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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

PLoS medicine, 2020-03, Vol.17 (3), p.e1003062-e1003062

2020

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Effect of Naturally Random Allocation to Lower Low-Density Lipoprotein Cholesterol on the Risk of Coronary Heart Disease Mediated by Polymorphisms in NPC1L1 , HMGCR , or Both

Journal of the American College of Cardiology, 2015-04, Vol.65 (15), p.1552-1561

2015

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Mendelian Randomization Study of ACLY and Cardiovascular Disease

The New England journal of medicine, 2019-03, Vol.380 (11), p.1033-1042

2019

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How to use Mendelian randomization to anticipate the results of randomized trials

European heart journal, 2018-02, Vol.39 (5), p.360-362

Ference, Brian A

2018

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Impact of Lipids on Cardiovascular Health: JACC Health Promotion Series

Journal of the American College of Cardiology, 2018-09, Vol.72 (10), p.1141-1156

2018

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Interpreting the Clinical Implications of Drug-Target Mendelian Randomization Studies

Journal of the American College of Cardiology, 2022-08, Vol.80 (7), p.663-665

Ference, Brian A.

2022

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World Heart Federation Cholesterol Roadmap 2022

Global heart, 2022-10, Vol.17 (1), p.75-75

2022

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The Potential Clinical Benefit of Lowering Lipoprotein(a)

JAMA : the journal of the American Medical Association, 2022-05, Vol.327 (17), p.1653

Ference, Brian A

2022

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Mendelian randomization studies: using naturally randomized genetic data to fill evidence gaps

Current opinion in lipidology, 2015-12, Vol.26 (6), p.566-571

Ference, Brian A

2015

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The Role of Early LDL Lowering to Prevent the Onset of Atherosclerotic Disease

Current atherosclerosis reports, 2013-04, Vol.15 (4), p.312-312, Article 312

2013

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Using Mendelian Randomization to Improve the Design of Randomized Trials

Cold Spring Harbor perspectives in biology, 2021-07, Vol.11 (7), p.a040980

2021

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Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis

JAMA : the journal of the American Medical Association, 2016-09, Vol.316 (12), p.1289

2016

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Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study

Journal of the American College of Cardiology, 2015-04, Vol.65 (15), p.1552-1561

2015

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Using Genetic Variants in the Targets of Lipid Lowering Therapies to Inform Drug Discovery and Development: Current and Future Treatment Options

Clinical pharmacology and therapeutics, 2019-03, Vol.105 (3), p.568-581

Ference, Brian A.

2019

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Lipids and Lipoproteins in 2020

JAMA : the journal of the American Medical Association, 2020-08, Vol.324 (6), p.595

2020

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A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: two meta-analyses and a meta-regression analysis

PloS one, 2011-12, Vol.6 (12), p.e28834-e28834

2011

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Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review

JAMA cardiology, 2019-12, Vol.4 (12), p.1287

2019

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Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

The New England journal of medicine, 2016-12, Vol.375 (22), p.2144-2153

2016

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Causal Effect of Lipids and Lipoproteins on Atherosclerosis: Lessons from Genomic Studies

Cardiology clinics, 2018-05, Vol.36 (2), p.203-211

Ference, Brian A

2018

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Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease

JAMA : the journal of the American Medical Association, 2019-10, Vol.322 (14), p.1381

2019

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Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

European heart journal, 2022-10, Vol.43 (39), p.3925-3946

2022

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The LDL cumulative exposure hypothesis: evidence and practical applications

Nature reviews cardiology, 2024-10, Vol.21 (10), p.701

2024

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Association Between Triglyceride Lowering and Reduction of Cardiovascular Risk Across Multiple Lipid-Lowering Therapeutic Classes: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials

Circulation (New York, N.Y.), 2019-10, Vol.140 (16), p.1308-1317

2019

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Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease

JAMA : the journal of the American Medical Association, 2019-01, Vol.321 (4), p.364

2019

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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

Effect of Naturally Random Allocation to Lower Low-Density Lipoprotein Cholesterol on the Risk of Coronary Heart Disease Mediated by Polymorphisms in NPC1L1 , HMGCR , or Both

Mendelian Randomization Study of ACLY and Cardiovascular Disease

How to use Mendelian randomization to anticipate the results of randomized trials

Impact of Lipids on Cardiovascular Health: JACC Health Promotion Series

Interpreting the Clinical Implications of Drug-Target Mendelian Randomization Studies

World Heart Federation Cholesterol Roadmap 2022

The Potential Clinical Benefit of Lowering Lipoprotein(a)

Mendelian randomization studies: using naturally randomized genetic data to fill evidence gaps

The Role of Early LDL Lowering to Prevent the Onset of Atherosclerotic Disease

Using Mendelian Randomization to Improve the Design of Randomized Trials

Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis

Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study

Using Genetic Variants in the Targets of Lipid Lowering Therapies to Inform Drug Discovery and Development: Current and Future Treatment Options

Lipids and Lipoproteins in 2020

A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: two meta-analyses and a meta-regression analysis

Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review

Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes

Causal Effect of Lipids and Lipoproteins on Atherosclerosis: Lessons from Genomic Studies

Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease

Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society

The LDL cumulative exposure hypothesis: evidence and practical applications

Association Between Triglyceride Lowering and Reduction of Cardiovascular Risk Across Multiple Lipid-Lowering Therapeutic Classes: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials

Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease

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