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Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia

Cell chemical biology, 2018-07, Vol.25 (7), p.891-905.e8

2018

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Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation

Molecules (Basel, Switzerland), 2020-06, Vol.25 (12), p.2911

2020

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Protein dynamics of the HIF-2α PAS-B domain upon heterodimerization and ligand binding

PloS one, 2014-04, Vol.9 (4), p.e94986-e94986

2014

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Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (5), p.2094-2098

2012

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Structure-Based Virtual Screening Allows the Identification of Efficient Modulators of E-Cadherin-Mediated Cell-Cell Adhesion

International journal of molecular sciences, 2019-07, Vol.20 (14), p.3404

2019

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Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication

Viruses, 2021-05, Vol.13 (5), p.941

2021

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A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation

Bioorganic & medicinal chemistry letters, 2012-09, Vol.22 (17), p.5579-5583

2012

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Probing allosteric communication with combined molecular dynamics simulations and network analysis

Current opinion in structural biology, 2024-06, Vol.86, p.102820-102820, Article 102820

2024

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Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1207-1211

2008

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Radial access for percutaneous coronary procedure: relationship between operator expertise and complications

Clinical and Experimental Emergency Medicine, 2018, 5(2), , pp.95-99

2018

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Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives

Journal of medicinal chemistry, 2022-04, Vol.65 (7), p.5212-5243

2022

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Structure-based design of small-molecule protein-protein interaction modulators: the story so far

Future medicinal chemistry, 2014-03, Vol.6 (3), p.343-357

2014

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Protein Tunnels: The Case of Urease Accessory Proteins

Journal of chemical theory and computation, 2017-05, Vol.13 (5), p.2322-2331

2017

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2‑Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile

Journal of medicinal chemistry, 2015-08, Vol.58 (16), p.6422-6434

2015

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Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib

Journal of medicinal chemistry, 2020-03, Vol.63 (5), p.2588-2619

2020

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Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach

Retrovirology, 2012-05, Vol.9 (S1), p.P5-P5, Article P5

2012

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Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach

Journal of medicinal chemistry, 2021-12, Vol.64 (23), p.17277-17286

2021

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Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase

Retrovirology, 2010-05, Vol.7 (S1), p.O16-O16, Article O16

2010

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Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification

Analytical chemistry (Washington), 2016-10, Vol.88 (19), p.9510-9517

2016

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Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells

European journal of medicinal chemistry, 2019-03, Vol.165, p.80-92

2019

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Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5

Journal of medicinal chemistry, 2023-07, Vol.66 (14), p.9797-9822

2023

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Development of a multisite model for Ni(II) ion in solution from thermodynamic and kinetic data

Journal of computational chemistry, 2017-08, Vol.38 (21), p.1834-1843

2017

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Correction to “Novel Antiproliferative Chimeric Compounds with Marked Histone Deacetylase Inhibitory Activity”

ACS medicinal chemistry letters, 2024-08, Vol.15 (8), p.1402-1402

2024

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Protein dynamics of the HIF-2[alpha] PAS-B domain upon heterodimerization and ligand binding

PloS one, 2014-04, Vol.9 (4)

2014

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From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold

Bioorganic & medicinal chemistry letters, 2015-07, Vol.25 (14), p.2804-2808

2015

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Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia

Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation

Protein dynamics of the HIF-2α PAS-B domain upon heterodimerization and ligand binding

Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors

Structure-Based Virtual Screening Allows the Identification of Efficient Modulators of E-Cadherin-Mediated Cell-Cell Adhesion

Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication

A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation

Probing allosteric communication with combined molecular dynamics simulations and network analysis

Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents

Radial access for percutaneous coronary procedure: relationship between operator expertise and complications

Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives

Structure-based design of small-molecule protein-protein interaction modulators: the story so far

Protein Tunnels: The Case of Urease Accessory Proteins

2‑Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile

Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib

Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach

Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach

Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase

Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification

Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells

Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5

Development of a multisite model for Ni(II) ion in solution from thermodynamic and kinetic data

Correction to “Novel Antiproliferative Chimeric Compounds with Marked Histone Deacetylase Inhibitory Activity”

Protein dynamics of the HIF-2[alpha] PAS-B domain upon heterodimerization and ligand binding

From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold

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