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MutSignatures: an R package for extraction and analysis of cancer mutational signatures

Scientific reports, 2020-10, Vol.10 (1), p.18217-18217, Article 18217

2020

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Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment

Cellular and molecular life sciences : CMLS, 2010-11, Vol.67 (21), p.3589-3608

2010

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Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy

Nature medicine, 2018-06, Vol.24 (6), p.758-769

2018

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Identification of Differential Tumor Subtypes of T1 Bladder Cancer

European urology, 2020-10, Vol.78 (4), p.533-537

2020

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DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer

Cancer research (Chicago, Ill.), 2017-12, Vol.77 (23), p.6562-6575

2017

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APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

Molecular and Cellular Biology, 2009-04, Vol.29 (7), p.1834-1854

2009

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A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression

PLoS computational biology, 2023-04, Vol.19 (4), p.e1010995-e1010995

2023

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Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions

Nucleic acids research, 2010-12, Vol.38 (22), p.8239

2010

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DIscBIO: A User-Friendly Pipeline for Biomarker Discovery in Single-Cell Transcriptomics

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1399

2021

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The prion protein is critical for DNA repair and cell survival after genotoxic stress

Nucleic acids research, 2015-01, Vol.43 (2), p.904

2015

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Baricitinib-associated changes in global gene expression during a 24-week phase II clinical systemic lupus erythematosus trial implicates a mechanism of action through multiple immune-related pathways

Lupus science & medicine, 2020-10, Vol.7 (1), p.e000424

2020

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Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma

Oncoimmunology, 2020-01, Vol.9 (1), p.1744897

2020

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1056 XTX301, a tumor activated, half-life extended IL-12 promoted potent anti-tumor immunity and activity across multiple syngeneic tumor models

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1163-A1163

2023

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611 XTX202–01/02–001, Phase 1/2 first-in human study of XTX202, a masked, tumor-activated IL-2βγ, in patients with advanced solid tumors: results from phase 1

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A695-A696

2023

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Analysis of Mutational Signatures Using the mutSignatures R Library

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2684, p.45

2023

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Molecular footprints of muscle-invasive bladder cancer in smoking and nonsmoking patients

Urologic oncology, 2019-11, Vol.37 (11), p.818-825

2019

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Genomic classification and risk stratification of bladder cancer

World journal of urology, 2019-09, Vol.37 (9), p.1751-1757

2019

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A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer

Oncogene, 2018-04, Vol.37 (14), p.1911-1925

2018

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APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

Oncotarget, 2018-01, Vol.9 (4), p.4537-4548

2018

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The BBN model: a mouse bladder cancer model featuring basalsubtype gene expression and MLL3/MLL4 genetic disruption

Oncoscience, 2018-06, Vol.5 (5-6), p.172-173

2018

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DDB2 Activates Rnf43 and Regulates Wnt/β‐catenin Signaling in Colorectal Cancer Cells

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Chromatin recruitment of OGG1 requires cohesin and mediator and is essential for efficient 8-oxoG removal

Nucleic acids research, 2020-09, Vol.48 (16), p.9082

2020

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Phase 1/2 study of XTX101, a masked, tumor-selective Fc-modified anti-CTLA4, in patients with advanced solid tumors

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.e14685-e14685

2023

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Early Suppression of Immune Regulatory Mechanisms Reduces Tumor Progression in a Murine Model of Urothelial Cancer

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.244-244.9

2020

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Abstract B29: A carcinogen-induced mouse model recapitulates the molecular alterations of human muscle-invasive bladder cancer

Cancer research (Chicago, Ill.), 2018-05, Vol.78 (10_Supplement), p.B29-B29

2018

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MutSignatures: an R package for extraction and analysis of cancer mutational signatures

Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy

Identification of Differential Tumor Subtypes of T1 Bladder Cancer

DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer

APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions

DIscBIO: A User-Friendly Pipeline for Biomarker Discovery in Single-Cell Transcriptomics

The prion protein is critical for DNA repair and cell survival after genotoxic stress

Baricitinib-associated changes in global gene expression during a 24-week phase II clinical systemic lupus erythematosus trial implicates a mechanism of action through multiple immune-related pathways

Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma

1056 XTX301, a tumor activated, half-life extended IL-12 promoted potent anti-tumor immunity and activity across multiple syngeneic tumor models

611 XTX202–01/02–001, Phase 1/2 first-in human study of XTX202, a masked, tumor-activated IL-2βγ, in patients with advanced solid tumors: results from phase 1

Analysis of Mutational Signatures Using the mutSignatures R Library

Molecular footprints of muscle-invasive bladder cancer in smoking and nonsmoking patients

Genomic classification and risk stratification of bladder cancer

A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer

APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

The BBN model: a mouse bladder cancer model featuring basalsubtype gene expression and MLL3/MLL4 genetic disruption

DDB2 Activates Rnf43 and Regulates Wnt/β‐catenin Signaling in Colorectal Cancer Cells

Chromatin recruitment of OGG1 requires cohesin and mediator and is essential for efficient 8-oxoG removal

Phase 1/2 study of XTX101, a masked, tumor-selective Fc-modified anti-CTLA4, in patients with advanced solid tumors

Early Suppression of Immune Regulatory Mechanisms Reduces Tumor Progression in a Murine Model of Urothelial Cancer

Abstract B29: A carcinogen-induced mouse model recapitulates the molecular alterations of human muscle-invasive bladder cancer

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