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Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update

Trends in microbiology (Regular ed.), 2015-05, Vol.23 (5), p.257-266

2015

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A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages

PloS one, 2018-05, Vol.13 (5), p.e0196678

2018

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Bacterial chemoreceptors: high-performance signaling in networked arrays

Trends in biochemical sciences (Amsterdam. Regular ed.), 2008-01, Vol.33 (1), p.9-19

2008

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Ras signaling mechanisms: New insights from single-molecule biophysics

Biophysical journal, 2024-10, Vol.123 (19), p.3277-3280

2024

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Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway

Biophysical journal, 2016-04, Vol.110 (8), p.1811-1825

2016

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PDK1:PKCα heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane

Biophysical journal, 2023-06, Vol.122 (11), p.2301-2310

2023

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Piston versus Scissors: Chemotaxis Receptors versus Sensor His-Kinase Receptors in Two-Component Signaling Pathways

Structure (London), 2014-09, Vol.22 (9), p.1219-1220

Falke, Joseph J.

2014

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Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating

PloS one, 2020-05, Vol.15 (5), p.e0233012

2020

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Single-molecule studies reveal regulatory interactions between master kinases PDK1, AKT1, and PKC

Biophysical journal, 2021-12, Vol.120 (24), p.5657-5673

2021

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Single Molecule Diffusion of Membrane-Bound Proteins: Window into Lipid Contacts and Bilayer Dynamics

Biophysical journal, 2010-11, Vol.99 (9), p.2879-2887

2010

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Architecture and signal transduction mechanism of the bacterial chemosensory array: Progress, controversies, and challenges

Current opinion in structural biology, 2014-12, Vol.29, p.85-94

2014

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Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling

Biophysical journal, 2017-12, Vol.113 (11), p.2396-2405

2017

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Lateral diffusion of peripheral membrane proteins on supported lipid bilayers is controlled by the additive frictional drags of (1) bound lipids and (2) protein domains penetrating into the bilayer hydrocarbon core

Chemistry and physics of lipids, 2013-07, Vol.172-173, p.67-77

2013

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The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism

Biophysical journal, 2020-12, Vol.119 (11), p.2205-2218

2020

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Single-Molecule Fluorescence Studies of a PH Domain: New Insights into the Membrane Docking Reaction

Biophysical journal, 2009-01, Vol.96 (2), p.566-582

2009

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Evidence that opioids may have toll-like receptor 4 and MD-2 effects

Brain, behavior, and immunity, 2010-01, Vol.24 (1), p.83-95

2010

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The 3.2 Å Resolution Structure of a Receptor:CheA:CheW Signaling Complex Defines Overlapping Binding Sites and Key Residue Interactions within Bacterial Chemosensory Arrays

Biochemistry (Easton), 2013-06, Vol.52 (22), p.3852-3865

2013

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Structure of the Conserved HAMP Domain in an Intact, Membrane-Bound Chemoreceptor: A Disulfide Mapping Study

Biochemistry (Easton), 2007-12, Vol.46 (48), p.13684-13695

2007

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Interactions of Protein Kinase C‑α C1A and C1B Domains with Membranes: A Combined Computational and Experimental Study

Journal of the American Chemical Society, 2014-08, Vol.136 (33), p.11757-11766

2014

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HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase

Analytical biochemistry, 2021-10, Vol.631, p.114338-114338, Article 114338

2021

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Molecular Mechanism of Membrane Binding of the GRP1 PH Domain

Journal of molecular biology, 2013-09, Vol.425 (17), p.3073-3090

2013

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Engineered Socket Study of Signaling through a Four-Helix Bundle: Evidence for a Yin−Yang Mechanism in the Kinase Control Module of the Aspartate Receptor

Biochemistry (Easton), 2009-10, Vol.48 (39), p.9266-9277

2009

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Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cells

Chemistry and physics of lipids, 2014-09, Vol.182, p.73-79

2014

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Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements

Analytical biochemistry, 2023-02, Vol.663, p.115019-115019, Article 115019

2023

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Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain

Biochemistry (Easton), 2008-11, Vol.47 (47), p.12260-12269

2008

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Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update

A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages

Bacterial chemoreceptors: high-performance signaling in networked arrays

Ras signaling mechanisms: New insights from single-molecule biophysics

Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway

PDK1:PKCα heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane

Piston versus Scissors: Chemotaxis Receptors versus Sensor His-Kinase Receptors in Two-Component Signaling Pathways

Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating

Single-molecule studies reveal regulatory interactions between master kinases PDK1, AKT1, and PKC

Single Molecule Diffusion of Membrane-Bound Proteins: Window into Lipid Contacts and Bilayer Dynamics

Architecture and signal transduction mechanism of the bacterial chemosensory array: Progress, controversies, and challenges

Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling

Lateral diffusion of peripheral membrane proteins on supported lipid bilayers is controlled by the additive frictional drags of (1) bound lipids and (2) protein domains penetrating into the bilayer hydrocarbon core

The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism

Single-Molecule Fluorescence Studies of a PH Domain: New Insights into the Membrane Docking Reaction

Evidence that opioids may have toll-like receptor 4 and MD-2 effects

The 3.2 Å Resolution Structure of a Receptor:CheA:CheW Signaling Complex Defines Overlapping Binding Sites and Key Residue Interactions within Bacterial Chemosensory Arrays

Structure of the Conserved HAMP Domain in an Intact, Membrane-Bound Chemoreceptor: A Disulfide Mapping Study

Interactions of Protein Kinase C‑α C1A and C1B Domains with Membranes: A Combined Computational and Experimental Study

HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase

Molecular Mechanism of Membrane Binding of the GRP1 PH Domain

Engineered Socket Study of Signaling through a Four-Helix Bundle: Evidence for a Yin−Yang Mechanism in the Kinase Control Module of the Aspartate Receptor

Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cells

Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements

Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain

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