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Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

Nature communications, 2013-01, Vol.4 (1), p.2384-2384, Article 2384

2013

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Organs-on-chips (microphysiological systems): tools to expedite efficacy and toxicity testing in human tissue

Experimental biology and medicine (Maywood, N.J.), 2014-09, Vol.239 (9), p.1073-1077

2014

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The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipeline

Stem cell research & therapy, 2013-12, Vol.4 Suppl 1 (Suppl 1), p.I1-I1, Article I1

2013

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Utilizing microphysiological systems and induced pluripotent stem cells for disease modeling: a case study for blood brain barrier research in a pharmaceutical setting

Advanced drug delivery reviews, 2019-02, Vol.140, p.129-135

2019

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Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective

Experimental biology and medicine (Maywood, N.J.), 2017-10, Vol.242 (16), p.1579-1585

2017

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On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships

Scientific reports, 2019-07, Vol.9 (1), p.9619-14, Article 9619

2019

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In vitro and In vivo Radiation Sensitization of Human Tumor Cells by a Novel Checkpoint Kinase Inhibitor, AZD7762

Clinical cancer research, 2010-04, Vol.16 (7), p.2076-2084

2010

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Facilitating the commercialization and use of organ platforms generated by the microphysiological systems (Tissue Chip) program through public–private partnerships

Computational and structural biotechnology journal, 2016-01, Vol.14 (C), p.207-210

2016

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The Need for Biological Countermeasures to Mitigate the Risk of Space Radiation-Induced Carcinogenesis, Cardiovascular Disease, and Central Nervous System Deficiencies

Life sciences in space research, 2022-11, Vol.35 (C), p.4-8

2022

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Cancer Incidence in C3H Mice Protected from Lethal Total-Body Radiation after Amifostine

Radiation research, 2018-05, Vol.189 (5), p.490-496

2018

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The effects of resveratrol and selected metabolites on the radiation and antioxidant response

Cancer biology & therapy, 2011-11, Vol.12 (10), p.915-923

2011

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Murine Prkdc Polymorphisms Impact DNA-PKcs Function

Radiation research, 2011-04, Vol.175 (4), p.493-500

2011

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Spaceflight Associated Neuro-Ocular Syndrome: New Technologies to Advance Research in a Fast Moving Field

New space (New Rochelle, NY), 2023-03, Vol.11 (1), p.2-5

2023

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Introduction to a manuscript series on the characterization and use of microphysiological systems (MPS) in pharmaceutical safety and ADME applications

Lab on a chip, 2020-03, Vol.20 (6), p.1049-1057

2020

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Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery

Annual review of pharmacology and toxicology, 2018-01, Vol.58 (1), p.65-82

2018

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Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex in vitro models and assays

Lab on a chip, 2020-01, Vol.20 (2), p.199-214

2020

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A SERS-Active Electrospun Polymer Mesh for Spatially Localized pH Measurements of the Cellular Microenvironment

Analytical chemistry (Washington), 2021-10, Vol.93 (41), p.13844-13851

2021

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Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex models and assays

Lab on a chip, 2020-01, Vol.2 (2), p.199-214

2020

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A Tiered Female Ovarian Toxicity Screening Identifies Toxic Effects of Checkpoint Kinase 1 Inhibitors on Murine Growing Follicles

Toxicological sciences, 2020-10, Vol.177 (2), p.405-419

2020

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The Need for Biological Countermeasures to Mitigate the Risk of Space Radiation-Induced Carcinogenesis, Cardiovascular Disease, and Central Nervous System Deficiencies

Life sciences in space research, 2022-11, Vol.35 (C)

2022

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Deep-space applications for point-of-care technologies

Current opinion in biomedical engineering, 2019-09, Vol.11, p.45-50

2019

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Prkdc polymorphisms and radiation effects

Askin, Kristin Fabre

2008

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The ecological origins of snakes as revealed by skull evolution

Nature communications, 2018-01, Vol.9 (1), p.376-11, Article 376

2018

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Role of serum response factor expression in prostate cancer biochemical recurrence

The Prostate, 2018-07, Vol.78 (10), p.724-730

2018

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Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

Organs-on-chips (microphysiological systems): tools to expedite efficacy and toxicity testing in human tissue

The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipeline

Utilizing microphysiological systems and induced pluripotent stem cells for disease modeling: a case study for blood brain barrier research in a pharmaceutical setting

Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective

On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships

In vitro and In vivo Radiation Sensitization of Human Tumor Cells by a Novel Checkpoint Kinase Inhibitor, AZD7762

Facilitating the commercialization and use of organ platforms generated by the microphysiological systems (Tissue Chip) program through public–private partnerships

The Need for Biological Countermeasures to Mitigate the Risk of Space Radiation-Induced Carcinogenesis, Cardiovascular Disease, and Central Nervous System Deficiencies

A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models

Cancer Incidence in C3H Mice Protected from Lethal Total-Body Radiation after Amifostine

The effects of resveratrol and selected metabolites on the radiation and antioxidant response

Murine Prkdc Polymorphisms Impact DNA-PKcs Function

Spaceflight Associated Neuro-Ocular Syndrome: New Technologies to Advance Research in a Fast Moving Field

Introduction to a manuscript series on the characterization and use of microphysiological systems (MPS) in pharmaceutical safety and ADME applications

Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery

Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex in vitro models and assays

A SERS-Active Electrospun Polymer Mesh for Spatially Localized pH Measurements of the Cellular Microenvironment

Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex models and assays

A Tiered Female Ovarian Toxicity Screening Identifies Toxic Effects of Checkpoint Kinase 1 Inhibitors on Murine Growing Follicles

The Need for Biological Countermeasures to Mitigate the Risk of Space Radiation-Induced Carcinogenesis, Cardiovascular Disease, and Central Nervous System Deficiencies

Deep-space applications for point-of-care technologies

Prkdc polymorphisms and radiation effects

The ecological origins of snakes as revealed by skull evolution

Role of serum response factor expression in prostate cancer biochemical recurrence

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