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The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases

International journal of molecular sciences, 2020-01, Vol.21 (2), p.657

2020

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Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes

Frontiers in physiology, 2020-06, Vol.11, p.504-504

2020

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A novel ion conducting route besides the central pore in an inherited mutant of G‐protein‐gated inwardly rectifying K+ channel

The Journal of physiology, 2022-02, Vol.600 (3), p.603-622

2022

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Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277

Nature communications, 2022-06, Vol.13 (1), p.3760-3760, Article 3760

2022

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Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening

Nature communications, 2017-11, Vol.8 (1), p.1730-11, Article 1730

2017

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Single-channel basis for the slow activation of the repolarizing cardiac potassium current, IKs

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (11), p.E996-E1005

2013

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In Silico Evaluation of Hexamethylene Amiloride Derivatives as Potential Luminal Inhibitors of SARS-CoV-2 E Protein

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10647

2022

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Dynamic of ion channel expression at the plasma membrane of cardiomyocytes

Physiological reviews, 2012-07, Vol.92 (3), p.1317-1358

2012

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A structural interpretation of voltage-gated potassium channel inactivation

Progress in biophysics and molecular biology, 2006-10, Vol.92 (2), p.185-208

2006

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cAMP-dependent regulation of IKs single-channel kinetics

The Journal of general physiology, 2017-08, Vol.149 (8), p.781-798

2017

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The I Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry

Biophysical journal, 2018-11, Vol.115 (9), p.1731-1740

2018

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The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation

Cardiovascular research, 2013-04, Vol.98 (1), p.145-154

2013

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Modeling the Hidden Pathways of IKs Channel Activation

Biophysical journal, 2018-07, Vol.115 (1), p.1-2

Fedida, David

2018

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A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

eLife, 2023-09, Vol.12

2023

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KN-93 (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels

The Journal of pharmacology and experimental therapeutics, 2006-04, Vol.317 (1), p.292

2006

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The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome

Expert reviews in molecular medicine, 2011-12, Vol.13, p.e38-e38, Article e38

2011

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The Mechanism of Atrial Antiarrhythmic Action of RSD1235

Journal of cardiovascular electrophysiology, 2005-11, Vol.16 (11), p.1227-1238

2005

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Heterogeneous expression of repolarizing, voltage-gated K+ currents in adult mouse ventricles

The Journal of physiology, 2004-08, Vol.559 (1), p.103-120

2004

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Novel Acylguanidine-Based Inhibitor of HIV-1

Journal of virology, 2016-10, Vol.90 (20), p.9495-9508

2016

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Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors

PloS one, 2015-04, Vol.10 (4), p.e0121099-e0121099

2015

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Mechanisms of cardiac potassium channel trafficking

The Journal of physiology, 2007-07, Vol.582 (1), p.17-26

2007

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Dual Effect of Phosphatidyl (4,5)-Bisphosphate PIP2 on Shaker K+ Channels

The Journal of biological chemistry, 2012-10, Vol.287 (43), p.36158-36167

2012

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Vernakalant (RSD1235): a novel, atrial-selective antifibrillatory agent

Expert opinion on investigational drugs, 2007-04, Vol.16 (4), p.519-532

Fedida, David

2007

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Cholesterol modulates the recruitment of Kv1.5 channels from Rab11-associated recycling endosome in native atrial myocytes

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (34), p.14681-14686

2009

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De Novo Mutation in the SCN5A Gene Associated with Brugada Syndrome

Cellular physiology and biochemistry, 2015-08, Vol.36 (6), p.2250-2262

2015

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The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases

Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes

A novel ion conducting route besides the central pore in an inherited mutant of G‐protein‐gated inwardly rectifying K+ channel

Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277

Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening

Single-channel basis for the slow activation of the repolarizing cardiac potassium current, IKs

In Silico Evaluation of Hexamethylene Amiloride Derivatives as Potential Luminal Inhibitors of SARS-CoV-2 E Protein

Dynamic of ion channel expression at the plasma membrane of cardiomyocytes

A structural interpretation of voltage-gated potassium channel inactivation

cAMP-dependent regulation of IKs single-channel kinetics

The I Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry

The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation

Modeling the Hidden Pathways of IKs Channel Activation

A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

KN-93 (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels

The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome

The Mechanism of Atrial Antiarrhythmic Action of RSD1235

Heterogeneous expression of repolarizing, voltage-gated K+ currents in adult mouse ventricles

Novel Acylguanidine-Based Inhibitor of HIV-1

Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors

Mechanisms of cardiac potassium channel trafficking

Dual Effect of Phosphatidyl (4,5)-Bisphosphate PIP2 on Shaker K+ Channels

Vernakalant (RSD1235): a novel, atrial-selective antifibrillatory agent

Cholesterol modulates the recruitment of Kv1.5 channels from Rab11-associated recycling endosome in native atrial myocytes

De Novo Mutation in the SCN5A Gene Associated with Brugada Syndrome

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