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An Update on JAK Inhibitors

Current medicinal chemistry, 2019-01, Vol.26 (10), p.1806-1832

2019

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Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors

Current medicinal chemistry, 2017-06, Vol.24 (19), p.2059

2017

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Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors

Molecules (Basel, Switzerland), 2018-09, Vol.23 (9), p.2369

2018

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The impact of electronic health records on healthcare quality: a systematic review and meta-analysis

European journal of public health, 2016-02, Vol.26 (1), p.60-64

2016

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The Pyrazolo[3,4- d ]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma

Biomedicines, 2022-03, Vol.10 (3), p.659

2022

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Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry

ACS medicinal chemistry letters, 2013-02, Vol.4 (2), p.274-277

2013

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Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment

Bioorganic & medicinal chemistry letters, 2018-11, Vol.28 (21), p.3454-3457

2018

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Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma

European journal of medicinal chemistry, 2021-11, Vol.223, p.113653-113653, Article 113653

2021

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Abstract 2201: Preclinical development of novel pyrazolo[3,4- d ]pyrimidines structure-based TKIs for the treatment of glioblastoma

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2201-2201

2019

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Prodrugs of Pyrazolo[3,4‑d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model

Journal of medicinal chemistry, 2017-07, Vol.60 (14), p.6305-6320

2017

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Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma

European journal of medicinal chemistry, 2017-02, Vol.127, p.369-378

2017

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Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line

Bioorganic & medicinal chemistry letters, 2017-07, Vol.27 (14), p.3196-3200

2017

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Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction

European journal of medicinal chemistry, 2018-09, Vol.157, p.743-758

2018

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High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (1), p.280-282

2014

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4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA–PB1 Protein–Protein Interaction: Structure–Activity Relationships Exploration with the Aid of Molecular Modeling

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2688-2703

2016

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Combining X‑ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4‑d]pyrimidines as Potent c‑Src Inhibitors Active in Vivo against Neuroblastoma

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.347-361

2015

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Protein–protein interactions and human cellular cofactors as new targets for HIV therapy

Current opinion in pharmacology, 2014-10, Vol.18, p.1-8

2014

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Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines

European journal of medicinal chemistry, 2019-11, Vol.181, p.111545-111545, Article 111545

2019

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Insight into the Allosteric Inhibition of Abl Kinase

Journal of chemical information and modeling, 2014-05, Vol.54 (5), p.1325-1338

2014

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Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors

Expert opinion on therapeutic patents, 2017-12, Vol.27 (12), p.1305-1318

2017

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Design, Synthesis, and Biological Evaluation of Pyrazolo[3,4‑d]pyrimidines Active in Vivo on the Bcr-Abl T315I Mutant

Journal of medicinal chemistry, 2013-07, Vol.56 (13), p.5382-5394

2013

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Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors

Journal of medicinal chemistry, 2015-06, Vol.58 (11), p.4590-4609

2015

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Identification of Aminoimidazole and Aminothiazole Derivatives as Src Family Kinase Inhibitors

ChemMedChem, 2015-12, Vol.10 (12), p.2027-2041

2015

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The Fight against the Influenza A Virus H1N1: Synthesis, Molecular Modeling, and Biological Evaluation of Benzofurazan Derivatives as Viral RNA Polymerase Inhibitors

ChemMedChem, 2014-01, Vol.9 (1), p.129-150

2014

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An Update on JAK Inhibitors

Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors

Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors

The impact of electronic health records on healthcare quality: a systematic review and meta-analysis

The Pyrazolo[3,4- d ]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma

Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry

Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment

Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma

Abstract 2201: Preclinical development of novel pyrazolo[3,4- d ]pyrimidines structure-based TKIs for the treatment of glioblastoma

Prodrugs of Pyrazolo[3,4‑d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model

Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma

Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line

Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction

High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction

4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA–PB1 Protein–Protein Interaction: Structure–Activity Relationships Exploration with the Aid of Molecular Modeling

Combining X‑ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4‑d]pyrimidines as Potent c‑Src Inhibitors Active in Vivo against Neuroblastoma

Protein–protein interactions and human cellular cofactors as new targets for HIV therapy

Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines

Insight into the Allosteric Inhibition of Abl Kinase

Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors

A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4- d ]Pyrimidine Dual Src/P-Glycoprotein Inhibitor

Design, Synthesis, and Biological Evaluation of Pyrazolo[3,4‑d]pyrimidines Active in Vivo on the Bcr-Abl T315I Mutant

Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors

Identification of Aminoimidazole and Aminothiazole Derivatives as Src Family Kinase Inhibitors

The Fight against the Influenza A Virus H1N1: Synthesis, Molecular Modeling, and Biological Evaluation of Benzofurazan Derivatives as Viral RNA Polymerase Inhibitors

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