychocola sp. targets cancer stem cells and stops pancreatic cancer progression by inhibiting MEK2-dependent cell signaling

C3a triggers formation of sub-retinal pigment epithelium deposits via the ubiquitin proteasome pathway

AMD-Like Substrate Causes Epithelial Mesenchymal Transition in iPSC-Derived Retinal Pigment Epithelial Cells Wild Type but Not C3-Knockout

Changes in extracellular matrix cause RPE cells to make basal deposits and activate the alternative complement pathway

Effects of a New Combination of Natural Extracts on Glaucoma-Related Retinal Degeneration

Complement C5 is not critical for the formation of sub-RPE deposits in Efemp1 mutant mice

AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/− iPSC-Derived RPE Cells

Repurposing the Open Global Health Library for the discovery of novel Mpro destabilizers with scope as broad-spectrum antivirals

Characterization of lincRNA expression in the human retinal pigment epithelium and differentiated induced pluripotent stem cells

Alterations in Extracellular Matrix/Bruch’s Membrane Can Cause the Activation of the Alternative Complement Pathway via Tick-Over

Changes in extracellular matrix cause RPE cells to make basal deposits and activate the alternative complement pathway

Efficient Dissection and Culture of Primary Mouse Retinal Pigment Epithelial Cells

A local complement response by RPE causes early-stage macular degeneration

Efficient Dissection and Culture of Primary Mouse Retinal Pigment Epithelial Cells

Extracellular Matrix Alterations and Deposit Formation in AMD

The Role of Complement and the Extracellular Matrix in Early Stage Macular Degeneration

Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration

Copy-number variation is an important contributor to the genetic causality of inherited retinal degenerations

Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration

International mentoring as a new educational approach to alleviate brain drain, empower young talent, and internationalize higher education

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